STRINGSTRING
H2XKE2_CIOIN H2XKE2_CIOIN LOC100179250 LOC100179250 Q1RPY5_CIOIN Q1RPY5_CIOIN LOC100178517 LOC100178517 Bmp2/4 Bmp2/4 hox13 hox13 LOC100178688 LOC100178688 H2XP71_CIOIN H2XP71_CIOIN H2XQ88_CIOIN H2XQ88_CIOIN H2XR26_CIOIN H2XR26_CIOIN H2XRJ3_CIOIN H2XRJ3_CIOIN H2XRM3_CIOIN H2XRM3_CIOIN srf srf LOC100185578 LOC100185578 H2XTC3_CIOIN H2XTC3_CIOIN H2XTM7_CIOIN H2XTM7_CIOIN H2XTQ6_CIOIN H2XTQ6_CIOIN H2XUF2_CIOIN H2XUF2_CIOIN H2XUI8_CIOIN H2XUI8_CIOIN LOC100175445 LOC100175445 H2XUQ8_CIOIN H2XUQ8_CIOIN H2XWC7_CIOIN H2XWC7_CIOIN H2XWZ5_CIOIN H2XWZ5_CIOIN H2XX02_CIOIN H2XX02_CIOIN H2XXD3_CIOIN H2XXD3_CIOIN hlx hlx H2XYC7_CIOIN H2XYC7_CIOIN H2XYT4_CIOIN H2XYT4_CIOIN H2XZD3_CIOIN H2XZD3_CIOIN H2Y015_CIOIN H2Y015_CIOIN Vdr-b Vdr-b H2Y0K6_CIOIN H2Y0K6_CIOIN H2Y0R6_CIOIN H2Y0R6_CIOIN H2Y1D7_CIOIN H2Y1D7_CIOIN H2Y1F5_CIOIN H2Y1F5_CIOIN H2Y1V1_CIOIN H2Y1V1_CIOIN H2Y255_CIOIN H2Y255_CIOIN H2Y2G5_CIOIN H2Y2G5_CIOIN LOC100176205 LOC100176205 F6WUP4_CIOIN F6WUP4_CIOIN F6U6Y7_CIOIN F6U6Y7_CIOIN F6SLT5_CIOIN F6SLT5_CIOIN F6RYH5_CIOIN F6RYH5_CIOIN F7B6D7_CIOIN F7B6D7_CIOIN F6YH93_CIOIN F6YH93_CIOIN delta delta LOC100187265 LOC100187265 zf(c2h2)-46 zf(c2h2)-46 F6PLX9_CIOIN F6PLX9_CIOIN F7B997_CIOIN F7B997_CIOIN Xbpa Xbpa sfrp2 sfrp2 tbx20 tbx20 LOC100181891 LOC100181891 smad4 smad4 Ephrin-a Ephrin-a F6T5Q7_CIOIN F6T5Q7_CIOIN Tgfbr-iib Tgfbr-iib LOC100185063 LOC100185063 LOC100183377 LOC100183377 Ci-ZF(ZZ)-7 Ci-ZF(ZZ)-7 F6UPI8_CIOIN F6UPI8_CIOIN soxE soxE F6SYF4_CIOIN F6SYF4_CIOIN Smoothened Smoothened LOC100177697 LOC100177697 F6Z442_CIOIN F6Z442_CIOIN LOC100184368 LOC100184368 tgfbr-ia tgfbr-ia p53/p73-a p53/p73-a Hif Hif P53/p73-b P53/p73-b LOC100178927 LOC100178927 F6UFG8_CIOIN F6UFG8_CIOIN F6ZYR4_CIOIN F6ZYR4_CIOIN F6XN00_CIOIN F6XN00_CIOIN LOC100185664 LOC100185664 F6PHN1_CIOIN F6PHN1_CIOIN F6Z4V3_CIOIN F6Z4V3_CIOIN F6SPE4_CIOIN F6SPE4_CIOIN F7BAA5_CIOIN F7BAA5_CIOIN F6TLX0_CIOIN F6TLX0_CIOIN F6TLJ7_CIOIN F6TLJ7_CIOIN F6TLB6_CIOIN F6TLB6_CIOIN Hand Hand LOC100181537 LOC100181537 F6VUM2_CIOIN F6VUM2_CIOIN F6PSM8_CIOIN F6PSM8_CIOIN LOC100180174 LOC100180174 LOC100176009 LOC100176009 F6RJA6_CIOIN F6RJA6_CIOIN F6RI21_CIOIN F6RI21_CIOIN notrlc notrlc LOC100176761 LOC100176761 F7A8B4_CIOIN F7A8B4_CIOIN F7A801_CIOIN F7A801_CIOIN F6VEQ7_CIOIN F6VEQ7_CIOIN Cifrz Cifrz LOC100180112 LOC100180112 F6SYX7_CIOIN F6SYX7_CIOIN Foxh-a Foxh-a Cibeta-catenin Cibeta-catenin LOC100176171 LOC100176171 F6ZAD3_CIOIN F6ZAD3_CIOIN F6VZ12_CIOIN F6VZ12_CIOIN deaf-1 deaf-1 xbpd xbpd mox mox F6YIG5_CIOIN F6YIG5_CIOIN LOC100185086 LOC100185086 F7A2I6_CIOIN F7A2I6_CIOIN F7A2D4_CIOIN F7A2D4_CIOIN F6Z6K5_CIOIN F6Z6K5_CIOIN LOC100176668 LOC100176668 F6X0V6_CIOIN F6X0V6_CIOIN