STRINGSTRING
F6V4V0_CIOIN F6V4V0_CIOIN F6SFW9_CIOIN F6SFW9_CIOIN Xbpc Xbpc F6YWM5_CIOIN F6YWM5_CIOIN LOC778708 LOC778708 F6VS24_CIOIN F6VS24_CIOIN F7BKY1_CIOIN F7BKY1_CIOIN LSM1 LSM1 LOC101242476 LOC101242476 F6PQS1_CIOIN F6PQS1_CIOIN LOC100187147 LOC100187147 F6ZX31_CIOIN F6ZX31_CIOIN Zf(c3h) Zf(c3h) LOC100182253 LOC100182253 F6Y6P2_CIOIN F6Y6P2_CIOIN F6U7G3_CIOIN F6U7G3_CIOIN F6SLD6_CIOIN F6SLD6_CIOIN LOC779004 LOC779004 F6W3W9_CIOIN F6W3W9_CIOIN F6X1D6_CIOIN F6X1D6_CIOIN F6T2G1_CIOIN F6T2G1_CIOIN H2XJG1_CIOIN H2XJG1_CIOIN LOC100180326 LOC100180326 LOC100186675 LOC100186675 LOC100178517 LOC100178517 H2XMV3_CIOIN H2XMV3_CIOIN Bmp2/4 Bmp2/4 H2XN97_CIOIN H2XN97_CIOIN dynlt1 dynlt1 H2XNX7_CIOIN H2XNX7_CIOIN H2XPA3_CIOIN H2XPA3_CIOIN H2XQD2_CIOIN H2XQD2_CIOIN H2XRZ5_CIOIN H2XRZ5_CIOIN LOC100187478 LOC100187478 H2XSV3_CIOIN H2XSV3_CIOIN H2XU53_CIOIN H2XU53_CIOIN H2XUB7_CIOIN H2XUB7_CIOIN H2XUU5_CIOIN H2XUU5_CIOIN LOC100179084 LOC100179084 hlx hlx H2XYC7_CIOIN H2XYC7_CIOIN H2XZ57_CIOIN H2XZ57_CIOIN LOC100179691 LOC100179691 H2XZI8_CIOIN H2XZI8_CIOIN H2Y0M3_CIOIN H2Y0M3_CIOIN H2Y0R6_CIOIN H2Y0R6_CIOIN H2Y1J5_CIOIN H2Y1J5_CIOIN H2Y1U3_CIOIN H2Y1U3_CIOIN LOC100179332 LOC100179332 H2Y2G5_CIOIN H2Y2G5_CIOIN H2Y2R4_CIOIN H2Y2R4_CIOIN H2Y3K7_CIOIN H2Y3K7_CIOIN F6TS32_CIOIN F6TS32_CIOIN F6RL50_CIOIN F6RL50_CIOIN Ci-ZF(ZZ)-7 Ci-ZF(ZZ)-7 LOC100181983 LOC100181983 soxE soxE noggin noggin F6VNT1_CIOIN F6VNT1_CIOIN Smoothened Smoothened LOC104265605 LOC104265605 LOC100177697 LOC100177697 F6YRG2_CIOIN F6YRG2_CIOIN F6UJF1_CIOIN F6UJF1_CIOIN mT mT gsk gsk p53/p73-a p53/p73-a P53/p73-b P53/p73-b Rev-erb Rev-erb F6QD80_CIOIN F6QD80_CIOIN Axin Axin LOC100187015 LOC100187015 F6TLB6_CIOIN F6TLB6_CIOIN LOC100180825 LOC100180825 LOC100186426 LOC100186426 F7B5N7_CIOIN F7B5N7_CIOIN Dll-a Dll-a LOC100181706 LOC100181706 F6RF18_CIOIN F6RF18_CIOIN F6R946_CIOIN F6R946_CIOIN F7B9G3_CIOIN F7B9G3_CIOIN L7N0S2_CIOIN L7N0S2_CIOIN myc myc Xbpa Xbpa sfrp2 sfrp2 LOC100176196 LOC100176196 Zf(cxxc)-5 Zf(cxxc)-5 meis meis smad4 smad4 Ephrin-a Ephrin-a F6VVA7_CIOIN F6VVA7_CIOIN LOC100185251-2 LOC100185251-2 F6WF44_CIOIN F6WF44_CIOIN F6T2W0_CIOIN F6T2W0_CIOIN F6SGS4_CIOIN F6SGS4_CIOIN F6ZG18_CIOIN F6ZG18_CIOIN F6RJ81_CIOIN F6RJ81_CIOIN LOC100181289 LOC100181289 LOC100184818 LOC100184818 F6YAC3_CIOIN F6YAC3_CIOIN F6UL80_CIOIN F6UL80_CIOIN xbpd xbpd F6X4F9_CIOIN F6X4F9_CIOIN F7A9X0_CIOIN F7A9X0_CIOIN LOC100178394 LOC100178394 zf(c2h2)-129 zf(c2h2)-129 LOC494392 LOC494392 LOC100180348 LOC100180348 snail snail Mist Mist F6PKT6_CIOIN F6PKT6_CIOIN LOC100175816 LOC100175816 smad6/7 smad6/7 F6R6J0_CIOIN F6R6J0_CIOIN LOC100186815 LOC100186815 LOC100177957 LOC100177957 cbfb cbfb F6WYD9_CIOIN F6WYD9_CIOIN F6ZDN3_CIOIN F6ZDN3_CIOIN F7ACP0_CIOIN F7ACP0_CIOIN gabpalpha gabpalpha F6ZUG2_CIOIN F6ZUG2_CIOIN F6X941_CIOIN F6X941_CIOIN LOC100178798 LOC100178798 F7AVR1_CIOIN F7AVR1_CIOIN F6PZR6_CIOIN F6PZR6_CIOIN F6RH73_CIOIN F6RH73_CIOIN wnt3 wnt3 LOC100177537 LOC100177537 F6T4G2_CIOIN F6T4G2_CIOIN F6ZHF5_CIOIN F6ZHF5_CIOIN ppar ppar F6V5K2_CIOIN F6V5K2_CIOIN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
