(35 nodes) Positive regulation of cell growth network (Ciona intestinalis)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	F6ZGR3_CIOIN	Uncharacterized protein. (670 aa)
	H2XJG5_CIOIN	Uncharacterized protein; Belongs to the protein kinase superfamily. (458 aa)
	LOC100182394	Exosome complex component RRP4. (302 aa)
	F7AFQ9_CIOIN	Uncharacterized protein. (482 aa)
	LOC100187445	Probable ATP-dependent RNA helicase DDX49 isoform X1; Belongs to the DEAD box helicase family. (457 aa)
	F6TTH0_CIOIN	Uncharacterized protein. (426 aa)
	wnt3	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (304 aa)
	F6TAV4_CIOIN	RING-type domain-containing protein. (382 aa)
	LOC100180921	Putative 2'-deoxynucleoside 5'-phosphate N-hydrolase 1; Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base. (151 aa)
	F6TKH9_CIOIN	RNase_PH domain-containing protein. (247 aa)
	F6Y9D9_CIOIN	Uncharacterized protein. (768 aa)
	Tgfbeta2	TGF_BETA_2 domain-containing protein. (435 aa)
	F7A1R5_CIOIN	Uncharacterized protein. (750 aa)
	F6Z672_CIOIN	Uncharacterized protein. (648 aa)
	F7APA8_CIOIN	Uncharacterized protein; Belongs to the glycosyltransferase 47 family. (915 aa)
	F6W9Z4_CIOIN	Uncharacterized protein. (90 aa)
	Syt1	Uncharacterized protein. (328 aa)
	LOC100183552	ANK_REP_REGION domain-containing protein. (230 aa)
	F6ZQY6_CIOIN	Poly [ADP-ribose] polymerase. (537 aa)
	sfrp2	Secreted frizzled-related protein isoform X1. (293 aa)
	F7B6D7_CIOIN	COMM domain-containing protein. (224 aa)
	F6SCE7_CIOIN	Uncharacterized protein. (361 aa)
	F6YDG1_CIOIN	CULLIN_2 domain-containing protein; Belongs to the cullin family. (586 aa)
	F6VK85_CIOIN	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (754 aa)
	LOC100176030	WD_REPEATS_REGION domain-containing protein. (1206 aa)
	H2Y1D3_CIOIN	Uncharacterized protein. (132 aa)
	H2Y066_CIOIN	Uncharacterized protein. (361 aa)
	H2XYD4_CIOIN	Uncharacterized protein. (216 aa)
	H2XWT8_CIOIN	Uncharacterized protein. (206 aa)
	srf	Transcription factor protein. (335 aa)
	H2XR85_CIOIN	USP domain-containing protein; Belongs to the peptidase C19 family. (1053 aa)
	H2XR40_CIOIN	RING-type domain-containing protein. (355 aa)
	H2XPL3_CIOIN	Uncharacterized protein. (434 aa)
	H2XM17_CIOIN	FAT domain-containing protein. (187 aa)
	H2XJM9_CIOIN	Uncharacterized protein. (96 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6TKH9_CIOIN	F6Z672_CIOIN	ENSCINP00000019449	ENSCINP00000016544	RNase_PH domain-containing protein.	Uncharacterized protein.	0.540
F6TKH9_CIOIN	H2XJM9_CIOIN	ENSCINP00000019449	ENSCINP00000029861	RNase_PH domain-containing protein.	Uncharacterized protein.	0.998
F6TKH9_CIOIN	LOC100182394	ENSCINP00000019449	ENSCINP00000026787	RNase_PH domain-containing protein.	Exosome complex component RRP4.	0.999
F6TKH9_CIOIN	LOC100187445	ENSCINP00000019449	ENSCINP00000024709	RNase_PH domain-containing protein.	Probable ATP-dependent RNA helicase DDX49 isoform X1; Belongs to the DEAD box helicase family.	0.695
F6VK85_CIOIN	H2XM17_CIOIN	ENSCINP00000002868	ENSCINP00000030699	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	FAT domain-containing protein.	0.943
F6VK85_CIOIN	H2XWT8_CIOIN	ENSCINP00000002868	ENSCINP00000034122	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.925
F6VK85_CIOIN	H2Y066_CIOIN	ENSCINP00000002868	ENSCINP00000035300	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.929
F6VK85_CIOIN	LOC100176030	ENSCINP00000002868	ENSCINP00000001261	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	WD_REPEATS_REGION domain-containing protein.	0.915
F6Z672_CIOIN	F6TKH9_CIOIN	ENSCINP00000016544	ENSCINP00000019449	Uncharacterized protein.	RNase_PH domain-containing protein.	0.540
F6Z672_CIOIN	LOC100182394	ENSCINP00000016544	ENSCINP00000026787	Uncharacterized protein.	Exosome complex component RRP4.	0.540
F6Z672_CIOIN	LOC100187445	ENSCINP00000016544	ENSCINP00000024709	Uncharacterized protein.	Probable ATP-dependent RNA helicase DDX49 isoform X1; Belongs to the DEAD box helicase family.	0.442
F7B6D7_CIOIN	H2XR40_CIOIN	ENSCINP00000008384	ENSCINP00000032124	COMM domain-containing protein.	RING-type domain-containing protein.	0.479
H2XJM9_CIOIN	F6TKH9_CIOIN	ENSCINP00000029861	ENSCINP00000019449	Uncharacterized protein.	RNase_PH domain-containing protein.	0.998
H2XJM9_CIOIN	LOC100182394	ENSCINP00000029861	ENSCINP00000026787	Uncharacterized protein.	Exosome complex component RRP4.	0.998
H2XJM9_CIOIN	LOC100187445	ENSCINP00000029861	ENSCINP00000024709	Uncharacterized protein.	Probable ATP-dependent RNA helicase DDX49 isoform X1; Belongs to the DEAD box helicase family.	0.673
H2XM17_CIOIN	F6VK85_CIOIN	ENSCINP00000030699	ENSCINP00000002868	FAT domain-containing protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.943
H2XM17_CIOIN	H2XWT8_CIOIN	ENSCINP00000030699	ENSCINP00000034122	FAT domain-containing protein.	Uncharacterized protein.	0.920
H2XM17_CIOIN	H2Y066_CIOIN	ENSCINP00000030699	ENSCINP00000035300	FAT domain-containing protein.	Uncharacterized protein.	0.964
H2XM17_CIOIN	LOC100176030	ENSCINP00000030699	ENSCINP00000001261	FAT domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.823
H2XR40_CIOIN	F7B6D7_CIOIN	ENSCINP00000032124	ENSCINP00000008384	RING-type domain-containing protein.	COMM domain-containing protein.	0.479