107 items (Ciona intestinalis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100178442	MATH domain-containing protein. (204 aa)
	H2XQZ1_CIOIN	Uncharacterized protein. (135 aa)
	H2XR40_CIOIN	RING-type domain-containing protein. (355 aa)
	LOC100175224	Ubiquitin-conjugating enzyme E2 A; Belongs to the ubiquitin-conjugating enzyme family. (156 aa)
	LOC100186591	Golgin-45. (382 aa)
	Cifrz	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (866 aa)
	F6YAC3_CIOIN	Senescence domain-containing protein. (116 aa)
	LOC100178496	CDK2-associated and cullin domain-containing protein 1; Belongs to the cullin family. (294 aa)
	LOC100179564	cAMP-dependent protein kinase type II regulatory subunit-like isoform X1. (394 aa)
	LOC100181381	UBX domain-containing protein. (367 aa)
	F6ZJN8_CIOIN	Uncharacterized protein. (381 aa)
	F6VXC2_CIOIN	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (262 aa)
	LOC100176093	Ubiquitin-conjugating enzyme E2 J1-like. (306 aa)
	LOC100177272	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1814 aa)
	LOC100177476	Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (251 aa)
	LOC100178394	F-box only protein 7. (515 aa)
	F6XRM1_CIOIN	Uncharacterized protein. (229 aa)
	F6WCU4_CIOIN	Uncharacterized protein. (954 aa)
	LOC100182334	Ubiquitin-conjugating enzyme E2 G1; Belongs to the ubiquitin-conjugating enzyme family. (167 aa)
	F6PKX1_CIOIN	ANK_REP_REGION domain-containing protein. (167 aa)
	F6PK54_CIOIN	Uncharacterized protein. (331 aa)
	smad6/7	Mothers against decapentaplegic homolog. (361 aa)
	LOC100186609	Uncharacterized protein; Belongs to the heat shock protein 70 family. (671 aa)
	F7AZD3_CIOIN	Glucose-6-phosphate isomerase; Belongs to the GPI family. (232 aa)
	LOC101242470	Uncharacterized protein; Belongs to the heat shock protein 70 family. (659 aa)
	psl3	Presenilin-like protein 3. (372 aa)
	F6R022_CIOIN	Uncharacterized protein. (309 aa)
	F6XI02_CIOIN	U-box domain-containing protein. (259 aa)
	LOC100186367	Gamma-aminobutyric acid receptor-associated protein. (117 aa)
	LOC100185283	Ras-related protein O-RAL isoform X2. (206 aa)
	LOC100184598	Sequestosome-1 isoform X1. (329 aa)
	F6VSS4_CIOIN	Uncharacterized protein. (350 aa)
	LOC100182606	Uncharacterized protein. (568 aa)
	H2XU53_CIOIN	Uncharacterized protein; Belongs to the heat shock protein 70 family. (643 aa)
	H2XUY6_CIOIN	Cullin_Nedd8 domain-containing protein; Belongs to the cullin family. (145 aa)
	LOC100175581	Uncharacterized protein LOC100175581. (186 aa)
	LOC100178793	OTU domain-containing protein. (296 aa)
	LOC100176962	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
	LOC100177695	Uncharacterized protein. (236 aa)
	LOC100178444	Microtubule-associated proteins 1A/1B light chain 3B-like. (121 aa)
	LOC100175446	Uncharacterized protein. (366 aa)
	H2Y1S8_CIOIN	CASPASE_P20 domain-containing protein; Belongs to the peptidase C14A family. (162 aa)
	LOC100185663	Vinculin. (1062 aa)
	H2Y2V4_CIOIN	Protein kinase domain-containing protein. (209 aa)
	H2Y3N0_CIOIN	UBA domain-containing protein. (90 aa)
	F7BMH5_CIOIN	UBX domain-containing protein. (447 aa)
	LOC100175152	Bis(5'-adenosyl)-triphosphatase. (154 aa)
	F6PMJ3_CIOIN	Uncharacterized protein. (219 aa)
	F6PWD4_CIOIN	SH3 domain-containing protein. (595 aa)
	F6ZXH0_CIOIN	Uncharacterized protein. (179 aa)
	F6SYE0_CIOIN	Protein kinase domain-containing protein. (216 aa)
