(76 nodes) Regulation of cell morphogenesis network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	F6ZEC7_CIOIN	WD_REPEATS_REGION domain-containing protein. (299 aa)
	F6SGK0_CIOIN	Tyrosine-protein kinase. (954 aa)
	LOC100185717	Uncharacterized protein. (623 aa)
	F6VQE7_CIOIN	Uncharacterized protein. (223 aa)
	F6RL50_CIOIN	Uncharacterized protein. (303 aa)
	cdc42	Uncharacterized protein. (95 aa)
	Zf(c2h2)-69	Uncharacterized protein. (940 aa)
	LOC100184368	Integrin-linked protein kinase. (447 aa)
	LOC100178597	Myeloid-associated differentiation marker-like protein 2 isoform X1. (285 aa)
	F6W6K0_CIOIN	Uncharacterized protein. (534 aa)
	LOC448957	Rac4 protein. (193 aa)
	Rac3a	Uncharacterized protein. (194 aa)
	LOC448958	Rac5 protein. (193 aa)
	LOC445702	Rac1 protein isoform X1. (192 aa)
	F6YDG1_CIOIN	CULLIN_2 domain-containing protein; Belongs to the cullin family. (586 aa)
	F6SC38_CIOIN	LisH domain-containing protein. (739 aa)
	F6RD62_CIOIN	Uncharacterized protein. (377 aa)
	rhoc	RhoA protein. (193 aa)
	F7AXL0_CIOIN	Uncharacterized protein. (1039 aa)
	F6WUP4_CIOIN	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1014 aa)
	LOC100181221	Integumentary mucin C.1-like. (367 aa)
	F6TXZ8_CIOIN	Uncharacterized protein. (359 aa)
	LOC100176196	Protein RCC2 homolog. (475 aa)
	F6S5L9_CIOIN	SH3 domain-containing protein. (774 aa)
	rcl2	Rac and Cdc42-like 2 protein isoform X1. (192 aa)
	F7A9M5_CIOIN	Uncharacterized protein. (801 aa)
	LOC100176674	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (278 aa)
	capzb	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (273 aa)
	F6ZFJ9_CIOIN	Alpha-type protein kinase domain-containing protein. (678 aa)
	F7B1D2_CIOIN	Uncharacterized protein. (794 aa)
	F6ZEC1_CIOIN	WD_REPEATS_REGION domain-containing protein. (198 aa)
	Syt1	Uncharacterized protein. (328 aa)
	F6UMA7_CIOIN	PID domain-containing protein. (458 aa)
	F6R4T5_CIOIN	Uncharacterized protein. (815 aa)
	F7A1R5_CIOIN	Uncharacterized protein. (750 aa)
	F6UDR5_CIOIN	Uncharacterized protein. (723 aa)
	LOC445704	TC10 protein. (193 aa)
	F6YM26_CIOIN	Uncharacterized protein. (155 aa)
	rngi	Caprin-1_dimer domain-containing protein. (703 aa)
	F6S0L5_CIOIN	Uncharacterized protein. (985 aa)
	F7ABT2_CIOIN	Sema domain-containing protein. (1549 aa)
	F6TAV4_CIOIN	RING-type domain-containing protein. (382 aa)
	F6VYF2_CIOIN	Uncharacterized protein. (797 aa)
	F6V8F4_CIOIN	Uncharacterized protein. (215 aa)
	rhob	Rif protein. (249 aa)
	Rac2	Uncharacterized protein. (192 aa)
	F6TTH0_CIOIN	Uncharacterized protein. (426 aa)
	Zf(rbz)-3	Uncharacterized protein. (687 aa)
	F6V476_CIOIN	Uncharacterized protein. (282 aa)
	F7B221_CIOIN	LIM domain-containing protein. (326 aa)
	Erm	FERM domain-containing protein. (582 aa)
	rcl1	Rac and Cdc42-like 1 protein. (194 aa)
	LOC100177517	Craniofacial development protein 1; May play a role during embryogenesis. (241 aa)
	F7AIB9_CIOIN	Uncharacterized protein. (271 aa)
	H2XKM4_CIOIN	IPT/TIG domain-containing protein. (187 aa)
	H2XKU1_CIOIN	CRIB domain-containing protein. (218 aa)
	H2XL71_CIOIN	Uncharacterized protein. (116 aa)
	LOC100186675	AP-1 complex-associated regulatory protein isoform X1. (287 aa)
	H2XMB5_CIOIN	Uncharacterized protein. (116 aa)
