(39 nodes) Regulation of gene expression, epigenetic network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Zf(cxxc)-5	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1257 aa)
	F6YT81_CIOIN	Uncharacterized protein. (157 aa)
	F6WNH2_CIOIN	Ribosomal RNA-processing protein 8; Probable methyltransferase required to silence rDNA. Belongs to the methyltransferase superfamily. RRP8 family. (315 aa)
	LOC100182930	Centromere protein V-like. (142 aa)
	F6R4R6_CIOIN	HRDC domain-containing protein. (292 aa)
	gsk	Glycogen synthase kinase Alpha/beta. (407 aa)
	LOC100180444	BAH domain-containing protein. (230 aa)
	LOC100176656	lamin-L(II)-like isoform X1; Belongs to the intermediate filament family. (465 aa)
	Sir2-d	Deacetylase sirtuin-type domain-containing protein. (91 aa)
	F6W7J0_CIOIN	Uncharacterized protein. (224 aa)
	F6YKS6_CIOIN	Uncharacterized protein. (1773 aa)
	H2XJH1_CIOIN	Uncharacterized protein. (764 aa)
	F6VQG0_CIOIN	Uncharacterized protein. (160 aa)
	F6SLD6_CIOIN	Deacetylase sirtuin-type domain-containing protein. (737 aa)
	F7BGB4_CIOIN	Uncharacterized protein. (97 aa)
	tcfl1	Ci-TCFL1 protein. (333 aa)
	H2Y1X7_CIOIN	Uncharacterized protein. (191 aa)
	H2Y156_CIOIN	Uncharacterized protein. (200 aa)
	H2XYT6_CIOIN	3'-5' exonuclease domain-containing protein. (261 aa)
	H2XXT8_CIOIN	Uncharacterized protein. (189 aa)
	H2XU97_CIOIN	HRDC domain-containing protein. (194 aa)
	cbf-2	Transcription factor CBF/NF-Y/archaeal histone -2. (156 aa)
	H2XQ41_CIOIN	UDG domain-containing protein. (250 aa)
	zf(c2h2)-30	Uncharacterized protein. (520 aa)
	H2XLZ0_CIOIN	RING-type domain-containing protein. (223 aa)
	H2XK62_CIOIN	Histone-lysine N-methyltransferase, H3 lysine-79 specific. (256 aa)
	F6SQW7_CIOIN	Uncharacterized protein. (328 aa)
	F6YXL4_CIOIN	AAA_12 domain-containing protein. (78 aa)
	Rbp1-like	ARID domain-containing protein. (1195 aa)
	F6ZU29_CIOIN	Uncharacterized protein. (188 aa)
	F6QH43_CIOIN	RING-type domain-containing protein. (309 aa)
	F6WQW9_CIOIN	Uncharacterized protein. (301 aa)
	F6Z8G0_CIOIN	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (454 aa)
	LOC100183669	Protein phosphatase 1D isoform X1. (515 aa)
	F6Y7R5_CIOIN	Amine oxidase. (802 aa)
	LOC100184517	Histone acetyltransferase type B catalytic subunit. (408 aa)
	F6ZFK4_CIOIN	Uncharacterized protein. (809 aa)
	kcnq1	Uncharacterized protein; Belongs to the potassium channel family. (520 aa)
	F6UIA2_CIOIN	Protein arginine N-methyltransferase; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA). (696 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6QH43_CIOIN	F6WQW9_CIOIN	ENSCINP00000020173	ENSCINP00000016333	RING-type domain-containing protein.	Uncharacterized protein.	0.423
F6QH43_CIOIN	F6Z8G0_CIOIN	ENSCINP00000020173	ENSCINP00000016265	RING-type domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.805
F6QH43_CIOIN	H2XLZ0_CIOIN	ENSCINP00000020173	ENSCINP00000030672	RING-type domain-containing protein.	RING-type domain-containing protein.	0.551
