(20 nodes) Negative regulation of telomere maintenance network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	F6RJ65_CIOIN	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (268 aa)
	F6RZ99_CIOIN	Zinc-hook domain-containing protein. (477 aa)
	F6RYY5_CIOIN	AAA_23 domain-containing protein. (400 aa)
	F6R4R6_CIOIN	HRDC domain-containing protein. (292 aa)
	F6UD77_CIOIN	ANK_REP_REGION domain-containing protein. (538 aa)
	PIF1	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (607 aa)
	F6Y8C3_CIOIN	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires a tRNA-binding adapter protein for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (956 aa)
	F6SK60_CIOIN	Uncharacterized protein. (372 aa)
	F6PIQ0_CIOIN	PINc domain-containing protein. (485 aa)
	F6YY15_CIOIN	ERCC4 domain-containing protein. (826 aa)
	F6VBZ6_CIOIN	Telo_bind domain-containing protein. (527 aa)
	H2XK76_CIOIN	Poly [ADP-ribose] polymerase. (375 aa)
	H2XNU2_CIOIN	Uncharacterized protein. (214 aa)
	H2XU97_CIOIN	HRDC domain-containing protein. (194 aa)
	LOC100184449	PIN2/TERF1-interacting telomerase inhibitor 1-like. (260 aa)
	H2XWR8_CIOIN	Nudix hydrolase domain-containing protein. (235 aa)
	H2XYT6_CIOIN	3'-5' exonuclease domain-containing protein. (261 aa)
	H2Y2T2_CIOIN	FAT domain-containing protein. (235 aa)
	H2Y3J0_CIOIN	Uncharacterized protein. (176 aa)
	LOC100183893	Uncharacterized protein. (480 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6PIQ0_CIOIN	H2Y3J0_CIOIN	ENSCINP00000020219	ENSCINP00000036475	PINc domain-containing protein.	Uncharacterized protein.	0.961
F6R4R6_CIOIN	H2XU97_CIOIN	ENSCINP00000004852	ENSCINP00000033231	HRDC domain-containing protein.	HRDC domain-containing protein.	0.554
F6R4R6_CIOIN	H2XYT6_CIOIN	ENSCINP00000004852	ENSCINP00000034820	HRDC domain-containing protein.	3'-5' exonuclease domain-containing protein.	0.904
F6RJ65_CIOIN	F6RYY5_CIOIN	ENSCINP00000001490	ENSCINP00000003245	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	AAA_23 domain-containing protein.	0.707
F6RJ65_CIOIN	F6RZ99_CIOIN	ENSCINP00000001490	ENSCINP00000003235	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Zinc-hook domain-containing protein.	0.707
F6RJ65_CIOIN	F6SK60_CIOIN	ENSCINP00000001490	ENSCINP00000010637	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.454
F6RJ65_CIOIN	F6YY15_CIOIN	ENSCINP00000001490	ENSCINP00000024251	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	ERCC4 domain-containing protein.	0.474
F6RJ65_CIOIN	H2XNU2_CIOIN	ENSCINP00000001490	ENSCINP00000031325	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.707
F6RJ65_CIOIN	H2Y2T2_CIOIN	ENSCINP00000001490	ENSCINP00000036217	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	FAT domain-containing protein.	0.949
F6RYY5_CIOIN	F6RJ65_CIOIN	ENSCINP00000003245	ENSCINP00000001490	AAA_23 domain-containing protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.707
F6RYY5_CIOIN	F6RZ99_CIOIN	ENSCINP00000003245	ENSCINP00000003235	AAA_23 domain-containing protein.	Zinc-hook domain-containing protein.	0.900
F6RYY5_CIOIN	H2XNU2_CIOIN	ENSCINP00000003245	ENSCINP00000031325	AAA_23 domain-containing protein.	Uncharacterized protein.	0.971
F6RYY5_CIOIN	H2Y2T2_CIOIN	ENSCINP00000003245	ENSCINP00000036217	AAA_23 domain-containing protein.	FAT domain-containing protein.	0.707
F6RYY5_CIOIN	LOC100183893	ENSCINP00000003245	ENSCINP00000036521	AAA_23 domain-containing protein.	Uncharacterized protein.	0.499
F6RYY5_CIOIN	PIF1	ENSCINP00000003245	ENSCINP00000005776	AAA_23 domain-containing protein.	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.	0.546
F6RZ99_CIOIN	F6RJ65_CIOIN	ENSCINP00000003235	ENSCINP00000001490	Zinc-hook domain-containing protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.707
F6RZ99_CIOIN	F6RYY5_CIOIN	ENSCINP00000003235	ENSCINP00000003245	Zinc-hook domain-containing protein.	AAA_23 domain-containing protein.	0.900
F6RZ99_CIOIN	H2XNU2_CIOIN	ENSCINP00000003235	ENSCINP00000031325	Zinc-hook domain-containing protein.	Uncharacterized protein.	0.900
F6RZ99_CIOIN	H2Y2T2_CIOIN	ENSCINP00000003235	ENSCINP00000036217	Zinc-hook domain-containing protein.	FAT domain-containing protein.	0.707
F6RZ99_CIOIN	LOC100183893	ENSCINP00000003235	ENSCINP00000036521	Zinc-hook domain-containing protein.	Uncharacterized protein.	0.499