(54 nodes) Basal part of cell network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100178633	Protein OSCP1-like. (368 aa)
	H2XYW7_CIOIN	Uncharacterized protein. (149 aa)
	H2XZT3_CIOIN	Uncharacterized protein. (121 aa)
	H2Y3R9_CIOIN	Peptidase_M16_M domain-containing protein. (167 aa)
	H2Y0K6_CIOIN	Uncharacterized protein. (3252 aa)
	F6V725_CIOIN	PDZ domain-containing protein. (141 aa)
	F6YCG7_CIOIN	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1086 aa)
	LOC100175978	Proton-coupled folate transporter. (455 aa)
	LOC100179961	Recep_L_domain domain-containing protein. (200 aa)
	LOC100183420	Uncharacterized protein. (224 aa)
	LOC778964	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (880 aa)
	F6YJ69_CIOIN	Uncharacterized protein. (471 aa)
	F6YJ55_CIOIN	Uncharacterized protein. (496 aa)
	F6VXA3_CIOIN	Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. (533 aa)
	F6ZIB9_CIOIN	ABC transporter domain-containing protein. (291 aa)
	F6WSQ4_CIOIN	TOG domain-containing protein. (201 aa)
	F6W6K9_CIOIN	Uncharacterized protein. (1344 aa)
	F6XQV0_CIOIN	Vitellogenin domain-containing protein. (896 aa)
	Egfr1	Receptor protein-tyrosine kinase. (1462 aa)
	LOC100179396	Integrin beta. (751 aa)
	F6S2G5_CIOIN	Calponin-homology (CH) domain-containing protein. (231 aa)
	LOC100178767	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (587 aa)
	kcnq1	Uncharacterized protein; Belongs to the potassium channel family. (520 aa)
	F6XCJ0_CIOIN	Uncharacterized protein. (289 aa)
	F6V2Z5_CIOIN	Uncharacterized protein. (1293 aa)
	LOC100176657	Claudin-1. (232 aa)
	F6PV66_CIOIN	PH domain-containing protein. (661 aa)
	F6PGX9_CIOIN	Uncharacterized protein. (1230 aa)
	F6UN86_CIOIN	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (477 aa)
	F6ZBU1_CIOIN	ABC transmembrane type-1 domain-containing protein. (296 aa)
	F6U7R9_CIOIN	Uncharacterized protein. (1408 aa)
	LOC100181021	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (200 aa)
	F6R4U4_CIOIN	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (187 aa)
	F7B059_CIOIN	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (422 aa)
	gla1	Uncharacterized protein LOC780869. (554 aa)
	F6SXP0_CIOIN	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (144 aa)
	LOC100183825	Organic solute transporter subunit alpha-like. (378 aa)
	F6WM68_CIOIN	Uncharacterized protein. (172 aa)
	F6W0A5_CIOIN	Uncharacterized protein. (378 aa)
	F6W067_CIOIN	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (426 aa)
	F7BGU9_CIOIN	Uncharacterized protein. (267 aa)
	F7AK59_CIOIN	Uncharacterized protein. (531 aa)
	H2XJT6_CIOIN	ABC transmembrane type-1 domain-containing protein. (229 aa)
	LOC100183075	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (215 aa)
	H2XKV3_CIOIN	PDZ domain-containing protein. (572 aa)
	H2XNH4_CIOIN	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (215 aa)
	H2XP79_CIOIN	Uncharacterized protein. (96 aa)
	H2XQ24_CIOIN	Uncharacterized protein. (377 aa)
	H2XQT4_CIOIN	Uncharacterized protein. (321 aa)
	H2XSG9_CIOIN	EGF-like domain-containing protein. (223 aa)
	H2XT83_CIOIN	Uncharacterized protein. (416 aa)
	LOC100177737	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (161 aa)
	H2XWF3_CIOIN	MFS domain-containing protein. (409 aa)
	H2XY70_CIOIN	Recep_L_domain domain-containing protein. (209 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Egfr1	F6UN86_CIOIN	ENSCINP00000006067	ENSCINP00000013966	Receptor protein-tyrosine kinase.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.737
Egfr1	H2XKV3_CIOIN	ENSCINP00000006067	ENSCINP00000030285	Receptor protein-tyrosine kinase.	PDZ domain-containing protein.	0.454
Egfr1	H2XP79_CIOIN	ENSCINP00000006067	ENSCINP00000031462	Receptor protein-tyrosine kinase.	Uncharacterized protein.	0.454
Egfr1	gla1	ENSCINP00000006067	ENSCINP00000019224	Receptor protein-tyrosine kinase.	Uncharacterized protein LOC780869.	0.736
F6U7R9_CIOIN	F6V725_CIOIN	ENSCINP00000014894	ENSCINP00000000086	Uncharacterized protein.	PDZ domain-containing protein.	0.755
F6UN86_CIOIN	Egfr1	ENSCINP00000013966	ENSCINP00000006067	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Receptor protein-tyrosine kinase.	0.737
F6UN86_CIOIN	H2XY70_CIOIN	ENSCINP00000013966	ENSCINP00000034604	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Recep_L_domain domain-containing protein.	0.736
F6UN86_CIOIN	LOC100179396	ENSCINP00000013966	ENSCINP00000006408	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Integrin beta.	0.550
F6UN86_CIOIN	LOC100179961	ENSCINP00000013966	ENSCINP00000001856	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Recep_L_domain domain-containing protein.	0.736
F6UN86_CIOIN	LOC100183420	ENSCINP00000013966	ENSCINP00000002277	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Uncharacterized protein.	0.961
F6UN86_CIOIN	LOC778964	ENSCINP00000013966	ENSCINP00000002343	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.754
F6UN86_CIOIN	gla1	ENSCINP00000013966	ENSCINP00000019224	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Uncharacterized protein LOC780869.	0.914
F6V725_CIOIN	F6U7R9_CIOIN	ENSCINP00000000086	ENSCINP00000014894	PDZ domain-containing protein.	Uncharacterized protein.	0.755
F6W067_CIOIN	F7B059_CIOIN	ENSCINP00000022282	ENSCINP00000017998	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.	0.558
F6W0A5_CIOIN	F6XCJ0_CIOIN	ENSCINP00000022277	ENSCINP00000011755	Uncharacterized protein.	Uncharacterized protein.	0.927
F6W0A5_CIOIN	H2Y3R9_CIOIN	ENSCINP00000022277	ENSCINP00000036554	Uncharacterized protein.	Peptidase_M16_M domain-containing protein.	0.944
F6W6K9_CIOIN	F6WSQ4_CIOIN	ENSCINP00000004080	ENSCINP00000004069	Uncharacterized protein.	TOG domain-containing protein.	0.821
F6WSQ4_CIOIN	F6W6K9_CIOIN	ENSCINP00000004069	ENSCINP00000004080	TOG domain-containing protein.	Uncharacterized protein.	0.821
F6XCJ0_CIOIN	F6W0A5_CIOIN	ENSCINP00000011755	ENSCINP00000022277	Uncharacterized protein.	Uncharacterized protein.	0.927
F6XCJ0_CIOIN	H2Y3R9_CIOIN	ENSCINP00000011755	ENSCINP00000036554	Uncharacterized protein.	Peptidase_M16_M domain-containing protein.	0.947