F6V4V0_CIOINSortilin. (1459 aa)
F6SFW9_CIOINFork-head domain-containing protein. (470 aa)
XbpcBZIP domain-containing protein. (437 aa)
F6YWM5_CIOINBHLH domain-containing protein. (96 aa)
LOC778708BHLH domain-containing protein. (792 aa)
F6VS24_CIOINSema domain-containing protein. (152 aa)
F7BKY1_CIOINSema domain-containing protein. (229 aa)
LSM1U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs. (132 aa)
LOC101242476Glioma pathogenesis-related protein 1-like; Belongs to the CRISP family. (336 aa)
F6PQS1_CIOINProtein kinase domain-containing protein. (190 aa)
LOC100187147Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer. (158 aa)
F6ZX31_CIOINSema domain-containing protein; Belongs to the semaphorin family. (292 aa)
Zf(c3h)Uncharacterized protein. (380 aa)
LOC100182253Steroid receptor RNA activator 1-like. (187 aa)
F6Y6P2_CIOINSema domain-containing protein; Belongs to the semaphorin family. (483 aa)
F6U7G3_CIOINHMG box domain-containing protein. (364 aa)
F6SLD6_CIOINDeacetylase sirtuin-type domain-containing protein. (737 aa)
LOC779004Transcription factor protein. (553 aa)
F6W3W9_CIOINUncharacterized protein. (758 aa)
F6X1D6_CIOINRWD domain-containing protein. (156 aa)
F6T2G1_CIOINUncharacterized protein. (298 aa)
H2XJG1_CIOINRING-type domain-containing protein. (147 aa)
LOC100180326Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
LOC100186675AP-1 complex-associated regulatory protein isoform X1. (287 aa)
LOC100178517Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (142 aa)
H2XMV3_CIOINFibrinogen C-terminal domain-containing protein. (229 aa)
Bmp2/4TGFb_propeptide domain-containing protein. (376 aa)
H2XN97_CIOINUncharacterized protein. (200 aa)
dynlt1Tctex1-related dynein light chain. (113 aa)
H2XNX7_CIOINPCM1_C domain-containing protein. (324 aa)
H2XPA3_CIOINRas-GEF domain-containing protein. (451 aa)
H2XQD2_CIOINCRAL-TRIO domain-containing protein. (242 aa)
H2XRZ5_CIOINUncharacterized protein. (217 aa)
LOC100187478dnaJ homolog subfamily B member 11-like. (360 aa)
H2XSV3_CIOINSortilin-Vps10 domain-containing protein. (276 aa)
H2XU53_CIOINUncharacterized protein; Belongs to the heat shock protein 70 family. (643 aa)
H2XUB7_CIOINSortilin-Vps10 domain-containing protein. (205 aa)
H2XUU5_CIOINUncharacterized protein. (532 aa)
LOC100179084CRAL-TRIO domain-containing protein. (230 aa)
