125 items (Ciona intestinalis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	F6WGY1_CIOIN	Structure-specific endonuclease subunit SLX1 homolog; Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA; Belongs to the SLX1 family. (246 aa)
	LOC100180482	Structural maintenance of chromosomes protein. (1202 aa)
	F6SFA7_CIOIN	Uncharacterized protein. (230 aa)
	F6ZE60_CIOIN	ANAPC4 domain-containing protein. (494 aa)
	F6Q3X3_CIOIN	Fibronectin type-III domain-containing protein. (173 aa)
	F6RJ65_CIOIN	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (268 aa)
	LOC100175935	Ubiquitin carboxyl-terminal hydrolase. (328 aa)
	F6WB99_CIOIN	Uncharacterized protein. (401 aa)
	F7AE79_CIOIN	SP-RING-type domain-containing protein. (239 aa)
	Sir2-d	Deacetylase sirtuin-type domain-containing protein. (91 aa)
	F6W7K5_CIOIN	T-complex protein 1 subunit gamma. (530 aa)
	LOC100181285	T-complex protein 1 subunit gamma. (543 aa)
	F6TI28_CIOIN	Mitogen-activated protein kinase. (364 aa)
	F6RZ99_CIOIN	Zinc-hook domain-containing protein. (477 aa)
	F6RYY5_CIOIN	AAA_23 domain-containing protein. (400 aa)
	LOC100182084	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (461 aa)
	F6W6K0_CIOIN	Uncharacterized protein. (534 aa)
	F6RA65_CIOIN	RIO domain-containing protein. (504 aa)
	F6R4R6_CIOIN	HRDC domain-containing protein. (292 aa)
	F6YDG1_CIOIN	CULLIN_2 domain-containing protein; Belongs to the cullin family. (586 aa)
	F6UD77_CIOIN	ANK_REP_REGION domain-containing protein. (538 aa)
	PIF1	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (607 aa)
	Mapkk7	Protein kinase domain-containing protein. (478 aa)
	F6R472_CIOIN	CULLIN_2 domain-containing protein; Belongs to the cullin family. (707 aa)
	LOC100182930	Centromere protein V-like. (142 aa)
	F6PL57_CIOIN	Uncharacterized protein. (1087 aa)
	F6Z4B6_CIOIN	Uncharacterized protein. (758 aa)
	F6WYC4_CIOIN	TFIIS N-terminal domain-containing protein. (494 aa)
	F6Y8C3_CIOIN	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires a tRNA-binding adapter protein for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (956 aa)
	F7ADN1_CIOIN	Structural maintenance of chromosomes protein. (1253 aa)
	F6TV58_CIOIN	Uncharacterized protein. (147 aa)
	zf(c2h2)-102	ATP-dependent DNA helicase II subunit 2; Single-stranded DNA-dependent ATP-dependent helicase. (706 aa)
	F6U2M6_CIOIN	PUA domain-containing protein. (528 aa)
	LOC100177411	RuvB-like helicase; Belongs to the RuvB family. (467 aa)
	F6PLM3_CIOIN	Bromo domain-containing protein. (295 aa)
	LOC100176899	Protein kinase domain-containing protein. (658 aa)
	myc	Transcription factor protein isoform X1. (681 aa)
	F6SK60_CIOIN	Uncharacterized protein. (372 aa)
	LOC100185398	Actin-like protein 6B; Belongs to the actin family. (423 aa)
	Zf(cxxc)-5	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1257 aa)
	LOC100181431	Uncharacterized protein. (535 aa)
	LOC100176070	Mitotic spindle assembly checkpoint protein MAD1. (714 aa)
	F6WQ08_CIOIN	Protein kinase domain-containing protein. (473 aa)
	F6SED5_CIOIN	Uncharacterized protein. (211 aa)
	zf(c2h2)-28	Zinc finger protein isoform X1. (327 aa)
	F6QSH0_CIOIN	Uncharacterized protein. (709 aa)
	LOC100182651	E3 ubiquitin-protein ligase RNF4 isoform X1. (224 aa)
	LOC100182501	TPR_REGION domain-containing protein. (560 aa)
	Cibeta-catenin	Uncharacterized protein. (497 aa)
	F6XWY9_CIOIN	TPR_REGION domain-containing protein. (823 aa)
	LOC100183329	ULP_PROTEASE domain-containing protein. (387 aa)
	F6W6L5_CIOIN	MCM domain-containing protein; Belongs to the MCM family. (422 aa)
	F6W685_CIOIN	Uncharacterized protein. (428 aa)