F6TQ49_CIOIN F6TQ49_CIOIN LOC100177133 LOC100177133 tbx2/3 tbx2/3 Ci-Net Ci-Net F6Q6M5_CIOIN F6Q6M5_CIOIN F6WNG6_CIOIN F6WNG6_CIOIN Fgf8/17/18 Fgf8/17/18 F6Z402_CIOIN F6Z402_CIOIN F6WXG6_CIOIN F6WXG6_CIOIN F6WBK6_CIOIN F6WBK6_CIOIN Collagen_XVIII Collagen_XVIII dsh dsh xbpb xbpb F6UXY9_CIOIN F6UXY9_CIOIN tgfbeta-na4 tgfbeta-na4 LOC100179157 LOC100179157 LOC100178138 LOC100178138 F6YJE0_CIOIN F6YJE0_CIOIN F6U5Q2_CIOIN F6U5Q2_CIOIN F6TF50_CIOIN F6TF50_CIOIN F6VUF1_CIOIN F6VUF1_CIOIN F6ZHF5_CIOIN F6ZHF5_CIOIN nk4 nk4 Xbpc Xbpc F6YXM6_CIOIN F6YXM6_CIOIN F6V3W8_CIOIN F6V3W8_CIOIN F6YVN3_CIOIN F6YVN3_CIOIN F6UBD0_CIOIN F6UBD0_CIOIN F6TNP4_CIOIN F6TNP4_CIOIN F6Q301_CIOIN F6Q301_CIOIN F6RDQ7_CIOIN F6RDQ7_CIOIN F6UMR8_CIOIN F6UMR8_CIOIN F6UMH0_CIOIN F6UMH0_CIOIN F6TZA7_CIOIN F6TZA7_CIOIN F6XM19_CIOIN F6XM19_CIOIN F6XLS2_CIOIN F6XLS2_CIOIN Klf2 Klf2 F6Y6R0_CIOIN F6Y6R0_CIOIN F6XYH1_CIOIN F6XYH1_CIOIN LOC100101826 LOC100101826 F6SLD6_CIOIN F6SLD6_CIOIN LOC100182633 LOC100182633 LOC778850 LOC778850 LOC100175237-2 LOC100175237-2 LOC100184081 LOC100184081 LOC779004 LOC779004 LOC778836 LOC778836 LOC100183546 LOC100183546 F6W3W9_CIOIN F6W3W9_CIOIN F6T2G1_CIOIN F6T2G1_CIOIN H2XJG1_CIOIN H2XJG1_CIOIN H2XK34_CIOIN H2XK34_CIOIN H2XKR8_CIOIN H2XKR8_CIOIN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
H2XKE2_CIOINUncharacterized protein. (2486 aa)
LOC100179250Nostrin. (569 aa)
Q1RPY5_CIOINZinc finger protein. (579 aa)
LOC100178517Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (142 aa)
Bmp2/4TGFb_propeptide domain-containing protein. (376 aa)
hox13Homeobox transcription factor Hox13. (152 aa)
LOC100178688Uncharacterized protein LOC100178688. (632 aa)
H2XP71_CIOINBromo domain-containing protein. (495 aa)
H2XQ88_CIOINFibrinogen C-terminal domain-containing protein. (331 aa)
H2XR26_CIOINUncharacterized protein. (102 aa)
H2XRJ3_CIOINProtein kinase domain-containing protein. (195 aa)
H2XRM3_CIOINUncharacterized protein. (212 aa)
srfTranscription factor protein. (335 aa)
LOC100185578Aminoacyl tRNA synthase complex-interacting multifunctional protein 1. (297 aa)
H2XTC3_CIOINFork-head domain-containing protein. (119 aa)
H2XTM7_CIOINRho-GAP domain-containing protein. (203 aa)
H2XTQ6_CIOINSPOC domain-containing protein. (247 aa)
H2XUF2_CIOINProtein kinase domain-containing protein. (202 aa)
H2XUI8_CIOINEGF-like domain-containing protein. (158 aa)
LOC100175445Uncharacterized protein. (864 aa)
H2XUQ8_CIOINUncharacterized protein. (225 aa)
H2XWC7_CIOINUncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (170 aa)
H2XWZ5_CIOINUncharacterized protein. (346 aa)
H2XX02_CIOINIg-like domain-containing protein. (221 aa)