	F6ZAH0_CIOIN	Uncharacterized protein. (382 aa)
	F6VJQ1_CIOIN	Uncharacterized protein. (347 aa)
	LOC100179623	TNF receptor-associated factor 3-like isoform X1. (351 aa)
	H2XJH2_CIOIN	Uncharacterized protein. (216 aa)
	H2XJH5_CIOIN	ANK_REP_REGION domain-containing protein. (95 aa)
	LOC100177760	FAS-associated factor 1-like. (168 aa)
	H2XL64_CIOIN	SMC_N domain-containing protein. (1036 aa)
	LOC100177728	Solute carrier family 22 member 18. (399 aa)
	H2XM66_CIOIN	E3 ubiquitin protein ligase. (985 aa)
	Q1RPY5_CIOIN	Zinc finger protein. (579 aa)
	H2XMI6_CIOIN	Uncharacterized protein. (1432 aa)
	H2XNP0_CIOIN	Uncharacterized protein. (243 aa)
	LOC100184136	JNK1/MAPK8-associated membrane protein. (316 aa)
	LOC104265386	Uncharacterized protein. (402 aa)
	F6UJ45_CIOIN	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (465 aa)
	F6T7F9_CIOIN	Uncharacterized protein. (480 aa)
	LOC100183130	CULLIN_2 domain-containing protein; Belongs to the cullin family. (744 aa)
	F6PP92_CIOIN	Uncharacterized protein; Belongs to the BI1 family. (241 aa)
	LOC100176571	Uncharacterized protein; Belongs to the ubiquitin-conjugating enzyme family. (198 aa)
	Axin	Uncharacterized protein. (643 aa)
	LOC100179599	Uncharacterized protein. (381 aa)
	F6YDG1_CIOIN	CULLIN_2 domain-containing protein; Belongs to the cullin family. (586 aa)
	LOC100184576	TNF receptor-associated factor 3-like. (290 aa)
	F6R472_CIOIN	CULLIN_2 domain-containing protein; Belongs to the cullin family. (707 aa)
	LOC100176246	Ubiquitin-like domain-containing protein. (78 aa)
	F6PKZ6_CIOIN	CULLIN_2 domain-containing protein; Belongs to the cullin family. (363 aa)
	F6PKS9_CIOIN	Cullin domain-containing protein; Belongs to the cullin family. (133 aa)
	LOC100175624	Ubiquitin-conjugating enzyme E2-17 kDa; Belongs to the ubiquitin-conjugating enzyme family. (148 aa)
	F7BPM3_CIOIN	UBX domain-containing protein. (342 aa)
	F7B5N7_CIOIN	Protein kinase domain-containing protein. (353 aa)
	LOC100178481	TNF receptor-associated factor 3. (369 aa)
	LOC100176290	Uncharacterized protein LOC100176290 isoform X4. (787 aa)
	LOC100176028	Erlin-1. (333 aa)
	F6YGJ7_CIOIN	Uncharacterized protein; Belongs to the peptidase C19 family. (1099 aa)
	F6UG35_CIOIN	Uncharacterized protein. (369 aa)
	Q1RLF0_CIOIN	Zinc finger protein (TRAF/RING)-2. (468 aa)
	LOC100179870	Peptidase_M24 domain-containing protein. (394 aa)
	zf(c2h2)-102	ATP-dependent DNA helicase II subunit 2; Single-stranded DNA-dependent ATP-dependent helicase. (706 aa)
	LOC100175110	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (254 aa)
	F7A9G9_CIOIN	RING-type domain-containing protein. (966 aa)
	LOC100186965	Ubiquitin-conjugating enzyme E2 L3-like isoform X1; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
	F6PMK8_CIOIN	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (710 aa)
	F6R982_CIOIN	WD_REPEATS_REGION domain-containing protein. (433 aa)
	F6WMB2_CIOIN	Uncharacterized protein. (524 aa)
	LOC100185384	ubiquitin-60S ribosomal protein L40. (128 aa)
	nemo-like	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (403 aa)
	LOC100181431	Uncharacterized protein. (535 aa)
	LOC100184540	Death domain-associated protein 6-like isoform X1. (234 aa)
	r27a	R27a protein isoform X1. (155 aa)
	LOC100176138	NADH-ubiquinone oxidoreductase 49 kDa subunit-like; Belongs to the complex I 49 kDa subunit family. (471 aa)
	F7BL69_CIOIN	WD_REPEATS_REGION domain-containing protein. (598 aa)
