(30 nodes) DNA-templated DNA replication maintenance of fidelity network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	F6PLC9_CIOIN	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (128 aa)
	LOC100182716	Flap endonuclease GEN homolog 1. (709 aa)
	F6T7M7_CIOIN	Uncharacterized protein. (492 aa)
	F6USX3_CIOIN	Uncharacterized protein. (983 aa)
	H2XXS5_CIOIN	Uncharacterized protein. (440 aa)
	H2XWC2_CIOIN	DUF2439 domain-containing protein. (221 aa)
	H2XVZ6_CIOIN	Uncharacterized protein. (436 aa)
	H2XN42_CIOIN	Uncharacterized protein. (362 aa)
	H2XN24_CIOIN	PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family. (158 aa)
	H2Y1C1_CIOIN	Uncharacterized protein. (801 aa)
	LOC100185652	Mre11_DNA_bind domain-containing protein; Belongs to the MRE11/RAD32 family. (530 aa)
	F6TV58_CIOIN	Uncharacterized protein. (147 aa)
	F6YH93_CIOIN	Uncharacterized protein. (1111 aa)
	F6PL57_CIOIN	Uncharacterized protein. (1087 aa)
	F6QXW9_CIOIN	Helicase ATP-binding domain-containing protein. (273 aa)
	LOC100178968	DNA polymerase. (1064 aa)
	LOC100179894	Werner syndrome ATP-dependent helicase homolog isoform X1. (1194 aa)
	F6UM67_CIOIN	RING-type domain-containing protein. (762 aa)
	F6W3X7_CIOIN	ANK_REP_REGION domain-containing protein. (509 aa)
	F6W461_CIOIN	Uncharacterized protein. (211 aa)
	F6Y0T9_CIOIN	HD domain-containing protein. (481 aa)
	H2Y0F9_CIOIN	Uncharacterized protein. (82 aa)
	F6YN96_CIOIN	3'-5' exonuclease domain-containing protein. (573 aa)
	F6YYK3_CIOIN	Uncharacterized protein. (583 aa)
	F7AWL5_CIOIN	F-box domain-containing protein. (431 aa)
	F6UAB2_CIOIN	FANCM-MHF_bd domain-containing protein. (274 aa)
	F6WUQ7_CIOIN	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2157 aa)
	F6XHT6_CIOIN	UvrD-like helicase C-terminal domain-containing protein. (212 aa)
	F6ZN89_CIOIN	Uncharacterized protein; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (627 aa)
	H2XJT4_CIOIN	PHD-type domain-containing protein. (508 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6PL57_CIOIN	F6QXW9_CIOIN	ENSCINP00000006244	ENSCINP00000006094	Uncharacterized protein.	Helicase ATP-binding domain-containing protein.	0.482
F6PL57_CIOIN	F6UAB2_CIOIN	ENSCINP00000006244	ENSCINP00000021425	Uncharacterized protein.	FANCM-MHF_bd domain-containing protein.	0.482
F6PL57_CIOIN	H2XN42_CIOIN	ENSCINP00000006244	ENSCINP00000031075	Uncharacterized protein.	Uncharacterized protein.	0.482
F6PL57_CIOIN	LOC100179894	ENSCINP00000006244	ENSCINP00000004562	Uncharacterized protein.	Werner syndrome ATP-dependent helicase homolog isoform X1.	0.547
F6PLC9_CIOIN	F6UM67_CIOIN	ENSCINP00000018210	ENSCINP00000003190	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.	RING-type domain-containing protein.	0.494
F6PLC9_CIOIN	F6WUQ7_CIOIN	ENSCINP00000018210	ENSCINP00000019635	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.894
F6PLC9_CIOIN	F6XHT6_CIOIN	ENSCINP00000018210	ENSCINP00000019609	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.	UvrD-like helicase C-terminal domain-containing protein.	0.480
F6PLC9_CIOIN	F6YH93_CIOIN	ENSCINP00000018210	ENSCINP00000008456	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.	Uncharacterized protein.	0.998
F6PLC9_CIOIN	F6ZN89_CIOIN	ENSCINP00000018210	ENSCINP00000018923	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.	Uncharacterized protein; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily.	0.515
F6PLC9_CIOIN	F7AWL5_CIOIN	ENSCINP00000018210	ENSCINP00000023021	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.	F-box domain-containing protein.	0.480
F6PLC9_CIOIN	H2XVZ6_CIOIN	ENSCINP00000018210	ENSCINP00000033830	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.	Uncharacterized protein.	0.887
F6PLC9_CIOIN	LOC100178968	ENSCINP00000018210	ENSCINP00000005791	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.	DNA polymerase.	0.566
F6PLC9_CIOIN	LOC100179894	ENSCINP00000018210	ENSCINP00000004562	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.	Werner syndrome ATP-dependent helicase homolog isoform X1.	0.739
F6QXW9_CIOIN	F6PL57_CIOIN	ENSCINP00000006094	ENSCINP00000006244	Helicase ATP-binding domain-containing protein.	Uncharacterized protein.	0.482
F6QXW9_CIOIN	F6TV58_CIOIN	ENSCINP00000006094	ENSCINP00000008579	Helicase ATP-binding domain-containing protein.	Uncharacterized protein.	0.707
F6QXW9_CIOIN	F6UAB2_CIOIN	ENSCINP00000006094	ENSCINP00000021425	Helicase ATP-binding domain-containing protein.	FANCM-MHF_bd domain-containing protein.	0.822
F6QXW9_CIOIN	F6USX3_CIOIN	ENSCINP00000006094	ENSCINP00000011520	Helicase ATP-binding domain-containing protein.	Uncharacterized protein.	0.794
F6QXW9_CIOIN	F6WUQ7_CIOIN	ENSCINP00000006094	ENSCINP00000019635	Helicase ATP-binding domain-containing protein.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.723
F6QXW9_CIOIN	F6XHT6_CIOIN	ENSCINP00000006094	ENSCINP00000019609	Helicase ATP-binding domain-containing protein.	UvrD-like helicase C-terminal domain-containing protein.	0.896
F6QXW9_CIOIN	F6YH93_CIOIN	ENSCINP00000006094	ENSCINP00000008456	Helicase ATP-binding domain-containing protein.	Uncharacterized protein.	0.637