(34 nodes) Appendage morphogenesis network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	F6YVN3_CIOIN	Uncharacterized protein. (165 aa)
	F6XWC8_CIOIN	Uncharacterized protein. (3955 aa)
	F6ZYR4_CIOIN	Nipped-B protein. (723 aa)
	F6PL57_CIOIN	Uncharacterized protein. (1087 aa)
	Zf(c2h2)-18	Uncharacterized protein. (884 aa)
	F6WLW9_CIOIN	Uncharacterized protein. (1384 aa)
	sfrp2	Secreted frizzled-related protein isoform X1. (293 aa)
	smad4	Mothers against decapentaplegic homolog. (527 aa)
	notrlc	BHLH domain-containing protein. (297 aa)
	LOC100183624	Uncharacterized protein. (1303 aa)
	LOC100180339	Transmembrane protein 107-like isoform X1. (139 aa)
	F6X0V6_CIOIN	Uncharacterized protein. (426 aa)
	tbx2/3	T-box containing transcription factor isoform X2. (803 aa)
	F6R7B5_CIOIN	C2 domain-containing protein. (1218 aa)
	F6YM26_CIOIN	Uncharacterized protein. (155 aa)
	F7A6H8_CIOIN	Uncharacterized protein. (250 aa)
	F6U8H5_CIOIN	Uncharacterized protein. (1490 aa)
	F6V8F4_CIOIN	Uncharacterized protein. (215 aa)
	F6TER2_CIOIN	Protein kinase domain-containing protein. (206 aa)
	F6VRW9_CIOIN	Uncharacterized protein. (905 aa)
	F6RDQ7_CIOIN	Uncharacterized protein. (591 aa)
	LOC100178124	Inositol monophosphatase 3-like. (324 aa)
	LOC100182633	Peptidylprolyl isomerase. (215 aa)
	LOC100175237-2	Uncharacterized protein LOC100175237 isoform X1. (301 aa)
	H2XJT4_CIOIN	PHD-type domain-containing protein. (508 aa)
	LOC100179250	Nostrin. (569 aa)
	H2XQA4_CIOIN	Uncharacterized protein. (301 aa)
	H2XR26_CIOIN	Uncharacterized protein. (102 aa)
	H2XTQ6_CIOIN	SPOC domain-containing protein. (247 aa)
	H2XW97_CIOIN	Uncharacterized protein. (218 aa)
	H2XWS6_CIOIN	Calx-beta domain-containing protein. (220 aa)
	H2XZD3_CIOIN	Uncharacterized protein. (221 aa)
	H2Y0R6_CIOIN	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (227 aa)
	H2Y2G5_CIOIN	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (160 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6R7B5_CIOIN	F6RDQ7_CIOIN	ENSCINP00000018342	ENSCINP00000025479	C2 domain-containing protein.	Uncharacterized protein.	0.528
F6R7B5_CIOIN	F6WLW9_CIOIN	ENSCINP00000018342	ENSCINP00000010279	C2 domain-containing protein.	Uncharacterized protein.	0.495
F6RDQ7_CIOIN	F6R7B5_CIOIN	ENSCINP00000025479	ENSCINP00000018342	Uncharacterized protein.	C2 domain-containing protein.	0.528
F6RDQ7_CIOIN	LOC100180339	ENSCINP00000025479	ENSCINP00000015077	Uncharacterized protein.	Transmembrane protein 107-like isoform X1.	0.651
F6U8H5_CIOIN	F6WLW9_CIOIN	ENSCINP00000019435	ENSCINP00000010279	Uncharacterized protein.	Uncharacterized protein.	0.998
F6U8H5_CIOIN	F6X0V6_CIOIN	ENSCINP00000019435	ENSCINP00000017470	Uncharacterized protein.	Uncharacterized protein.	0.897
F6V8F4_CIOIN	F6YM26_CIOIN	ENSCINP00000022816	ENSCINP00000018681	Uncharacterized protein.	Uncharacterized protein.	0.456
F6V8F4_CIOIN	LOC100183624	ENSCINP00000022816	ENSCINP00000014439	Uncharacterized protein.	Uncharacterized protein.	0.519
F6WLW9_CIOIN	F6R7B5_CIOIN	ENSCINP00000010279	ENSCINP00000018342	Uncharacterized protein.	C2 domain-containing protein.	0.495
F6WLW9_CIOIN	F6U8H5_CIOIN	ENSCINP00000010279	ENSCINP00000019435	Uncharacterized protein.	Uncharacterized protein.	0.998
F6WLW9_CIOIN	F6X0V6_CIOIN	ENSCINP00000010279	ENSCINP00000017470	Uncharacterized protein.	Uncharacterized protein.	0.888
F6X0V6_CIOIN	F6U8H5_CIOIN	ENSCINP00000017470	ENSCINP00000019435	Uncharacterized protein.	Uncharacterized protein.	0.897
F6X0V6_CIOIN	F6WLW9_CIOIN	ENSCINP00000017470	ENSCINP00000010279	Uncharacterized protein.	Uncharacterized protein.	0.888
F6XWC8_CIOIN	H2XW97_CIOIN	ENSCINP00000003385	ENSCINP00000033931	Uncharacterized protein.	Uncharacterized protein.	0.418
F6XWC8_CIOIN	H2XWS6_CIOIN	ENSCINP00000003385	ENSCINP00000034110	Uncharacterized protein.	Calx-beta domain-containing protein.	0.412
F6YM26_CIOIN	F6V8F4_CIOIN	ENSCINP00000018681	ENSCINP00000022816	Uncharacterized protein.	Uncharacterized protein.	0.456
F6YM26_CIOIN	LOC100183624	ENSCINP00000018681	ENSCINP00000014439	Uncharacterized protein.	Uncharacterized protein.	0.519
F6ZYR4_CIOIN	H2XR26_CIOIN	ENSCINP00000005688	ENSCINP00000032110	Nipped-B protein.	Uncharacterized protein.	0.406
F6ZYR4_CIOIN	H2XZD3_CIOIN	ENSCINP00000005688	ENSCINP00000035017	Nipped-B protein.	Uncharacterized protein.	0.968
H2XQA4_CIOIN	H2XW97_CIOIN	ENSCINP00000031838	ENSCINP00000033931	Uncharacterized protein.	Uncharacterized protein.	0.950