H2XXD3_CIOINUncharacterized protein; Belongs to the protein kinase superfamily. (314 aa)
hlxHomeobox domain-containing protein. (554 aa)
H2XYC7_CIOINUncharacterized protein. (197 aa)
H2XYT4_CIOINUncharacterized protein. (423 aa)
H2XZD3_CIOINUncharacterized protein. (221 aa)
H2Y015_CIOINEGF-like domain-containing protein. (182 aa)
Vdr-bNR LBD domain-containing protein. (128 aa)
H2Y0K6_CIOINUncharacterized protein. (3252 aa)
H2Y0R6_CIOINMediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (227 aa)
H2Y1D7_CIOINNAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX; Belongs to the NnrE/AIBP family. (281 aa)
H2Y1F5_CIOINFibrinogen C-terminal domain-containing protein. (283 aa)
H2Y1V1_CIOINPH domain-containing protein. (179 aa)
H2Y255_CIOINCTCK domain-containing protein. (191 aa)
H2Y2G5_CIOINMediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (160 aa)
LOC100176205Programmed cell death protein 10. (217 aa)
F6WUP4_CIOINUncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1014 aa)
F6U6Y7_CIOINUncharacterized protein. (421 aa)
F6SLT5_CIOINAminopeptidase. (888 aa)
F6RYH5_CIOINUncharacterized protein. (814 aa)
F7B6D7_CIOINCOMM domain-containing protein. (224 aa)
F6YH93_CIOINUncharacterized protein. (1111 aa)
deltaDelta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (706 aa)
LOC100187265Uncharacterized protein. (949 aa)
zf(c2h2)-46Zinc finger protein (C2H2)-46. (600 aa)
F6PLX9_CIOINUncharacterized protein. (389 aa)
F7B997_CIOINDynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (759 aa)
XbpaBZIP domain-containing protein. (309 aa)
sfrp2Secreted frizzled-related protein isoform X1. (293 aa)
tbx20Uncharacterized protein. (437 aa)
LOC100181891Uncharacterized protein. (373 aa)
smad4Mothers against decapentaplegic homolog. (527 aa)
Ephrin-aEphrin RBD domain-containing protein; Belongs to the ephrin family. (248 aa)
F6T5Q7_CIOINUncharacterized protein. (481 aa)
Tgfbr-iibReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (567 aa)
LOC100185063ectodysplasin-A; Belongs to the tumor necrosis factor family. (371 aa)
LOC100183377Vasohibin-1-like isoform X2. (319 aa)
Ci-ZF(ZZ)-7Zinc finger protein. (619 aa)
F6UPI8_CIOINFork-head domain-containing protein. (596 aa)
soxESoxE protein. (808 aa)
F6SYF4_CIOINUncharacterized protein. (572 aa)
SmoothenedUncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (441 aa)
LOC100177697Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (236 aa)
F6Z442_CIOINFibrinogen C-terminal domain-containing protein. (331 aa)
LOC100184368Integrin-linked protein kinase. (447 aa)
tgfbr-iaReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (423 aa)
p53/p73-aTranscription factor protein. (489 aa)
HifPAS domain-containing protein. (531 aa)