F6R4R6_CIOIN	H2XU97_CIOIN	ENSCINP00000004852	ENSCINP00000033231	HRDC domain-containing protein.	HRDC domain-containing protein.	0.554
F6R4R6_CIOIN	H2XYT6_CIOIN	ENSCINP00000004852	ENSCINP00000034820	HRDC domain-containing protein.	3'-5' exonuclease domain-containing protein.	0.904
F6SLD6_CIOIN	F6WNH2_CIOIN	ENSCINP00000027486	ENSCINP00000006739	Deacetylase sirtuin-type domain-containing protein.	Ribosomal RNA-processing protein 8; Probable methyltransferase required to silence rDNA. Belongs to the methyltransferase superfamily. RRP8 family.	0.819
F6SLD6_CIOIN	F6WQW9_CIOIN	ENSCINP00000027486	ENSCINP00000016333	Deacetylase sirtuin-type domain-containing protein.	Uncharacterized protein.	0.574
F6SLD6_CIOIN	H2XK62_CIOIN	ENSCINP00000027486	ENSCINP00000030044	Deacetylase sirtuin-type domain-containing protein.	Histone-lysine N-methyltransferase, H3 lysine-79 specific.	0.654
F6SLD6_CIOIN	Sir2-d	ENSCINP00000027486	ENSCINP00000002463	Deacetylase sirtuin-type domain-containing protein.	Deacetylase sirtuin-type domain-containing protein.	0.590
F6SLD6_CIOIN	Zf(cxxc)-5	ENSCINP00000027486	ENSCINP00000010797	Deacetylase sirtuin-type domain-containing protein.	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	0.495
F6W7J0_CIOIN	F6YT81_CIOIN	ENSCINP00000002812	ENSCINP00000007327	Uncharacterized protein.	Uncharacterized protein.	0.926
F6WNH2_CIOIN	F6SLD6_CIOIN	ENSCINP00000006739	ENSCINP00000027486	Ribosomal RNA-processing protein 8; Probable methyltransferase required to silence rDNA. Belongs to the methyltransferase superfamily. RRP8 family.	Deacetylase sirtuin-type domain-containing protein.	0.819
F6WNH2_CIOIN	LOC100180444	ENSCINP00000006739	ENSCINP00000001353	Ribosomal RNA-processing protein 8; Probable methyltransferase required to silence rDNA. Belongs to the methyltransferase superfamily. RRP8 family.	BAH domain-containing protein.	0.540
F6WNH2_CIOIN	Sir2-d	ENSCINP00000006739	ENSCINP00000002463	Ribosomal RNA-processing protein 8; Probable methyltransferase required to silence rDNA. Belongs to the methyltransferase superfamily. RRP8 family.	Deacetylase sirtuin-type domain-containing protein.	0.400
F6WQW9_CIOIN	F6QH43_CIOIN	ENSCINP00000016333	ENSCINP00000020173	Uncharacterized protein.	RING-type domain-containing protein.	0.423
F6WQW9_CIOIN	F6SLD6_CIOIN	ENSCINP00000016333	ENSCINP00000027486	Uncharacterized protein.	Deacetylase sirtuin-type domain-containing protein.	0.574
F6WQW9_CIOIN	F6ZFK4_CIOIN	ENSCINP00000016333	ENSCINP00000012556	Uncharacterized protein.	Uncharacterized protein.	0.478
F6WQW9_CIOIN	H2XJH1_CIOIN	ENSCINP00000016333	ENSCINP00000029803	Uncharacterized protein.	Uncharacterized protein.	0.478
F6WQW9_CIOIN	H2XK62_CIOIN	ENSCINP00000016333	ENSCINP00000030044	Uncharacterized protein.	Histone-lysine N-methyltransferase, H3 lysine-79 specific.	0.479
F6WQW9_CIOIN	H2XLZ0_CIOIN	ENSCINP00000016333	ENSCINP00000030672	Uncharacterized protein.	RING-type domain-containing protein.	0.795