(91 nodes) Extracellular matrix organization network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100179371	EGF-containing fibulin-like extracellular matrix protein 1. (531 aa)
	F6VQ85_CIOIN	Uncharacterized protein. (384 aa)
	F6PX32_CIOIN	P-type domain-containing protein. (600 aa)
	F6ZTT9_CIOIN	Uncharacterized protein. (1149 aa)
	LOC100177697	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (236 aa)
	F6Z448_CIOIN	Fibrillar collagen NC1 domain-containing protein. (1454 aa)
	LOC100185184	SPARC-related modular calcium-binding protein 2 isoform X1. (682 aa)
	F6S2P7_CIOIN	Uncharacterized protein. (194 aa)
	F7APX0_CIOIN	Uncharacterized protein. (1090 aa)
	F6TLB6_CIOIN	Uncharacterized protein. (891 aa)
	F6U6Y7_CIOIN	Uncharacterized protein. (421 aa)
	F7AC12_CIOIN	Uncharacterized protein. (377 aa)
	F7ABP5_CIOIN	Olfactomedin-like domain-containing protein. (214 aa)
	LOC101242989	Uncharacterized protein. (592 aa)
	F6YH85_CIOIN	Uncharacterized protein. (518 aa)
	LOC100176604	Sulfatase domain-containing protein. (833 aa)
	sfrp2	Secreted frizzled-related protein isoform X1. (293 aa)
	F6TV99_CIOIN	Uncharacterized protein. (242 aa)
	F7AU99_CIOIN	Uncharacterized protein. (758 aa)
	F6PUJ2_CIOIN	Uncharacterized protein. (338 aa)
	F7B1K2_CIOIN	Uncharacterized protein. (250 aa)
	F6YBI0_CIOIN	Uncharacterized protein. (231 aa)
	LOC100179911	Uncharacterized protein. (1602 aa)
	F6PSM8_CIOIN	Uncharacterized protein. (690 aa)
	F6RRU7_CIOIN	ZnMc domain-containing protein. (540 aa)
	LOC100181205	Protein O-mannosyl-transferase 1-like isoform X1. (664 aa)
	F6RLA4_CIOIN	ZnMc domain-containing protein. (503 aa)
	F6QQZ3_CIOIN	Thioredoxin domain-containing protein. (202 aa)
	F6RJA6_CIOIN	Uncharacterized protein. (322 aa)
	F6RI21_CIOIN	Uncharacterized protein. (355 aa)
	F6SYX7_CIOIN	Uncharacterized protein. (624 aa)
	F6WWH2_CIOIN	PH domain-containing protein. (715 aa)
	LOC100180059	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (626 aa)
	F6SUU2_CIOIN	Peptidase M12B domain-containing protein. (1836 aa)
	F6SUT6_CIOIN	Uncharacterized protein. (1145 aa)
	F6RZH2_CIOIN	Uncharacterized protein. (617 aa)
	LOC100185687	Collagen alpha-1(XII) chain. (172 aa)
	F6SK07_CIOIN	VWFA domain-containing protein. (430 aa)
	F7A2D4_CIOIN	BPTI/Kunitz inhibitor domain-containing protein. (271 aa)
	F6X4H6_CIOIN	Uncharacterized protein; Belongs to the peptidase S1 family. (978 aa)
	F6WTL7_CIOIN	Collagen IV NC1 domain-containing protein. (1771 aa)
	LOC100185145	Collagen IV NC1 domain-containing protein. (1729 aa)
	F6STG8_CIOIN	Uncharacterized protein. (407 aa)
	F6ZRP3_CIOIN	Uncharacterized protein. (655 aa)
	LOC100185581	Uncharacterized protein LOC100185581 isoform X1. (462 aa)
	F6UEW3_CIOIN	Fibrillar collagen NC1 domain-containing protein. (1218 aa)
	F6TR93_CIOIN	ZnMc domain-containing protein. (503 aa)
	Tgfbeta2	TGF_BETA_2 domain-containing protein. (435 aa)
	F6Q5T5_CIOIN	Peptidase M12B domain-containing protein. (1486 aa)
	F6S2X9_CIOIN	Uncharacterized protein. (417 aa)
	F6Z4Y8_CIOIN	Uncharacterized protein. (187 aa)
	F6Z4W7_CIOIN	Uncharacterized protein. (1746 aa)
	F6Z402_CIOIN	Peptidase S72 domain-containing protein. (410 aa)
	LOC100179435	Uncharacterized protein. (393 aa)
	foxf	Fork-head domain-containing protein. (575 aa)
	F6Y8V9_CIOIN	Uncharacterized protein. (1172 aa)
	Collagen_XVIII	Endostatin domain-containing protein. (950 aa)
	F6PIT9_CIOIN	Uncharacterized protein. (210 aa)
	F6UHX2_CIOIN	ZnMc domain-containing protein; Belongs to the peptidase M10A family. (508 aa)
	F6U5Q2_CIOIN	Uncharacterized protein. (203 aa)
	F7A9D2_CIOIN	Uncharacterized protein. (323 aa)
	F6ZGK8_CIOIN	Uncharacterized protein. (639 aa)
	F6RQK4_CIOIN	Uncharacterized protein. (248 aa)
	F6R9B7_CIOIN	Fibrillar collagen NC1 domain-containing protein. (262 aa)
	F6Q1Z4_CIOIN	VWFA domain-containing protein. (959 aa)
	F6QJY0_CIOIN	Uncharacterized protein. (458 aa)
	F6Y6R0_CIOIN	Uncharacterized protein. (393 aa)
	F6W3W9_CIOIN	Uncharacterized protein. (758 aa)