hlxHomeobox domain-containing protein. (554 aa)
H2XYC7_CIOINUncharacterized protein. (197 aa)
H2XZ57_CIOINUncharacterized protein. (229 aa)
LOC100179691Bifunctional lysine-specific demethylase and histidyl-hydroxylase; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. (458 aa)
H2XZI8_CIOINCRAL-TRIO domain-containing protein. (235 aa)
H2Y0M3_CIOINCHRD domain-containing protein. (251 aa)
H2Y0R6_CIOINMediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (227 aa)
H2Y1J5_CIOINUncharacterized protein. (448 aa)
H2Y1U3_CIOINProtein kinase domain-containing protein. (1156 aa)
LOC100179332semaphorin-4G-like isoform X3; Belongs to the semaphorin family. (793 aa)
H2Y2G5_CIOINMediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (160 aa)
H2Y2R4_CIOINUncharacterized protein. (167 aa)
H2Y3K7_CIOINFibrinogen C-terminal domain-containing protein. (218 aa)
F6TS32_CIOINc-SKI_SMAD_bind domain-containing protein. (624 aa)
F6RL50_CIOINUncharacterized protein. (303 aa)
Ci-ZF(ZZ)-7Zinc finger protein. (619 aa)
LOC100181983PRKC apoptosis WT1 regulator protein-like. (304 aa)
soxESoxE protein. (808 aa)
nogginNoggin protein precursor. (219 aa)
F6VNT1_CIOINUncharacterized protein. (229 aa)
SmoothenedUncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (441 aa)
LOC104265605Uncharacterized protein. (575 aa)
LOC100177697Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (236 aa)
F6YRG2_CIOINCaveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (211 aa)
F6UJF1_CIOINUDENN FLCN/SMCR8-type domain-containing protein. (561 aa)
mTUncharacterized protein. (812 aa)
gskGlycogen synthase kinase Alpha/beta. (407 aa)
p53/p73-aTranscription factor protein. (489 aa)
P53/p73-bUncharacterized protein. (419 aa)
Rev-erbUncharacterized protein. (597 aa)
F6QD80_CIOINSCP domain-containing protein; Belongs to the CRISP family. (201 aa)
AxinUncharacterized protein. (643 aa)
LOC100187015RING finger protein 10 isoform X2. (695 aa)
F6TLB6_CIOINUncharacterized protein. (891 aa)
LOC100180825RING-type domain-containing protein. (215 aa)
LOC100186426Negative elongation factor B. (605 aa)
F7B5N7_CIOINProtein kinase domain-containing protein. (353 aa)
Dll-aHomeobox domain-containing protein. (453 aa)
LOC100181706Peptidase inhibitor 16 isoform X3; Belongs to the CRISP family. (403 aa)
F6RF18_CIOINUncharacterized protein. (5108 aa)
F6R946_CIOINUncharacterized protein. (246 aa)
F7B9G3_CIOINTGF_BETA_2 domain-containing protein. (387 aa)
L7N0S2_CIOINUncharacterized protein. (175 aa)
mycTranscription factor protein isoform X1. (681 aa)
XbpaBZIP domain-containing protein. (309 aa)
sfrp2Secreted frizzled-related protein isoform X1. (293 aa)
LOC100176196Protein RCC2 homolog. (475 aa)