	H2XPL3_CIOIN	Uncharacterized protein. (434 aa)
	H2XR40_CIOIN	RING-type domain-containing protein. (355 aa)
	H2XRP4_CIOIN	Uncharacterized protein. (126 aa)
	H2XS74_CIOIN	Uncharacterized protein. (301 aa)
	H2XT32_CIOIN	Uncharacterized protein. (127 aa)
	H2XUL2_CIOIN	Uncharacterized protein. (299 aa)
	ENSCINP00000033553	annotation not available (74 aa)
	H2XWW8_CIOIN	Olfactomedin-like domain-containing protein. (121 aa)
	H2XYC4_CIOIN	CRIB domain-containing protein. (85 aa)
	H2XZ90_CIOIN	Uncharacterized protein. (336 aa)
	H2Y0C2_CIOIN	Uncharacterized protein. (138 aa)
	H2Y0V6_CIOIN	Uncharacterized protein. (204 aa)
	H2Y1D3_CIOIN	Uncharacterized protein. (132 aa)
	H2Y1K9_CIOIN	Uncharacterized protein. (674 aa)
	H2Y2K0_CIOIN	Uncharacterized protein. (399 aa)
	H2Y2U9_CIOIN	Uncharacterized protein. (884 aa)
	H2Y3R6_CIOIN	Uncharacterized protein. (156 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCINP00000033553	F6RD62_CIOIN	ENSCINP00000033553	ENSCINP00000006303	annotation not available	Uncharacterized protein.	0.405
ENSCINP00000033553	F6UDR5_CIOIN	ENSCINP00000033553	ENSCINP00000017504	annotation not available	Uncharacterized protein.	0.540
ENSCINP00000033553	F7ABT2_CIOIN	ENSCINP00000033553	ENSCINP00000019818	annotation not available	Sema domain-containing protein.	0.540
ENSCINP00000033553	rhob	ENSCINP00000033553	ENSCINP00000023349	annotation not available	Rif protein.	0.436
ENSCINP00000033553	rhoc	ENSCINP00000033553	ENSCINP00000006386	annotation not available	RhoA protein.	0.525
Erm	cdc42	ENSCINP00000025580	ENSCINP00000001500	FERM domain-containing protein.	Uncharacterized protein.	0.547
Erm	rhoc	ENSCINP00000025580	ENSCINP00000006386	FERM domain-containing protein.	RhoA protein.	0.561
F6R4T5_CIOIN	F6W6K0_CIOIN	ENSCINP00000016826	ENSCINP00000004081	Uncharacterized protein.	Uncharacterized protein.	0.443
F6RD62_CIOIN	ENSCINP00000033553	ENSCINP00000006303	ENSCINP00000033553	Uncharacterized protein.	annotation not available	0.405
F6RD62_CIOIN	F6UDR5_CIOIN	ENSCINP00000006303	ENSCINP00000017504	Uncharacterized protein.	Uncharacterized protein.	0.405
F6RD62_CIOIN	F6VYF2_CIOIN	ENSCINP00000006303	ENSCINP00000022526	Uncharacterized protein.	Uncharacterized protein.	0.413
F6RD62_CIOIN	F7ABT2_CIOIN	ENSCINP00000006303	ENSCINP00000019818	Uncharacterized protein.	Sema domain-containing protein.	0.405
F6RD62_CIOIN	H2XKM4_CIOIN	ENSCINP00000006303	ENSCINP00000030206	Uncharacterized protein.	IPT/TIG domain-containing protein.	0.405
F6RD62_CIOIN	LOC100181221	ENSCINP00000006303	ENSCINP00000009173	Uncharacterized protein.	Integumentary mucin C.1-like.	0.413
F6RD62_CIOIN	cdc42	ENSCINP00000006303	ENSCINP00000001500	Uncharacterized protein.	Uncharacterized protein.	0.458
F6RD62_CIOIN	rhob	ENSCINP00000006303	ENSCINP00000023349	Uncharacterized protein.	Rif protein.	0.452
F6RD62_CIOIN	rhoc	ENSCINP00000006303	ENSCINP00000006386	Uncharacterized protein.	RhoA protein.	0.812
F6S0L5_CIOIN	F6S5L9_CIOIN	ENSCINP00000018851	ENSCINP00000011338	Uncharacterized protein.	SH3 domain-containing protein.	0.433
F6S0L5_CIOIN	LOC445702	ENSCINP00000018851	ENSCINP00000004782	Uncharacterized protein.	Rac1 protein isoform X1.	0.518
F6S0L5_CIOIN	LOC448957	ENSCINP00000018851	ENSCINP00000004748	Uncharacterized protein.	Rac4 protein.	0.518