(37 nodes) Tube formation network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	F6WBK6_CIOIN	TPR_REGION domain-containing protein. (446 aa)
	dsh	Dishevelled homolog. (685 aa)
	F6TF50_CIOIN	Uncharacterized protein. (1310 aa)
	F6VUF1_CIOIN	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (608 aa)
	F6V3W8_CIOIN	Uncharacterized protein. (264 aa)
	F6RDQ7_CIOIN	Uncharacterized protein. (591 aa)
	F6UMR8_CIOIN	Uncharacterized protein. (477 aa)
	F6UMH0_CIOIN	WW domain-containing protein. (284 aa)
	LOC100184081	Uncharacterized protein. (305 aa)
	H2XJG1_CIOIN	RING-type domain-containing protein. (147 aa)
	H2XKE2_CIOIN	Uncharacterized protein. (2486 aa)
	Q1RPY5_CIOIN	Zinc finger protein. (579 aa)
	H2XP71_CIOIN	Bromo domain-containing protein. (495 aa)
	H2XRJ3_CIOIN	Protein kinase domain-containing protein. (195 aa)
	H2XUQ8_CIOIN	Uncharacterized protein. (225 aa)
	LOC100185063	ectodysplasin-A; Belongs to the tumor necrosis factor family. (371 aa)
	H2XWZ5_CIOIN	Uncharacterized protein. (346 aa)
	H2XYC7_CIOIN	Uncharacterized protein. (197 aa)
	F6Z4V3_CIOIN	Tyrosine-protein kinase. (440 aa)
	F7BAA5_CIOIN	Uncharacterized protein. (261 aa)
	LOC100187265	Uncharacterized protein. (949 aa)
	F7B997_CIOIN	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (759 aa)
	sfrp2	Secreted frizzled-related protein isoform X1. (293 aa)
	LOC100180174	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (650 aa)
	LOC100176009	cAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (367 aa)
	Ci-ZF(ZZ)-7	Zinc finger protein. (619 aa)
	F7A8B4_CIOIN	Uncharacterized protein. (495 aa)
	F7A801_CIOIN	Uncharacterized protein. (389 aa)
	F6ZAD3_CIOIN	Rap-GAP domain-containing protein. (1434 aa)
	deaf-1	Deformed epidermal autoregulatory factor 1 homolog isoform X2. (561 aa)
	LOC100185086	Uncharacterized protein. (126 aa)
	F7A2I6_CIOIN	Uncharacterized protein. (311 aa)
	F6Z6K5_CIOIN	Suppressor of fused homolog. (473 aa)
	LOC100176668	Transmembrane emp24 domain-containing protein 2. (203 aa)
	F6X0V6_CIOIN	Uncharacterized protein. (426 aa)
	Ci-Net	Transcription factor protein. (205 aa)
	LOC100185664	C-1-tetrahydrofolate synthase, cytoplasmic-like. (934 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Ci-ZF(ZZ)-7	H2XJG1_CIOIN	ENSCINP00000001354	ENSCINP00000029793	Zinc finger protein.	RING-type domain-containing protein.	0.895
F6TF50_CIOIN	F6UMH0_CIOIN	ENSCINP00000023576	ENSCINP00000025950	Uncharacterized protein.	WW domain-containing protein.	0.734
F6TF50_CIOIN	F6UMR8_CIOIN	ENSCINP00000023576	ENSCINP00000025949	Uncharacterized protein.	Uncharacterized protein.	0.734
F6TF50_CIOIN	F6X0V6_CIOIN	ENSCINP00000023576	ENSCINP00000017470	Uncharacterized protein.	Uncharacterized protein.	0.455
F6TF50_CIOIN	LOC100184081	ENSCINP00000023576	ENSCINP00000027834	Uncharacterized protein.	Uncharacterized protein.	0.405
F6TF50_CIOIN	LOC100187265	ENSCINP00000023576	ENSCINP00000009399	Uncharacterized protein.	Uncharacterized protein.	0.685
F6UMH0_CIOIN	F6TF50_CIOIN	ENSCINP00000025950	ENSCINP00000023576	WW domain-containing protein.	Uncharacterized protein.	0.734
F6UMH0_CIOIN	F6UMR8_CIOIN	ENSCINP00000025950	ENSCINP00000025949	WW domain-containing protein.	Uncharacterized protein.	0.900
F6UMR8_CIOIN	F6TF50_CIOIN	ENSCINP00000025949	ENSCINP00000023576	Uncharacterized protein.	Uncharacterized protein.	0.734
F6UMR8_CIOIN	F6UMH0_CIOIN	ENSCINP00000025949	ENSCINP00000025950	Uncharacterized protein.	WW domain-containing protein.	0.900
F6VUF1_CIOIN	dsh	ENSCINP00000024011	ENSCINP00000019640	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Dishevelled homolog.	0.515
F6VUF1_CIOIN	sfrp2	ENSCINP00000024011	ENSCINP00000010646	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Secreted frizzled-related protein isoform X1.	0.960
F6WBK6_CIOIN	F6X0V6_CIOIN	ENSCINP00000019082	ENSCINP00000017470	TPR_REGION domain-containing protein.	Uncharacterized protein.	0.602
F6WBK6_CIOIN	LOC100184081	ENSCINP00000019082	ENSCINP00000027834	TPR_REGION domain-containing protein.	Uncharacterized protein.	0.488
F6X0V6_CIOIN	F6TF50_CIOIN	ENSCINP00000017470	ENSCINP00000023576	Uncharacterized protein.	Uncharacterized protein.	0.455
F6X0V6_CIOIN	F6WBK6_CIOIN	ENSCINP00000017470	ENSCINP00000019082	Uncharacterized protein.	TPR_REGION domain-containing protein.	0.602
F6X0V6_CIOIN	F6Z6K5_CIOIN	ENSCINP00000017470	ENSCINP00000016536	Uncharacterized protein.	Suppressor of fused homolog.	0.562
F6X0V6_CIOIN	LOC100184081	ENSCINP00000017470	ENSCINP00000027834	Uncharacterized protein.	Uncharacterized protein.	0.987
F6Z6K5_CIOIN	F6X0V6_CIOIN	ENSCINP00000016536	ENSCINP00000017470	Suppressor of fused homolog.	Uncharacterized protein.	0.562
F6Z6K5_CIOIN	LOC100176009	ENSCINP00000016536	ENSCINP00000013406	Suppressor of fused homolog.	cAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily.	0.765