(12 nodes) Actin nucleation network (Ciona intestinalis)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Predicted Interactions

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Your Input:
	LOC100176247	Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (179 aa)
	LOC100179260	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (300 aa)
	F6QHA4_CIOIN	Uncharacterized protein. (92 aa)
	F7ACG4_CIOIN	WH2 domain-containing protein. (460 aa)
	LOC100182145	Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (366 aa)
	F6ZNL7_CIOIN	FH2 domain-containing protein. (158 aa)
	LOC100185040	Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (150 aa)
	H2XKR2_CIOIN	Uncharacterized protein. (99 aa)
	H2XKH1_CIOIN	FH2 domain-containing protein. (302 aa)
	F6WWY7_CIOIN	KIND domain-containing protein. (615 aa)
	H2XW16_CIOIN	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (216 aa)
	ar20	Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (168 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6QHA4_CIOIN	H2XKR2_CIOIN	ENSCINP00000016912	ENSCINP00000030244	Uncharacterized protein.	Uncharacterized protein.	0.953
F6QHA4_CIOIN	H2XW16_CIOIN	ENSCINP00000016912	ENSCINP00000033850	Uncharacterized protein.	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	0.994
F6QHA4_CIOIN	LOC100176247	ENSCINP00000016912	ENSCINP00000003763	Uncharacterized protein.	Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	0.986
F6QHA4_CIOIN	LOC100179260	ENSCINP00000016912	ENSCINP00000002402	Uncharacterized protein.	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	0.993
F6QHA4_CIOIN	LOC100182145	ENSCINP00000016912	ENSCINP00000009296	Uncharacterized protein.	Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	0.988
F6QHA4_CIOIN	LOC100185040	ENSCINP00000016912	ENSCINP00000032174	Uncharacterized protein.	Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.	0.982
F6QHA4_CIOIN	ar20	ENSCINP00000016912	ENSCINP00000033932	Uncharacterized protein.	Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family.	0.987
F6WWY7_CIOIN	F6ZNL7_CIOIN	ENSCINP00000019382	ENSCINP00000006646	KIND domain-containing protein.	FH2 domain-containing protein.	0.662
F6WWY7_CIOIN	H2XKH1_CIOIN	ENSCINP00000019382	ENSCINP00000030153	KIND domain-containing protein.	FH2 domain-containing protein.	0.662
F6ZNL7_CIOIN	F6WWY7_CIOIN	ENSCINP00000006646	ENSCINP00000019382	FH2 domain-containing protein.	KIND domain-containing protein.	0.662
F6ZNL7_CIOIN	F7ACG4_CIOIN	ENSCINP00000006646	ENSCINP00000011087	FH2 domain-containing protein.	WH2 domain-containing protein.	0.414
F7ACG4_CIOIN	F6ZNL7_CIOIN	ENSCINP00000011087	ENSCINP00000006646	WH2 domain-containing protein.	FH2 domain-containing protein.	0.414
F7ACG4_CIOIN	H2XKH1_CIOIN	ENSCINP00000011087	ENSCINP00000030153	WH2 domain-containing protein.	FH2 domain-containing protein.	0.414
H2XKH1_CIOIN	F6WWY7_CIOIN	ENSCINP00000030153	ENSCINP00000019382	FH2 domain-containing protein.	KIND domain-containing protein.	0.662
H2XKH1_CIOIN	F7ACG4_CIOIN	ENSCINP00000030153	ENSCINP00000011087	FH2 domain-containing protein.	WH2 domain-containing protein.	0.414
H2XKR2_CIOIN	F6QHA4_CIOIN	ENSCINP00000030244	ENSCINP00000016912	Uncharacterized protein.	Uncharacterized protein.	0.953
H2XKR2_CIOIN	H2XW16_CIOIN	ENSCINP00000030244	ENSCINP00000033850	Uncharacterized protein.	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	0.991
H2XKR2_CIOIN	LOC100176247	ENSCINP00000030244	ENSCINP00000003763	Uncharacterized protein.	Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	0.981
H2XKR2_CIOIN	LOC100179260	ENSCINP00000030244	ENSCINP00000002402	Uncharacterized protein.	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	0.986
H2XKR2_CIOIN	LOC100182145	ENSCINP00000030244	ENSCINP00000009296	Uncharacterized protein.	Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	0.985