(24 nodes) Multi-multicellular organism process network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	F7AAV2_CIOIN	EGF-like domain-containing protein. (618 aa)
	H2Y2G5_CIOIN	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (160 aa)
	H2Y1T8_CIOIN	G_PROTEIN_RECEP_F1_2 domain-containing protein. (149 aa)
	H2Y0R6_CIOIN	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (227 aa)
	H2Y0K5_CIOIN	Uncharacterized protein. (173 aa)
	H2XUF7_CIOIN	Uncharacterized protein. (212 aa)
	LOC100175802	Peroxiredoxin-like. (235 aa)
	H2XTY2_CIOIN	Uncharacterized protein. (882 aa)
	H2XT39_CIOIN	Uncharacterized protein. (494 aa)
	H2XRM3_CIOIN	Uncharacterized protein. (212 aa)
	ppar	Nuclear receptor. (644 aa)
	LOC100176678	PITH domain-containing protein 1. (209 aa)
	LOC100186815	Insulin-like growth factor-binding protein 5. (225 aa)
	F6R3M6_CIOIN	Uncharacterized protein. (741 aa)
	LOC100176668	Transmembrane emp24 domain-containing protein 2. (203 aa)
	F6ZJ88_CIOIN	Uncharacterized protein. (341 aa)
	F6SDP7_CIOIN	EGF-like domain-containing protein. (628 aa)
	zf(c2h2)-46	Zinc finger protein (C2H2)-46. (600 aa)
	F6TT57_CIOIN	Uncharacterized protein. (762 aa)
	F6RJQ4_CIOIN	Uncharacterized protein. (333 aa)
	LOC100179396	Integrin beta. (751 aa)
	LOC100183393	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1141 aa)
	Cimsi	Uncharacterized protein. (393 aa)
	LOC100184817	Growth hormone secretagogue receptor type 1-like. (366 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cimsi	H2Y0K5_CIOIN	ENSCINP00000006896	ENSCINP00000035439	Uncharacterized protein.	Uncharacterized protein.	0.901
F6SDP7_CIOIN	F6TT57_CIOIN	ENSCINP00000012732	ENSCINP00000008859	EGF-like domain-containing protein.	Uncharacterized protein.	0.681
F6SDP7_CIOIN	F7AAV2_CIOIN	ENSCINP00000012732	ENSCINP00000023392	EGF-like domain-containing protein.	EGF-like domain-containing protein.	0.902
F6TT57_CIOIN	F6SDP7_CIOIN	ENSCINP00000008859	ENSCINP00000012732	Uncharacterized protein.	EGF-like domain-containing protein.	0.681
F6TT57_CIOIN	F7AAV2_CIOIN	ENSCINP00000008859	ENSCINP00000023392	Uncharacterized protein.	EGF-like domain-containing protein.	0.681
F7AAV2_CIOIN	F6SDP7_CIOIN	ENSCINP00000023392	ENSCINP00000012732	EGF-like domain-containing protein.	EGF-like domain-containing protein.	0.902
F7AAV2_CIOIN	F6TT57_CIOIN	ENSCINP00000023392	ENSCINP00000008859	EGF-like domain-containing protein.	Uncharacterized protein.	0.681
H2Y0K5_CIOIN	Cimsi	ENSCINP00000035439	ENSCINP00000006896	Uncharacterized protein.	Uncharacterized protein.	0.901
H2Y0R6_CIOIN	H2Y2G5_CIOIN	ENSCINP00000035500	ENSCINP00000036100	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.633
H2Y0R6_CIOIN	LOC100183393	ENSCINP00000035500	ENSCINP00000006863	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.657
H2Y0R6_CIOIN	ppar	ENSCINP00000035500	ENSCINP00000024308	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Nuclear receptor.	0.449
H2Y2G5_CIOIN	H2Y0R6_CIOIN	ENSCINP00000036100	ENSCINP00000035500	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.633
H2Y2G5_CIOIN	LOC100183393	ENSCINP00000036100	ENSCINP00000006863	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.657
H2Y2G5_CIOIN	ppar	ENSCINP00000036100	ENSCINP00000024308	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Nuclear receptor.	0.449
LOC100183393	H2Y0R6_CIOIN	ENSCINP00000006863	ENSCINP00000035500	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.657
LOC100183393	H2Y2G5_CIOIN	ENSCINP00000006863	ENSCINP00000036100	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.657
ppar	H2Y0R6_CIOIN	ENSCINP00000024308	ENSCINP00000035500	Nuclear receptor.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.449
ppar	H2Y2G5_CIOIN	ENSCINP00000024308	ENSCINP00000036100	Nuclear receptor.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.449