(9 nodes) HOPS complex network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100185122	Uncharacterized protein. (863 aa)
	LOC100181148	Syntaxin-17-like. (363 aa)
	F6Q2U2_CIOIN	CNH domain-containing protein. (871 aa)
	F6SZ37_CIOIN	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family. (844 aa)
	LOC100180059	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (626 aa)
	F6YU56_CIOIN	Uncharacterized protein. (351 aa)
	zf(ring)-20	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family. (841 aa)
	LOC100186755	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (598 aa)
	H2XX14_CIOIN	Uncharacterized protein. (116 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6Q2U2_CIOIN	F6SZ37_CIOIN	ENSCINP00000013314	ENSCINP00000014316	CNH domain-containing protein.	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	0.995
F6Q2U2_CIOIN	F6YU56_CIOIN	ENSCINP00000013314	ENSCINP00000026122	CNH domain-containing protein.	Uncharacterized protein.	0.914
F6Q2U2_CIOIN	H2XX14_CIOIN	ENSCINP00000013314	ENSCINP00000034198	CNH domain-containing protein.	Uncharacterized protein.	0.914
F6Q2U2_CIOIN	LOC100180059	ENSCINP00000013314	ENSCINP00000014583	CNH domain-containing protein.	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.	0.927
F6Q2U2_CIOIN	LOC100181148	ENSCINP00000013314	ENSCINP00000007118	CNH domain-containing protein.	Syntaxin-17-like.	0.937
F6Q2U2_CIOIN	LOC100185122	ENSCINP00000013314	ENSCINP00000000564	CNH domain-containing protein.	Uncharacterized protein.	0.994
F6Q2U2_CIOIN	LOC100186755	ENSCINP00000013314	ENSCINP00000030562	CNH domain-containing protein.	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.	0.970
F6Q2U2_CIOIN	zf(ring)-20	ENSCINP00000013314	ENSCINP00000026604	CNH domain-containing protein.	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	0.994
F6SZ37_CIOIN	F6Q2U2_CIOIN	ENSCINP00000014316	ENSCINP00000013314	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	CNH domain-containing protein.	0.995
F6SZ37_CIOIN	F6YU56_CIOIN	ENSCINP00000014316	ENSCINP00000026122	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	Uncharacterized protein.	0.954
F6SZ37_CIOIN	H2XX14_CIOIN	ENSCINP00000014316	ENSCINP00000034198	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	Uncharacterized protein.	0.954
F6SZ37_CIOIN	LOC100180059	ENSCINP00000014316	ENSCINP00000014583	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.	0.955
F6SZ37_CIOIN	LOC100181148	ENSCINP00000014316	ENSCINP00000007118	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	Syntaxin-17-like.	0.844
F6SZ37_CIOIN	LOC100185122	ENSCINP00000014316	ENSCINP00000000564	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	Uncharacterized protein.	0.997
F6SZ37_CIOIN	LOC100186755	ENSCINP00000014316	ENSCINP00000030562	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.	0.997
F6SZ37_CIOIN	zf(ring)-20	ENSCINP00000014316	ENSCINP00000026604	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	0.997
F6YU56_CIOIN	F6Q2U2_CIOIN	ENSCINP00000026122	ENSCINP00000013314	Uncharacterized protein.	CNH domain-containing protein.	0.914
F6YU56_CIOIN	F6SZ37_CIOIN	ENSCINP00000026122	ENSCINP00000014316	Uncharacterized protein.	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	0.954
F6YU56_CIOIN	H2XX14_CIOIN	ENSCINP00000026122	ENSCINP00000034198	Uncharacterized protein.	Uncharacterized protein.	0.798
F6YU56_CIOIN	LOC100180059	ENSCINP00000026122	ENSCINP00000014583	Uncharacterized protein.	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.	0.781