	F6THB4_CIOIN	Uncharacterized protein. (181 aa)
	F6SSU2_CIOIN	TPR_REGION domain-containing protein. (387 aa)
	F6S4U2_CIOIN	CP-type G domain-containing protein. (538 aa)
	LOC100181789	AAA_23 domain-containing protein. (1070 aa)
	zf(ring)-55	Zinc finger protein. (323 aa)
	LOC100179672	Serine/threonine-protein kinase Nek7-like; Belongs to the protein kinase superfamily. (288 aa)
	LOC100182716	Flap endonuclease GEN homolog 1. (709 aa)
	LOC100176488	T-complex protein 1 subunit delta. (540 aa)
	F6WCU4_CIOIN	Uncharacterized protein. (954 aa)
	F6T120_CIOIN	TPR_REGION domain-containing protein. (357 aa)
	LOC100180348	B-cell CLL/lymphoma 7 protein family member B-like. (167 aa)
	LOC100186474	Uncharacterized protein LOC100186474 isoform X1. (164 aa)
	LOC100181478	T-complex protein 1 subunit epsilon-like. (538 aa)
	LOC100183428	Uncharacterized protein. (786 aa)
	F6PKV2_CIOIN	UBIQUITIN_CONJUGAT_2 domain-containing protein. (144 aa)
	LOC100176733	Cnd3 domain-containing protein. (957 aa)
	F6UX10_CIOIN	DNA_LIGASE_A3 domain-containing protein; Belongs to the ATP-dependent DNA ligase family. (655 aa)
	F6SXS1_CIOIN	Uncharacterized protein. (932 aa)
	LOC100186469	WD_REPEATS_REGION domain-containing protein. (338 aa)
	F6PIQ0_CIOIN	PINc domain-containing protein. (485 aa)
	F6XGY9_CIOIN	Uncharacterized protein. (373 aa)
	LOC100179562	Uncharacterized protein. (603 aa)
	F7ABN7_CIOIN	F-box domain-containing protein. (241 aa)
	LOC100182525	Uncharacterized protein. (461 aa)
	F6XCT9_CIOIN	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (256 aa)
	F6YY15_CIOIN	ERCC4 domain-containing protein. (826 aa)
	F6PWP3_CIOIN	Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. (1233 aa)
	F6TE72_CIOIN	Protein kinase domain-containing protein. (172 aa)
	F6SQW7_CIOIN	Uncharacterized protein. (328 aa)
	F6UNB7_CIOIN	ANAPC5 domain-containing protein. (294 aa)
	F6TZA7_CIOIN	Uncharacterized protein. (273 aa)
	F6VBZ6_CIOIN	Telo_bind domain-containing protein. (527 aa)
	F6Y252_CIOIN	GN3L_Grn1 domain-containing protein. (71 aa)
	F6PNC3_CIOIN	Uncharacterized protein. (1086 aa)
	nfrkb	Uncharacterized protein. (310 aa)
	LOC100178070	Uncharacterized protein. (347 aa)
	F6X0L7_CIOIN	FHA_2 domain-containing protein. (571 aa)
	H2XJH5_CIOIN	ANK_REP_REGION domain-containing protein. (95 aa)
	H2XJT4_CIOIN	PHD-type domain-containing protein. (508 aa)
	H2XK76_CIOIN	Poly [ADP-ribose] polymerase. (375 aa)
	H2XMY5_CIOIN	Uncharacterized protein. (281 aa)
	H2XN24_CIOIN	PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family. (158 aa)
	H2XNN7_CIOIN	Uncharacterized protein. (112 aa)
	H2XNP0_CIOIN	Uncharacterized protein. (243 aa)
	H2XNU2_CIOIN	Uncharacterized protein. (214 aa)
	H2XNU4_CIOIN	Uncharacterized protein. (530 aa)
	H2XP61_CIOIN	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (236 aa)
	H2XQK9_CIOIN	Uncharacterized protein. (836 aa)
	H2XR98_CIOIN	Protein kinase domain-containing protein. (365 aa)
	H2XR99_CIOIN	FHA domain-containing protein. (427 aa)
	H2XRB3_CIOIN	Uncharacterized protein. (548 aa)
	H2XRK6_CIOIN	HORMA domain-containing protein. (87 aa)
	H2XTG3_CIOIN	Uncharacterized protein. (233 aa)
	H2XU97_CIOIN	HRDC domain-containing protein. (194 aa)
	LOC100184078	CDT1 domain-containing protein. (407 aa)
	H2XUY6_CIOIN	Cullin_Nedd8 domain-containing protein; Belongs to the cullin family. (145 aa)
	H2XV25_CIOIN	Uncharacterized protein. (652 aa)
	H2XVA8_CIOIN	Uncharacterized protein. (53 aa)
	H2XVQ7_CIOIN	WAPL domain-containing protein. (196 aa)
	LOC100184449	PIN2/TERF1-interacting telomerase inhibitor 1-like. (260 aa)