P53/p73-bUncharacterized protein. (419 aa)
LOC100178927Uncharacterized protein LOC100178927. (323 aa)
F6UFG8_CIOINUncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (136 aa)
F6ZYR4_CIOINNipped-B protein. (723 aa)
F6XN00_CIOINProtein kinase domain-containing protein. (251 aa)
LOC100185664C-1-tetrahydrofolate synthase, cytoplasmic-like. (934 aa)
F6PHN1_CIOINProtein kinase domain-containing protein. (1026 aa)
F6Z4V3_CIOINTyrosine-protein kinase. (440 aa)
F6SPE4_CIOINUncharacterized protein. (185 aa)
F7BAA5_CIOINUncharacterized protein. (261 aa)
F6TLX0_CIOINUncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (817 aa)
F6TLJ7_CIOINUncharacterized protein. (895 aa)
F6TLB6_CIOINUncharacterized protein. (891 aa)
HandBHLH domain-containing protein. (378 aa)
LOC100181537Junctional adhesion molecule C-like isoform X1. (327 aa)
F6VUM2_CIOINGlutamine synthetase. (334 aa)
F6PSM8_CIOINUncharacterized protein. (690 aa)
LOC100180174Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (650 aa)
LOC100176009cAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (367 aa)
F6RJA6_CIOINUncharacterized protein. (322 aa)
F6RI21_CIOINUncharacterized protein. (355 aa)
notrlcBHLH domain-containing protein. (297 aa)
LOC100176761WD_REPEATS_REGION domain-containing protein. (383 aa)
F7A8B4_CIOINUncharacterized protein. (495 aa)
F7A801_CIOINUncharacterized protein. (389 aa)
F6VEQ7_CIOINRFX-type winged-helix domain-containing protein. (624 aa)
CifrzUncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (866 aa)
LOC100180112Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1106 aa)
F6SYX7_CIOINUncharacterized protein. (624 aa)
Foxh-aFork-head domain-containing protein. (455 aa)
Cibeta-cateninUncharacterized protein. (497 aa)
LOC100176171Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6-A. (389 aa)
F6ZAD3_CIOINRap-GAP domain-containing protein. (1434 aa)
F6VZ12_CIOINUncharacterized protein. (641 aa)
deaf-1Deformed epidermal autoregulatory factor 1 homolog isoform X2. (561 aa)
xbpdTranscription factor protein isoform X1. (366 aa)
moxTranscription factor protein. (176 aa)
F6YIG5_CIOINTetraspanin. (261 aa)
LOC100185086Uncharacterized protein. (126 aa)
F7A2I6_CIOINUncharacterized protein. (311 aa)
F7A2D4_CIOINBPTI/Kunitz inhibitor domain-containing protein. (271 aa)
F6Z6K5_CIOINSuppressor of fused homolog. (473 aa)
LOC100176668Transmembrane emp24 domain-containing protein 2. (203 aa)
F6X0V6_CIOINUncharacterized protein. (426 aa)
F6TQ49_CIOINANK_REP_REGION domain-containing protein. (147 aa)
LOC100177133ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (520 aa)
tbx2/3T-box containing transcription factor isoform X2. (803 aa)
Ci-NetTranscription factor protein. (205 aa)
