(23 nodes) Regulation of transcription elongation from RNA polymerase II promoter network (Ciona intestinalis)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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Your Input:
	F6SJH8_CIOIN	S1 motif domain-containing protein. (450 aa)
	F6SJ61_CIOIN	HTH_44 domain-containing protein. (505 aa)
	LOC100185508	WD repeat-containing protein 43. (630 aa)
	LOC494392	Uncharacterized protein LOC494392. (131 aa)
	LOC100183995	Uncharacterized protein. (575 aa)
	Sir2-d	Deacetylase sirtuin-type domain-containing protein. (91 aa)
	F6X618_CIOIN	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (515 aa)
	LOC100187074	Uncharacterized protein. (549 aa)
	LOC100183139	Uncharacterized protein. (1035 aa)
	LOC100186426	Negative elongation factor B. (605 aa)
	F6SKY6_CIOIN	HDAg domain-containing protein. (537 aa)
	LOC100182171	Negative elongation factor E-like. (308 aa)
	F6SAD5_CIOIN	Uncharacterized protein; Belongs to the cyclin family. (514 aa)
	H2Y3S7_CIOIN	Uncharacterized protein. (633 aa)
	H2Y2L8_CIOIN	PWWP domain-containing protein. (161 aa)
	H2XXZ3_CIOIN	Uncharacterized protein. (870 aa)
	LOC100187353	Uncharacterized protein. (243 aa)
	H2XUU5_CIOIN	Uncharacterized protein. (532 aa)
	H2XNY4_CIOIN	EAF domain-containing protein. (241 aa)
	spt4	Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family. (122 aa)
	zf(ring)-23	RING-type domain-containing protein. (319 aa)
	F6XB76_CIOIN	SPT6_acidic domain-containing protein. (206 aa)
	LOC100177537	Protein kinase domain-containing protein. (1105 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6SAD5_CIOIN	F6SJ61_CIOIN	ENSCINP00000014389	ENSCINP00000015760	Uncharacterized protein; Belongs to the cyclin family.	HTH_44 domain-containing protein.	0.637
F6SAD5_CIOIN	F6SJH8_CIOIN	ENSCINP00000014389	ENSCINP00000015757	Uncharacterized protein; Belongs to the cyclin family.	S1 motif domain-containing protein.	0.637
F6SAD5_CIOIN	F6SKY6_CIOIN	ENSCINP00000014389	ENSCINP00000010608	Uncharacterized protein; Belongs to the cyclin family.	HDAg domain-containing protein.	0.813
F6SAD5_CIOIN	F6X618_CIOIN	ENSCINP00000014389	ENSCINP00000003619	Uncharacterized protein; Belongs to the cyclin family.	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	0.686
F6SAD5_CIOIN	F6XB76_CIOIN	ENSCINP00000014389	ENSCINP00000025852	Uncharacterized protein; Belongs to the cyclin family.	SPT6_acidic domain-containing protein.	0.637
F6SAD5_CIOIN	H2XNY4_CIOIN	ENSCINP00000014389	ENSCINP00000031367	Uncharacterized protein; Belongs to the cyclin family.	EAF domain-containing protein.	0.833
F6SAD5_CIOIN	H2XUU5_CIOIN	ENSCINP00000014389	ENSCINP00000033429	Uncharacterized protein; Belongs to the cyclin family.	Uncharacterized protein.	0.795
F6SAD5_CIOIN	H2Y3S7_CIOIN	ENSCINP00000014389	ENSCINP00000036562	Uncharacterized protein; Belongs to the cyclin family.	Uncharacterized protein.	0.924
F6SAD5_CIOIN	LOC100177537	ENSCINP00000014389	ENSCINP00000024069	Uncharacterized protein; Belongs to the cyclin family.	Protein kinase domain-containing protein.	0.999
F6SAD5_CIOIN	LOC100182171	ENSCINP00000014389	ENSCINP00000011919	Uncharacterized protein; Belongs to the cyclin family.	Negative elongation factor E-like.	0.909
F6SAD5_CIOIN	LOC100183139	ENSCINP00000014389	ENSCINP00000006432	Uncharacterized protein; Belongs to the cyclin family.	Uncharacterized protein.	0.833
F6SAD5_CIOIN	LOC100183995	ENSCINP00000014389	ENSCINP00000002121	Uncharacterized protein; Belongs to the cyclin family.	Uncharacterized protein.	0.799
F6SAD5_CIOIN	LOC100186426	ENSCINP00000014389	ENSCINP00000008498	Uncharacterized protein; Belongs to the cyclin family.	Negative elongation factor B.	0.843
F6SAD5_CIOIN	LOC494392	ENSCINP00000014389	ENSCINP00000017068	Uncharacterized protein; Belongs to the cyclin family.	Uncharacterized protein LOC494392.	0.716
F6SAD5_CIOIN	spt4	ENSCINP00000014389	ENSCINP00000029943	Uncharacterized protein; Belongs to the cyclin family.	Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family.	0.921
F6SJ61_CIOIN	F6SAD5_CIOIN	ENSCINP00000015760	ENSCINP00000014389	HTH_44 domain-containing protein.	Uncharacterized protein; Belongs to the cyclin family.	0.637
F6SJ61_CIOIN	F6SJH8_CIOIN	ENSCINP00000015760	ENSCINP00000015757	HTH_44 domain-containing protein.	S1 motif domain-containing protein.	0.969
F6SJ61_CIOIN	F6SKY6_CIOIN	ENSCINP00000015760	ENSCINP00000010608	HTH_44 domain-containing protein.	HDAg domain-containing protein.	0.540
F6SJ61_CIOIN	F6XB76_CIOIN	ENSCINP00000015760	ENSCINP00000025852	HTH_44 domain-containing protein.	SPT6_acidic domain-containing protein.	0.540
F6SJ61_CIOIN	H2XNY4_CIOIN	ENSCINP00000015760	ENSCINP00000031367	HTH_44 domain-containing protein.	EAF domain-containing protein.	0.744