(8 nodes) De novo NAD biosynthetic process from tryptophan network (Ciona intestinalis)

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Your Input:
	F6Z8U5_CIOIN	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. (281 aa)
	KYNU-2	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (467 aa)
	H2XQ19_CIOIN	Aminotran_5 domain-containing protein. (346 aa)
	H2XTJ5_CIOIN	FAD_binding_3 domain-containing protein. (252 aa)
	H2XW53_CIOIN	Uncharacterized protein. (138 aa)
	LOC100186313	Aminotran_5 domain-containing protein. (255 aa)
	KYNU-3	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (452 aa)
	KYNU	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (451 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6Z8U5_CIOIN	H2XQ19_CIOIN	ENSCINP00000023135	ENSCINP00000031753	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	Aminotran_5 domain-containing protein.	0.968
F6Z8U5_CIOIN	H2XTJ5_CIOIN	ENSCINP00000023135	ENSCINP00000032979	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	FAD_binding_3 domain-containing protein.	0.876
F6Z8U5_CIOIN	H2XW53_CIOIN	ENSCINP00000023135	ENSCINP00000033887	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	Uncharacterized protein.	0.548
F6Z8U5_CIOIN	KYNU	ENSCINP00000023135	ENSCINP00000015824	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	0.969
F6Z8U5_CIOIN	KYNU-2	ENSCINP00000023135	ENSCINP00000031473	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	0.969
F6Z8U5_CIOIN	KYNU-3	ENSCINP00000023135	ENSCINP00000034805	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	0.968
F6Z8U5_CIOIN	LOC100186313	ENSCINP00000023135	ENSCINP00000034361	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	Aminotran_5 domain-containing protein.	0.968
H2XQ19_CIOIN	F6Z8U5_CIOIN	ENSCINP00000031753	ENSCINP00000023135	Aminotran_5 domain-containing protein.	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	0.968
H2XQ19_CIOIN	H2XTJ5_CIOIN	ENSCINP00000031753	ENSCINP00000032979	Aminotran_5 domain-containing protein.	FAD_binding_3 domain-containing protein.	0.979
H2XQ19_CIOIN	H2XW53_CIOIN	ENSCINP00000031753	ENSCINP00000033887	Aminotran_5 domain-containing protein.	Uncharacterized protein.	0.502
H2XTJ5_CIOIN	F6Z8U5_CIOIN	ENSCINP00000032979	ENSCINP00000023135	FAD_binding_3 domain-containing protein.	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	0.876
H2XTJ5_CIOIN	H2XQ19_CIOIN	ENSCINP00000032979	ENSCINP00000031753	FAD_binding_3 domain-containing protein.	Aminotran_5 domain-containing protein.	0.979
H2XTJ5_CIOIN	H2XW53_CIOIN	ENSCINP00000032979	ENSCINP00000033887	FAD_binding_3 domain-containing protein.	Uncharacterized protein.	0.735
H2XTJ5_CIOIN	KYNU	ENSCINP00000032979	ENSCINP00000015824	FAD_binding_3 domain-containing protein.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	0.979
H2XTJ5_CIOIN	KYNU-2	ENSCINP00000032979	ENSCINP00000031473	FAD_binding_3 domain-containing protein.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	0.979
H2XTJ5_CIOIN	KYNU-3	ENSCINP00000032979	ENSCINP00000034805	FAD_binding_3 domain-containing protein.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	0.978
H2XTJ5_CIOIN	LOC100186313	ENSCINP00000032979	ENSCINP00000034361	FAD_binding_3 domain-containing protein.	Aminotran_5 domain-containing protein.	0.979
H2XW53_CIOIN	F6Z8U5_CIOIN	ENSCINP00000033887	ENSCINP00000023135	Uncharacterized protein.	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	0.548
H2XW53_CIOIN	H2XQ19_CIOIN	ENSCINP00000033887	ENSCINP00000031753	Uncharacterized protein.	Aminotran_5 domain-containing protein.	0.502
H2XW53_CIOIN	H2XTJ5_CIOIN	ENSCINP00000033887	ENSCINP00000032979	Uncharacterized protein.	FAD_binding_3 domain-containing protein.	0.735