(78 nodes) Ribonucleoside bisphosphate metabolic process network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	elo	Elongation of very long chain fatty acids protein. (289 aa)
	F6VXM0_CIOIN	Uncharacterized protein. (362 aa)
	LOC100176701	Elongation of very long chain fatty acids protein. (272 aa)
	F7BBJ9_CIOIN	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (357 aa)
	F7BBK7_CIOIN	DAO domain-containing protein. (124 aa)
	F6QJB5_CIOIN	HD domain-containing protein. (179 aa)
	F6PK80_CIOIN	Aminotran_1_2 domain-containing protein. (432 aa)
	F6SZU4_CIOIN	AMP-binding domain-containing protein. (640 aa)
	LOC100185939	AMP-binding domain-containing protein. (702 aa)
	F6T0F1_CIOIN	Uncharacterized protein. (2241 aa)
	F7AHK9_CIOIN	CoA carboxyltransferase N-terminal domain-containing protein. (488 aa)
	LOC100187386	Phosphopantothenate--cysteine ligase-like. (281 aa)
	F6T7H6_CIOIN	CTP_transf_like domain-containing protein. (560 aa)
	F6YIX5_CIOIN	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (476 aa)
	LOC100184407	Uncharacterized protein. (283 aa)
	LOC100182241	Protein PLANT CADMIUM RESISTANCE 2-like. (110 aa)
	F6TS86_CIOIN	Carn_acyltransf domain-containing protein. (603 aa)
	H2Y3N5_CIOIN	Bile_Hydr_Trans domain-containing protein. (250 aa)
	H2Y2K4_CIOIN	3-hydroxy-3-methylglutaryl coenzyme A reductase. (807 aa)
	H2XZP2_CIOIN	PlsC domain-containing protein. (185 aa)
	H2XZC9_CIOIN	Aminotran_1_2 domain-containing protein. (425 aa)
	H2XYN5_CIOIN	Acetyl-coenzyme A synthetase. (633 aa)
	H2XYI4_CIOIN	Citrate_bind domain-containing protein. (84 aa)
	H2XY83_CIOIN	Uncharacterized protein. (445 aa)
	H2XXG5_CIOIN	AlaDh_PNT_N domain-containing protein. (215 aa)
	H2XX20_CIOIN	Uncharacterized protein. (106 aa)
	H2XW59_CIOIN	Uncharacterized protein. (197 aa)
	H2XTF1_CIOIN	Mevalonate kinase. (331 aa)
	H2XTC8_CIOIN	MaoC-like domain-containing protein. (133 aa)
	Acl	ATP-grasp_2 domain-containing protein. (250 aa)
	H2XR58_CIOIN	Uncharacterized protein. (233 aa)
	H2XQG7_CIOIN	VOC domain-containing protein. (177 aa)
	LOC100176146	Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (125 aa)
	H2XM65_CIOIN	Uncharacterized protein. (105 aa)
	LOC100182900	Elongation of very long chain fatty acids protein. (290 aa)
	F7BH52_CIOIN	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (508 aa)
	F6WVH9_CIOIN	Amine oxidase. (396 aa)
	LOC100181631	Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (412 aa)
	F6VDE1_CIOIN	Uncharacterized protein. (417 aa)
	F6VDF0_CIOIN	Bile_Hydr_Trans domain-containing protein. (240 aa)
	F6VDG2_CIOIN	Bile_Hydr_Trans domain-containing protein. (126 aa)
	F6VDH1_CIOIN	Bile_Hydr_Trans domain-containing protein. (183 aa)
	F6VDJ9_CIOIN	Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (507 aa)
	F6VDW8_CIOIN	Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (530 aa)
	F6PML6_CIOIN	Nudix hydrolase domain-containing protein. (230 aa)
	F6YW02_CIOIN	DAO domain-containing protein. (363 aa)
	F6ZGJ4_CIOIN	Uncharacterized protein. (388 aa)
	LOC100185392	Phosphopantothenoylcysteine decarboxylase-like. (188 aa)
	F6U5F1_CIOIN	Ligase_CoA domain-containing protein. (404 aa)
	F6TU49_CIOIN	Uncharacterized protein. (540 aa)
	F6TAH1_CIOIN	DAO domain-containing protein. (152 aa)
	F6SPL5_CIOIN	Elongation of very long chain fatty acids protein. (173 aa)
	F6T0R8_CIOIN	Uncharacterized protein. (67 aa)
	LOC100175450	DAO domain-containing protein. (299 aa)
	LOC100183557	DAO domain-containing protein. (312 aa)
	LOC100187068	Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (123 aa)
	F6ZU97_CIOIN	Uncharacterized protein. (460 aa)
	LOC100181141	Uncharacterized protein. (575 aa)
	LOC100184237	Elongation of very long chain fatty acids protein. (279 aa)
	LOC100187421	Peroxisomal multifunctional enzyme type 2. (720 aa)
	asak	ATP sulfurylase/APS kinase isoform X1. (618 aa)
	F7B0S6_CIOIN	Acetyl-coenzyme A synthetase. (667 aa)
	LOC100186020	Elongation of very long chain fatty acids protein. (275 aa)
