(18 nodes) Endosome transport via multivesicular body sorting pathway network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100182764	Charged multivesicular body protein 5. (217 aa)
	LOC100183691	Transmembrane protein 50B-like. (160 aa)
	H2XUB7_CIOIN	Sortilin-Vps10 domain-containing protein. (205 aa)
	LOC100186306	UBX domain-containing protein. (412 aa)
	H2XSV3_CIOIN	Sortilin-Vps10 domain-containing protein. (276 aa)
	LOC104266244	Vacuolar protein sorting-associated protein VTA1 homolog. (291 aa)
	H2XPM9_CIOIN	Uncharacterized protein. (209 aa)
	LOC100177673	Vacuolar protein-sorting-associated protein 25. (176 aa)
	LOC100185572	Charged multivesicular body protein 4b-like isoform X1. (217 aa)
	LOC100180662	Charged multivesicular body protein 6-B-like. (204 aa)
	F6ZFT6_CIOIN	Uncharacterized protein. (454 aa)
	F6XUK1_CIOIN	Uncharacterized protein. (211 aa)
	LOC100178975	Charged multivesicular body protein 2a-like. (222 aa)
	F6PHZ4_CIOIN	Uncharacterized protein. (266 aa)
	LOC100182534	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (208 aa)
	LOC100187157	Uncharacterized protein; Belongs to the AAA ATPase family. (811 aa)
	LOC100176704	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (248 aa)
	F7AQ24_CIOIN	Uncharacterized protein. (323 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6PHZ4_CIOIN	F6XUK1_CIOIN	ENSCINP00000020279	ENSCINP00000022775	Uncharacterized protein.	Uncharacterized protein.	0.666
F6PHZ4_CIOIN	F6ZFT6_CIOIN	ENSCINP00000020279	ENSCINP00000024521	Uncharacterized protein.	Uncharacterized protein.	0.540
F6PHZ4_CIOIN	F7AQ24_CIOIN	ENSCINP00000020279	ENSCINP00000010164	Uncharacterized protein.	Uncharacterized protein.	0.912
F6PHZ4_CIOIN	H2XPM9_CIOIN	ENSCINP00000020279	ENSCINP00000031613	Uncharacterized protein.	Uncharacterized protein.	0.698
F6PHZ4_CIOIN	LOC100176704	ENSCINP00000020279	ENSCINP00000012524	Uncharacterized protein.	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family.	0.905
F6PHZ4_CIOIN	LOC100177673	ENSCINP00000020279	ENSCINP00000031552	Uncharacterized protein.	Vacuolar protein-sorting-associated protein 25.	0.917
F6PHZ4_CIOIN	LOC100178975	ENSCINP00000020279	ENSCINP00000021747	Uncharacterized protein.	Charged multivesicular body protein 2a-like.	0.775
F6PHZ4_CIOIN	LOC100180662	ENSCINP00000020279	ENSCINP00000026802	Uncharacterized protein.	Charged multivesicular body protein 6-B-like.	0.795
F6PHZ4_CIOIN	LOC100182534	ENSCINP00000020279	ENSCINP00000020236	Uncharacterized protein.	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.	0.918
F6PHZ4_CIOIN	LOC100185572	ENSCINP00000020279	ENSCINP00000029641	Uncharacterized protein.	Charged multivesicular body protein 4b-like isoform X1.	0.769
F6PHZ4_CIOIN	LOC104266244	ENSCINP00000020279	ENSCINP00000031885	Uncharacterized protein.	Vacuolar protein sorting-associated protein VTA1 homolog.	0.519
F6XUK1_CIOIN	F6PHZ4_CIOIN	ENSCINP00000022775	ENSCINP00000020279	Uncharacterized protein.	Uncharacterized protein.	0.666
F6XUK1_CIOIN	F6ZFT6_CIOIN	ENSCINP00000022775	ENSCINP00000024521	Uncharacterized protein.	Uncharacterized protein.	0.862
F6XUK1_CIOIN	H2XPM9_CIOIN	ENSCINP00000022775	ENSCINP00000031613	Uncharacterized protein.	Uncharacterized protein.	0.964
F6XUK1_CIOIN	LOC100176704	ENSCINP00000022775	ENSCINP00000012524	Uncharacterized protein.	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family.	0.818
F6XUK1_CIOIN	LOC100177673	ENSCINP00000022775	ENSCINP00000031552	Uncharacterized protein.	Vacuolar protein-sorting-associated protein 25.	0.845
F6XUK1_CIOIN	LOC100178975	ENSCINP00000022775	ENSCINP00000021747	Uncharacterized protein.	Charged multivesicular body protein 2a-like.	0.982
F6XUK1_CIOIN	LOC100180662	ENSCINP00000022775	ENSCINP00000026802	Uncharacterized protein.	Charged multivesicular body protein 6-B-like.	0.879
F6XUK1_CIOIN	LOC100182534	ENSCINP00000022775	ENSCINP00000020236	Uncharacterized protein.	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.	0.845
F6XUK1_CIOIN	LOC100182764	ENSCINP00000022775	ENSCINP00000009854	Uncharacterized protein.	Charged multivesicular body protein 5.	0.617