Zf(cxxc)-5Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1257 aa)
meisHomeobox domain-containing protein. (554 aa)
smad4Mothers against decapentaplegic homolog. (527 aa)
Ephrin-aEphrin RBD domain-containing protein; Belongs to the ephrin family. (248 aa)
F6VVA7_CIOINHomeobox domain-containing protein. (403 aa)
LOC100185251-2Zinc finger protein. (339 aa)
F6WF44_CIOINFibrinogen C-terminal domain-containing protein. (187 aa)
F6T2W0_CIOINUncharacterized protein. (388 aa)
F6SGS4_CIOINUncharacterized protein. (229 aa)
F6ZG18_CIOINFERM domain-containing protein. (589 aa)
F6RJ81_CIOINANK_REP_REGION domain-containing protein. (400 aa)
LOC100181289Cyclin-dependent-like kinase 5; Belongs to the protein kinase superfamily. (292 aa)
LOC100184818Uncharacterized protein. (583 aa)
F6YAC3_CIOINSenescence domain-containing protein. (116 aa)
F6UL80_CIOINHomeobox domain-containing protein. (287 aa)
xbpdTranscription factor protein isoform X1. (366 aa)
F6X4F9_CIOINUncharacterized protein. (262 aa)
F7A9X0_CIOINProtein kinase domain-containing protein. (772 aa)
LOC100178394F-box only protein 7. (515 aa)
zf(c2h2)-129Zinc finger protein ZF(C2H2)-129 isoform X1. (687 aa)
LOC494392Uncharacterized protein LOC494392. (131 aa)
LOC100180348B-cell CLL/lymphoma 7 protein family member B-like. (167 aa)
snailUncharacterized protein. (584 aa)
MistBHLH domain-containing protein. (550 aa)
F6PKT6_CIOINRNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (822 aa)
LOC100175816TPR_REGION domain-containing protein. (1034 aa)
smad6/7Mothers against decapentaplegic homolog. (361 aa)
F6R6J0_CIOINUncharacterized protein. (585 aa)
LOC100186815Insulin-like growth factor-binding protein 5. (225 aa)
LOC100177957Tyrosine-protein kinase RYK. (593 aa)
cbfbCore-binding factor, b subunit isoform X1. (181 aa)
F6WYD9_CIOINUncharacterized protein. (584 aa)
F6ZDN3_CIOINSema domain-containing protein. (427 aa)
F7ACP0_CIOINUncharacterized protein. (301 aa)
gabpalphaGA repeat binding protein alpha homolog. (364 aa)
F6ZUG2_CIOINUncharacterized protein. (150 aa)
F6X941_CIOINUncharacterized protein. (296 aa)
LOC100178798PKS_ER domain-containing protein. (378 aa)
F7AVR1_CIOINHomeobox domain-containing protein. (418 aa)
F6PZR6_CIOINUncharacterized protein. (728 aa)
F6RH73_CIOINUncharacterized protein. (384 aa)
wnt3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (304 aa)
LOC100177537Protein kinase domain-containing protein. (1105 aa)
F6T4G2_CIOINN_BRCA1_IG domain-containing protein. (218 aa)
F6ZHF5_CIOINProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (369 aa)
pparNuclear receptor. (644 aa)
F6V5K2_CIOINUncharacterized protein. (467 aa)
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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