	F6T2G1_CIOIN	Uncharacterized protein. (298 aa)
	zf(c2h2)-84	A disintegrin and metalloproteinase with thrombospondin motifs 4. (1030 aa)
	H2XKP9_CIOIN	Uncharacterized protein. (329 aa)
	H2XLP7_CIOIN	VWFA domain-containing protein. (209 aa)
	ENSCINP00000030701	Matrix metalloproteinase-2 (gelatinase A). (111 aa)
	H2XM82_CIOIN	Uncharacterized protein. (190 aa)
	LOC100178517	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (142 aa)
	H2XNW9_CIOIN	Uncharacterized protein. (163 aa)
	H2XPS3_CIOIN	Uncharacterized protein. (971 aa)
	H2XRQ0_CIOIN	C1q domain-containing protein. (479 aa)
	H2XS44_CIOIN	BPTI/Kunitz inhibitor domain-containing protein. (523 aa)
	H2XSQ5_CIOIN	Uncharacterized protein. (939 aa)
	H2XT11_CIOIN	Uncharacterized protein. (68 aa)
	H2XUJ1_CIOIN	Uncharacterized protein. (359 aa)
	H2XVY8_CIOIN	Uncharacterized protein. (331 aa)
	LOC100179334	Peptidase M12B domain-containing protein. (1049 aa)
	LOC100185024	Spermatogenesis-defective protein 39 homolog. (499 aa)
	H2XWS8_CIOIN	Uncharacterized protein. (426 aa)
	H2Y0L2_CIOIN	FAS1 domain-containing protein. (122 aa)
	H2Y192_CIOIN	Uncharacterized protein. (201 aa)
	H2Y255_CIOIN	CTCK domain-containing protein. (191 aa)
	H2Y2K0_CIOIN	Uncharacterized protein. (399 aa)
	H2Y3E3_CIOIN	Uncharacterized protein. (2642 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Collagen_XVIII	F6UEW3_CIOIN	ENSCINP00000019538	ENSCINP00000017221	Endostatin domain-containing protein.	Fibrillar collagen NC1 domain-containing protein.	0.429
ENSCINP00000030701	F6RLA4_CIOIN	ENSCINP00000030701	ENSCINP00000013141	Matrix metalloproteinase-2 (gelatinase A).	ZnMc domain-containing protein.	0.495
ENSCINP00000030701	F6RRU7_CIOIN	ENSCINP00000030701	ENSCINP00000013119	Matrix metalloproteinase-2 (gelatinase A).	ZnMc domain-containing protein.	0.496
ENSCINP00000030701	F6TR93_CIOIN	ENSCINP00000030701	ENSCINP00000017258	Matrix metalloproteinase-2 (gelatinase A).	ZnMc domain-containing protein.	0.503
F6PIT9_CIOIN	F6ZRP3_CIOIN	ENSCINP00000020211	ENSCINP00000016246	Uncharacterized protein.	Uncharacterized protein.	0.404
F6PIT9_CIOIN	F7A9D2_CIOIN	ENSCINP00000020211	ENSCINP00000023644	Uncharacterized protein.	Uncharacterized protein.	0.404
F6PIT9_CIOIN	H2XWS8_CIOIN	ENSCINP00000020211	ENSCINP00000034112	Uncharacterized protein.	Uncharacterized protein.	0.519
F6PSM8_CIOIN	H2XWS8_CIOIN	ENSCINP00000013067	ENSCINP00000034112	Uncharacterized protein.	Uncharacterized protein.	0.449
F6PSM8_CIOIN	LOC101242989	ENSCINP00000013067	ENSCINP00000007858	Uncharacterized protein.	Uncharacterized protein.	0.518
F6PUJ2_CIOIN	F7A9D2_CIOIN	ENSCINP00000011888	ENSCINP00000023644	Uncharacterized protein.	Uncharacterized protein.	0.872
F6QJY0_CIOIN	H2XPS3_CIOIN	ENSCINP00000025593	ENSCINP00000031657	Uncharacterized protein.	Uncharacterized protein.	0.823
F6R9B7_CIOIN	H2XRQ0_CIOIN	ENSCINP00000025199	ENSCINP00000032334	Fibrillar collagen NC1 domain-containing protein.	C1q domain-containing protein.	0.431
F6RLA4_CIOIN	ENSCINP00000030701	ENSCINP00000013141	ENSCINP00000030701	ZnMc domain-containing protein.	Matrix metalloproteinase-2 (gelatinase A).	0.495
F6RRU7_CIOIN	ENSCINP00000030701	ENSCINP00000013119	ENSCINP00000030701	ZnMc domain-containing protein.	Matrix metalloproteinase-2 (gelatinase A).	0.496
F6RZH2_CIOIN	LOC100179911	ENSCINP00000015201	ENSCINP00000013062	Uncharacterized protein.	Uncharacterized protein.	0.585
F6S2P7_CIOIN	H2XM82_CIOIN	ENSCINP00000006574	ENSCINP00000030764	Uncharacterized protein.	Uncharacterized protein.	0.489
F6T2G1_CIOIN	F6TLB6_CIOIN	ENSCINP00000029547	ENSCINP00000007196	Uncharacterized protein.	Uncharacterized protein.	0.950
F6T2G1_CIOIN	F6W3W9_CIOIN	ENSCINP00000029547	ENSCINP00000028344	Uncharacterized protein.	Uncharacterized protein.	0.946
F6TLB6_CIOIN	F6T2G1_CIOIN	ENSCINP00000007196	ENSCINP00000029547	Uncharacterized protein.	Uncharacterized protein.	0.950
F6TLB6_CIOIN	F6W3W9_CIOIN	ENSCINP00000007196	ENSCINP00000028344	Uncharacterized protein.	Uncharacterized protein.	0.949