	LOC100185366	Cell number regulator 10 isoform X1. (115 aa)
	LOC100178841	3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (443 aa)
	LOC100179153	Uncharacterized protein. (418 aa)
	F6X5M5_CIOIN	Uncharacterized protein. (400 aa)
	LOC100184967	Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (432 aa)
	F6VL03_CIOIN	Elongation of very long chain fatty acids protein. (256 aa)
	LOC100175295	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (501 aa)
	F7AZV0_CIOIN	Lipoyl-binding domain-containing protein. (391 aa)
	LOC100177655	Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial-like isoform X4. (432 aa)
	L7N0S9_CIOIN	Aminotran_1_2 domain-containing protein. (219 aa)
	LOC100184635	Uncharacterized protein. (401 aa)
	F6YXK3_CIOIN	Uncharacterized protein. (326 aa)
	LOC100183815	Peroxisomal sarcosine oxidase-like isoform X3. (393 aa)
	LOC100184477	Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (385 aa)
	F6Z0U1_CIOIN	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. (380 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Acl	F6T0F1_CIOIN	ENSCINP00000032586	ENSCINP00000005865	ATP-grasp_2 domain-containing protein.	Uncharacterized protein.	0.885
Acl	F6T7H6_CIOIN	ENSCINP00000032586	ENSCINP00000003735	ATP-grasp_2 domain-containing protein.	CTP_transf_like domain-containing protein.	0.431
Acl	F6U5F1_CIOIN	ENSCINP00000032586	ENSCINP00000023291	ATP-grasp_2 domain-containing protein.	Ligase_CoA domain-containing protein.	0.949
Acl	F6YIX5_CIOIN	ENSCINP00000032586	ENSCINP00000003336	ATP-grasp_2 domain-containing protein.	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.660
Acl	F7AZV0_CIOIN	ENSCINP00000032586	ENSCINP00000014023	ATP-grasp_2 domain-containing protein.	Lipoyl-binding domain-containing protein.	0.665
Acl	F7BH52_CIOIN	ENSCINP00000032586	ENSCINP00000026648	ATP-grasp_2 domain-containing protein.	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.675
Acl	H2XM65_CIOIN	ENSCINP00000032586	ENSCINP00000030747	ATP-grasp_2 domain-containing protein.	Uncharacterized protein.	0.949
Acl	H2XYI4_CIOIN	ENSCINP00000032586	ENSCINP00000034718	ATP-grasp_2 domain-containing protein.	Citrate_bind domain-containing protein.	0.464
Acl	LOC100175295	ENSCINP00000032586	ENSCINP00000014459	ATP-grasp_2 domain-containing protein.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.833
Acl	asak	ENSCINP00000032586	ENSCINP00000018567	ATP-grasp_2 domain-containing protein.	ATP sulfurylase/APS kinase isoform X1.	0.431
F6PK80_CIOIN	F7AZV0_CIOIN	ENSCINP00000006285	ENSCINP00000014023	Aminotran_1_2 domain-containing protein.	Lipoyl-binding domain-containing protein.	0.908
F6PK80_CIOIN	L7N0S9_CIOIN	ENSCINP00000006285	ENSCINP00000013525	Aminotran_1_2 domain-containing protein.	Aminotran_1_2 domain-containing protein.	0.906
F6PML6_CIOIN	F6T7H6_CIOIN	ENSCINP00000025078	ENSCINP00000003735	Nudix hydrolase domain-containing protein.	CTP_transf_like domain-containing protein.	0.591
F6PML6_CIOIN	LOC100184407	ENSCINP00000025078	ENSCINP00000001072	Nudix hydrolase domain-containing protein.	Uncharacterized protein.	0.477
F6SPL5_CIOIN	F6T0F1_CIOIN	ENSCINP00000022049	ENSCINP00000005865	Elongation of very long chain fatty acids protein.	Uncharacterized protein.	0.452
F6SPL5_CIOIN	LOC100178841	ENSCINP00000022049	ENSCINP00000016402	Elongation of very long chain fatty acids protein.	3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	0.900
F6SPL5_CIOIN	LOC100182900	ENSCINP00000022049	ENSCINP00000028199	Elongation of very long chain fatty acids protein.	Elongation of very long chain fatty acids protein.	0.902
F6SZU4_CIOIN	F6T0F1_CIOIN	ENSCINP00000005887	ENSCINP00000005865	AMP-binding domain-containing protein.	Uncharacterized protein.	0.409
F6SZU4_CIOIN	H2XTC8_CIOIN	ENSCINP00000005887	ENSCINP00000032912	AMP-binding domain-containing protein.	MaoC-like domain-containing protein.	0.656
F6SZU4_CIOIN	LOC100184635	ENSCINP00000005887	ENSCINP00000013343	AMP-binding domain-containing protein.	Uncharacterized protein.	0.463