	F6PW28_CIOIN	CULLIN_2 domain-containing protein; Belongs to the cullin family. (778 aa)
	LOC100176009	cAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (367 aa)
	LOC100175879	CULLIN_2 domain-containing protein; Belongs to the cullin family. (614 aa)
	F6W9U8_CIOIN	PB1 domain-containing protein. (224 aa)
	F6VZ78_CIOIN	MATH domain-containing protein. (193 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Axin	Cifrz	ENSCINP00000005332	ENSCINP00000014064	Uncharacterized protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.508
Axin	F6PW28_CIOIN	ENSCINP00000005332	ENSCINP00000013359	Uncharacterized protein.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.656
Axin	F6R472_CIOIN	ENSCINP00000005332	ENSCINP00000006037	Uncharacterized protein.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.405
Axin	F6VJQ1_CIOIN	ENSCINP00000005332	ENSCINP00000026820	Uncharacterized protein.	Uncharacterized protein.	0.473
Axin	F6ZJN8_CIOIN	ENSCINP00000005332	ENSCINP00000015598	Uncharacterized protein.	Uncharacterized protein.	0.501
Axin	H2XUY6_CIOIN	ENSCINP00000005332	ENSCINP00000033470	Uncharacterized protein.	Cullin_Nedd8 domain-containing protein; Belongs to the cullin family.	0.405
Axin	nemo-like	ENSCINP00000005332	ENSCINP00000011009	Uncharacterized protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.491
Axin	r27a	ENSCINP00000005332	ENSCINP00000012037	Uncharacterized protein.	R27a protein isoform X1.	0.621
Cifrz	Axin	ENSCINP00000014064	ENSCINP00000005332	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein.	0.508
Cifrz	F6ZJN8_CIOIN	ENSCINP00000014064	ENSCINP00000015598	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein.	0.421
Cifrz	r27a	ENSCINP00000014064	ENSCINP00000012037	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	R27a protein isoform X1.	0.416
F6PK54_CIOIN	LOC100175224	ENSCINP00000018260	ENSCINP00000032379	Uncharacterized protein.	Ubiquitin-conjugating enzyme E2 A; Belongs to the ubiquitin-conjugating enzyme family.	0.464
F6PK54_CIOIN	LOC100175624	ENSCINP00000018260	ENSCINP00000007971	Uncharacterized protein.	Ubiquitin-conjugating enzyme E2-17 kDa; Belongs to the ubiquitin-conjugating enzyme family.	0.461
F6PK54_CIOIN	LOC100176093	ENSCINP00000018260	ENSCINP00000015709	Uncharacterized protein.	Ubiquitin-conjugating enzyme E2 J1-like.	0.461
F6PK54_CIOIN	LOC100176571	ENSCINP00000018260	ENSCINP00000004770	Uncharacterized protein.	Uncharacterized protein; Belongs to the ubiquitin-conjugating enzyme family.	0.461
F6PK54_CIOIN	LOC100176962	ENSCINP00000018260	ENSCINP00000034116	Uncharacterized protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.461
F6PK54_CIOIN	LOC100182334	ENSCINP00000018260	ENSCINP00000017801	Uncharacterized protein.	Ubiquitin-conjugating enzyme E2 G1; Belongs to the ubiquitin-conjugating enzyme family.	0.476
F6PK54_CIOIN	LOC100186965	ENSCINP00000018260	ENSCINP00000009617	Uncharacterized protein.	Ubiquitin-conjugating enzyme E2 L3-like isoform X1; Belongs to the ubiquitin-conjugating enzyme family.	0.461
F6PKS9_CIOIN	F6PKZ6_CIOIN	ENSCINP00000006260	ENSCINP00000006254	Cullin domain-containing protein; Belongs to the cullin family.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.918
F6PKS9_CIOIN	F6PW28_CIOIN	ENSCINP00000006260	ENSCINP00000013359	Cullin domain-containing protein; Belongs to the cullin family.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.857