F6Q6M5_CIOINUncharacterized protein. (339 aa)
F6WNG6_CIOINCUB domain-containing protein. (527 aa)
Fgf8/17/18Uncharacterized protein; Belongs to the heparin-binding growth factors family. (414 aa)
F6Z402_CIOINPeptidase S72 domain-containing protein. (410 aa)
F6WXG6_CIOINUncharacterized protein; Belongs to the peptidase C1 family. (333 aa)
F6WBK6_CIOINTPR_REGION domain-containing protein. (446 aa)
Collagen_XVIIIEndostatin domain-containing protein. (950 aa)
dshDishevelled homolog. (685 aa)
xbpbTranscription factor protein. (238 aa)
F6UXY9_CIOINARID domain-containing protein. (428 aa)
tgfbeta-na4TGF_BETA_2 domain-containing protein. (442 aa)
LOC100179157Coiled-coil domain-containing protein 134. (223 aa)
LOC100178138Hedgehog-interacting protein-like. (240 aa)
F6YJE0_CIOINUncharacterized protein. (772 aa)
F6U5Q2_CIOINUncharacterized protein. (203 aa)
F6TF50_CIOINUncharacterized protein. (1310 aa)
F6VUF1_CIOINProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (608 aa)
F6ZHF5_CIOINProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (369 aa)
nk4Transcription factor protein. (623 aa)
XbpcBZIP domain-containing protein. (437 aa)
F6YXM6_CIOINProtein kinase domain-containing protein. (722 aa)
F6V3W8_CIOINUncharacterized protein. (264 aa)
F6YVN3_CIOINUncharacterized protein. (165 aa)
F6UBD0_CIOINUncharacterized protein. (191 aa)
F6TNP4_CIOINUncharacterized protein. (2097 aa)
F6Q301_CIOINUncharacterized protein. (237 aa)
F6RDQ7_CIOINUncharacterized protein. (591 aa)
F6UMR8_CIOINUncharacterized protein. (477 aa)
F6UMH0_CIOINWW domain-containing protein. (284 aa)
F6TZA7_CIOINUncharacterized protein. (273 aa)
F6XM19_CIOINUncharacterized protein. (446 aa)
F6XLS2_CIOINUncharacterized protein. (745 aa)
Klf2Uncharacterized protein. (610 aa)
F6Y6R0_CIOINUncharacterized protein. (393 aa)
F6XYH1_CIOINUncharacterized protein. (418 aa)
LOC100101826Uncharacterized protein. (894 aa)
F6SLD6_CIOINDeacetylase sirtuin-type domain-containing protein. (737 aa)
LOC100182633Peptidylprolyl isomerase. (215 aa)
LOC778850Zinc finger protein. (676 aa)
LOC100175237-2Uncharacterized protein LOC100175237 isoform X1. (301 aa)
LOC100184081Uncharacterized protein. (305 aa)
LOC779004Transcription factor protein. (553 aa)
LOC778836Homeobox domain-containing protein. (146 aa)
LOC100183546Dynein assembly factor 1, axonemal homolog. (628 aa)
F6W3W9_CIOINUncharacterized protein. (758 aa)
F6T2G1_CIOINUncharacterized protein. (298 aa)
H2XJG1_CIOINRING-type domain-containing protein. (147 aa)
H2XK34_CIOINUncharacterized protein. (286 aa)
H2XKR8_CIOINUncharacterized protein. (137 aa)
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
Server load: low (34%) [HD]