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H2XUY6_CIOIN | Cullin_Nedd8 domain-containing protein; Belongs to the cullin family. (145 aa) | ||||
F6R472_CIOIN | CULLIN_2 domain-containing protein; Belongs to the cullin family. (707 aa) | ||||
H2XXU4_CIOIN | Uncharacterized protein. (275 aa) | ||||
F6RCY1_CIOIN | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (504 aa) |