	H2XWH9_CIOIN	Protein kinase domain-containing protein. (203 aa)
	H2XWR8_CIOIN	Nudix hydrolase domain-containing protein. (235 aa)
	H2XWV3_CIOIN	Rod_C domain-containing protein. (792 aa)
	H2XXJ7_CIOIN	Uncharacterized protein. (347 aa)
	H2XYT6_CIOIN	3'-5' exonuclease domain-containing protein. (261 aa)
	H2XZ46_CIOIN	Uncharacterized protein. (108 aa)
	H2Y0G1_CIOIN	Protein kinase domain-containing protein. (526 aa)
	H2Y0W5_CIOIN	FATC domain-containing protein. (201 aa)
	H2Y2T2_CIOIN	FAT domain-containing protein. (235 aa)
	LOC100185658	Kinetochore protein NDC80 homolog. (596 aa)
	H2Y3J0_CIOIN	Uncharacterized protein. (176 aa)
	LOC100183893	Uncharacterized protein. (480 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cibeta-catenin	F6R472_CIOIN	ENSCINP00000014417	ENSCINP00000006037	Uncharacterized protein.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.481
Cibeta-catenin	F6TZA7_CIOIN	ENSCINP00000014417	ENSCINP00000025972	Uncharacterized protein.	Uncharacterized protein.	0.963
Cibeta-catenin	H2XUY6_CIOIN	ENSCINP00000014417	ENSCINP00000033470	Uncharacterized protein.	Cullin_Nedd8 domain-containing protein; Belongs to the cullin family.	0.459
Cibeta-catenin	LOC100177411	ENSCINP00000014417	ENSCINP00000009659	Uncharacterized protein.	RuvB-like helicase; Belongs to the RuvB family.	0.696
F6PIQ0_CIOIN	F6WCU4_CIOIN	ENSCINP00000020219	ENSCINP00000017766	PINc domain-containing protein.	Uncharacterized protein.	0.894
F6PIQ0_CIOIN	H2XMY5_CIOIN	ENSCINP00000020219	ENSCINP00000031018	PINc domain-containing protein.	Uncharacterized protein.	0.444
F6PIQ0_CIOIN	H2XQK9_CIOIN	ENSCINP00000020219	ENSCINP00000031943	PINc domain-containing protein.	Uncharacterized protein.	0.821
F6PIQ0_CIOIN	H2XV25_CIOIN	ENSCINP00000020219	ENSCINP00000033509	PINc domain-containing protein.	Uncharacterized protein.	0.444
F6PIQ0_CIOIN	H2Y0W5_CIOIN	ENSCINP00000020219	ENSCINP00000035549	PINc domain-containing protein.	FATC domain-containing protein.	0.444
F6PIQ0_CIOIN	H2Y3J0_CIOIN	ENSCINP00000020219	ENSCINP00000036475	PINc domain-containing protein.	Uncharacterized protein.	0.961
F6PIQ0_CIOIN	zf(c2h2)-102	ENSCINP00000020219	ENSCINP00000009339	PINc domain-containing protein.	ATP-dependent DNA helicase II subunit 2; Single-stranded DNA-dependent ATP-dependent helicase.	0.440
F6PKV2_CIOIN	F6PWP3_CIOIN	ENSCINP00000018235	ENSCINP00000025038	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.	0.419
F6PKV2_CIOIN	F6QSH0_CIOIN	ENSCINP00000018235	ENSCINP00000013216	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Uncharacterized protein.	0.536
F6PKV2_CIOIN	F6SSU2_CIOIN	ENSCINP00000018235	ENSCINP00000016408	UBIQUITIN_CONJUGAT_2 domain-containing protein.	TPR_REGION domain-containing protein.	0.975
F6PKV2_CIOIN	F6UNB7_CIOIN	ENSCINP00000018235	ENSCINP00000025938	UBIQUITIN_CONJUGAT_2 domain-containing protein.	ANAPC5 domain-containing protein.	0.948
F6PKV2_CIOIN	F6XCT9_CIOIN	ENSCINP00000018235	ENSCINP00000023720	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.590
F6PKV2_CIOIN	F6XGY9_CIOIN	ENSCINP00000018235	ENSCINP00000021930	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Uncharacterized protein.	0.850
F6PKV2_CIOIN	F6XWY9_CIOIN	ENSCINP00000018235	ENSCINP00000015343	UBIQUITIN_CONJUGAT_2 domain-containing protein.	TPR_REGION domain-containing protein.	0.962
F6PKV2_CIOIN	F6YDG1_CIOIN	ENSCINP00000018235	ENSCINP00000005419	UBIQUITIN_CONJUGAT_2 domain-containing protein.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.974
F6PKV2_CIOIN	F6ZE60_CIOIN	ENSCINP00000018235	ENSCINP00000000838	UBIQUITIN_CONJUGAT_2 domain-containing protein.	ANAPC4 domain-containing protein.	0.976