(41 nodes) Glucose homeostasis network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	F7AZD3_CIOIN	Glucose-6-phosphate isomerase; Belongs to the GPI family. (232 aa)
	F6YCG7_CIOIN	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1086 aa)
	Ipf1	Homeobox domain-containing protein. (411 aa)
	Sir2-d	Deacetylase sirtuin-type domain-containing protein. (91 aa)
	Rev-erb	Uncharacterized protein. (597 aa)
	LOC100184788	Non-specific serine/threonine protein kinase. (554 aa)
	F6U899_CIOIN	DJ-1_PfpI domain-containing protein. (187 aa)
	Ci-FXR	Nuclear receptor. (294 aa)
	F6XH38_CIOIN	Uncharacterized protein. (637 aa)
	Zf(c2h2)-5	Uncharacterized protein. (513 aa)
	Xbpa	BZIP domain-containing protein. (309 aa)
	F6ZGZ0_CIOIN	Uncharacterized protein. (615 aa)
	F6ZGX7_CIOIN	Uncharacterized protein. (629 aa)
	LOC100177066	Uncharacterized protein. (641 aa)
	foxk	Uncharacterized protein. (614 aa)
	F6RS66_CIOIN	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (462 aa)
	F6YLI3_CIOIN	Phosphotransferase. (482 aa)
	xbpd	Transcription factor protein isoform X1. (366 aa)
	LOC100185148	Volume-regulated anion channel subunit LRRC8B. (480 aa)
	zf(c2h2)-38	Zinc finger protein 38. (1067 aa)
	F6XRP8_CIOIN	MFS domain-containing protein. (445 aa)
	Mist	BHLH domain-containing protein. (550 aa)
	LOC100186815	Insulin-like growth factor-binding protein 5. (225 aa)
	F6Y4X1_CIOIN	Na_Ca_ex domain-containing protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (351 aa)
	F6R022_CIOIN	Uncharacterized protein. (309 aa)
	F6Z326_CIOIN	Uncharacterized protein. (589 aa)
	F6RMR3_CIOIN	Uncharacterized protein. (576 aa)
	F6VSS4_CIOIN	Uncharacterized protein. (350 aa)
	Xbpc	BZIP domain-containing protein. (437 aa)
	F6QP81_CIOIN	Uncharacterized protein. (135 aa)
	F6TD07_CIOIN	Uncharacterized protein. (369 aa)
	F6ZXH0_CIOIN	Uncharacterized protein. (179 aa)
	F6SBJ2_CIOIN	Aldo_ket_red domain-containing protein. (299 aa)
	nox4	FAD-binding FR-type domain-containing protein. (811 aa)
	F6SLD6_CIOIN	Deacetylase sirtuin-type domain-containing protein. (737 aa)
	H2XKD1_CIOIN	Phosphotransferase. (471 aa)
	H2XM96_CIOIN	Aldo_ket_red domain-containing protein. (261 aa)
	H2XR59_CIOIN	Uncharacterized protein. (489 aa)
	H2XUD0_CIOIN	Phosphotransferase. (461 aa)
	H2XV38_CIOIN	Uncharacterized protein. (159 aa)
	H2Y0Q7_CIOIN	Na_Ca_ex domain-containing protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (185 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6R022_CIOIN	F6VSS4_CIOIN	ENSCINP00000020097	ENSCINP00000024330	Uncharacterized protein.	Uncharacterized protein.	0.513
F6RS66_CIOIN	F6SLD6_CIOIN	ENSCINP00000013103	ENSCINP00000027486	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Deacetylase sirtuin-type domain-containing protein.	0.539
F6RS66_CIOIN	LOC100184788	ENSCINP00000013103	ENSCINP00000006320	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase.	0.730
F6SBJ2_CIOIN	F6XH38_CIOIN	ENSCINP00000026337	ENSCINP00000007643	Aldo_ket_red domain-containing protein.	Uncharacterized protein.	0.973
F6SBJ2_CIOIN	F6ZGX7_CIOIN	ENSCINP00000026337	ENSCINP00000012248	Aldo_ket_red domain-containing protein.	Uncharacterized protein.	0.973
F6SBJ2_CIOIN	F6ZGZ0_CIOIN	ENSCINP00000026337	ENSCINP00000012246	Aldo_ket_red domain-containing protein.	Uncharacterized protein.	0.973
F6SBJ2_CIOIN	H2XM96_CIOIN	ENSCINP00000026337	ENSCINP00000030779	Aldo_ket_red domain-containing protein.	Aldo_ket_red domain-containing protein.	0.579
F6SLD6_CIOIN	F6RS66_CIOIN	ENSCINP00000027486	ENSCINP00000013103	Deacetylase sirtuin-type domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.539
F6SLD6_CIOIN	LOC100184788	ENSCINP00000027486	ENSCINP00000006320	Deacetylase sirtuin-type domain-containing protein.	Non-specific serine/threonine protein kinase.	0.548
F6SLD6_CIOIN	Sir2-d	ENSCINP00000027486	ENSCINP00000002463	Deacetylase sirtuin-type domain-containing protein.	Deacetylase sirtuin-type domain-containing protein.	0.590
F6SLD6_CIOIN	nox4	ENSCINP00000027486	ENSCINP00000026729	Deacetylase sirtuin-type domain-containing protein.	FAD-binding FR-type domain-containing protein.	0.475
F6VSS4_CIOIN	F6R022_CIOIN	ENSCINP00000024330	ENSCINP00000020097	Uncharacterized protein.	Uncharacterized protein.	0.513
F6XH38_CIOIN	F6SBJ2_CIOIN	ENSCINP00000007643	ENSCINP00000026337	Uncharacterized protein.	Aldo_ket_red domain-containing protein.	0.973
F6XH38_CIOIN	F6ZGX7_CIOIN	ENSCINP00000007643	ENSCINP00000012248	Uncharacterized protein.	Uncharacterized protein.	0.902
F6XH38_CIOIN	F6ZGZ0_CIOIN	ENSCINP00000007643	ENSCINP00000012246	Uncharacterized protein.	Uncharacterized protein.	0.902
F6XH38_CIOIN	H2XM96_CIOIN	ENSCINP00000007643	ENSCINP00000030779	Uncharacterized protein.	Aldo_ket_red domain-containing protein.	0.878
F6Y4X1_CIOIN	H2Y0Q7_CIOIN	ENSCINP00000019947	ENSCINP00000035491	Na_Ca_ex domain-containing protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.	Na_Ca_ex domain-containing protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.	0.943
F6YLI3_CIOIN	F6Z326_CIOIN	ENSCINP00000013803	ENSCINP00000022455	Phosphotransferase.	Uncharacterized protein.	0.865
F6YLI3_CIOIN	F7AZD3_CIOIN	ENSCINP00000013803	ENSCINP00000019213	Phosphotransferase.	Glucose-6-phosphate isomerase; Belongs to the GPI family.	0.978
F6YLI3_CIOIN	H2XKD1_CIOIN	ENSCINP00000013803	ENSCINP00000030113	Phosphotransferase.	Phosphotransferase.	0.903