STRINGSTRING
H2XRP4_CIOIN H2XRP4_CIOIN Tgfbr-iib Tgfbr-iib tgfbr-iia tgfbr-iia LOC100179981 LOC100179981 cdc42 cdc42 LOC100176290 LOC100176290 LOC100187261 LOC100187261 LOC100176958 LOC100176958 soxE soxE Zf(c2h2)-69 Zf(c2h2)-69 Sir2-d Sir2-d Smoothened Smoothened F6VK85_CIOIN F6VK85_CIOIN LOC100184368 LOC100184368 tgfbr-ia tgfbr-ia LOC100178597 LOC100178597 p53/p73-a p53/p73-a F6WSD2_CIOIN F6WSD2_CIOIN F6W6K0_CIOIN F6W6K0_CIOIN LOC778720 LOC778720 P53/p73-b P53/p73-b F6W2W8_CIOIN F6W2W8_CIOIN F6YDG1_CIOIN F6YDG1_CIOIN F6SCE7_CIOIN F6SCE7_CIOIN F6PPJ1_CIOIN F6PPJ1_CIOIN F7BBL3_CIOIN F7BBL3_CIOIN F7BBJ6_CIOIN F7BBJ6_CIOIN LOC100182260 LOC100182260 LOC100178220 LOC100178220 F6WMR0_CIOIN F6WMR0_CIOIN smyd1 smyd1 F7BHR3_CIOIN F7BHR3_CIOIN LOC100178665 LOC100178665 F6ZM08_CIOIN F6ZM08_CIOIN F6RYG5_CIOIN F6RYG5_CIOIN neurogenin neurogenin F7B6D7_CIOIN F7B6D7_CIOIN otp otp LOC100179870 LOC100179870 LOC100181085 LOC100181085 Dll-a Dll-a LOC100181221 LOC100181221 zf(c2h2)-102 zf(c2h2)-102 Numb Numb Xbpa Xbpa LOC100178307 LOC100178307 sfrp2 sfrp2 LOC100181891 LOC100181891 smad4 smad4 F6ZQY6_CIOIN F6ZQY6_CIOIN tgfbr-ib tgfbr-ib LOC100185251-2 LOC100185251-2 F6ZG18_CIOIN F6ZG18_CIOIN F6ZFJ9_CIOIN F6ZFJ9_CIOIN F6SDP7_CIOIN F6SDP7_CIOIN F7BL69_CIOIN F7BL69_CIOIN LOC100178575 LOC100178575 F6YC82_CIOIN F6YC82_CIOIN F6PSM8_CIOIN F6PSM8_CIOIN F6RS66_CIOIN F6RS66_CIOIN F6RJA6_CIOIN F6RJA6_CIOIN F6RI21_CIOIN F6RI21_CIOIN LOC100187100 LOC100187100 Zf(c2h2)-33 Zf(c2h2)-33 Cibeta-catenin Cibeta-catenin myod myod F6UMA7_CIOIN F6UMA7_CIOIN xbpd xbpd F6YIR3_CIOIN F6YIR3_CIOIN LOC100185086 LOC100185086 F6VXC2_CIOIN F6VXC2_CIOIN F6X4F9_CIOIN F6X4F9_CIOIN F6THB4_CIOIN F6THB4_CIOIN soxC soxC F6QTW3_CIOIN F6QTW3_CIOIN LOC100183284 LOC100183284 Tgfbeta2 Tgfbeta2 F6UDR5_CIOIN F6UDR5_CIOIN F6T283_CIOIN F6T283_CIOIN Ci-Net Ci-Net snail snail F6R6C4_CIOIN F6R6C4_CIOIN cbfb cbfb rngi rngi Fgf8/17/18 Fgf8/17/18 e12/e47 e12/e47 F6UX10_CIOIN F6UX10_CIOIN F7ABT2_CIOIN F7ABT2_CIOIN xbpb xbpb tgfbeta-na4 tgfbeta-na4 F6TBG7_CIOIN F6TBG7_CIOIN Q4H307_CIOIN Q4H307_CIOIN F6WM20_CIOIN F6WM20_CIOIN F6YJE0_CIOIN F6YJE0_CIOIN F6VYF2_CIOIN F6VYF2_CIOIN LOC100179144 LOC100179144 LOC100178690 LOC100178690 F6UIG7_CIOIN F6UIG7_CIOIN F7AVR1_CIOIN F7AVR1_CIOIN F7AAV2_CIOIN F7AAV2_CIOIN LOC100176678 LOC100176678 F6WQL4_CIOIN F6WQL4_CIOIN F6RLL0_CIOIN F6RLL0_CIOIN wnt3 wnt3 F6V7C2_CIOIN F6V7C2_CIOIN F6TTH0_CIOIN F6TTH0_CIOIN F6YXX9_CIOIN F6YXX9_CIOIN F6V476_CIOIN F6V476_CIOIN F6SFW9_CIOIN F6SFW9_CIOIN Xbpc Xbpc F6YWM5_CIOIN F6YWM5_CIOIN F7B221_CIOIN F7B221_CIOIN F6PQC6_CIOIN F6PQC6_CIOIN F6TZA7_CIOIN F6TZA7_CIOIN F7AFQ9_CIOIN F7AFQ9_CIOIN Klf2 Klf2 F6SYE0_CIOIN F6SYE0_CIOIN F6YSG2_CIOIN F6YSG2_CIOIN F6U7G3_CIOIN F6U7G3_CIOIN F6SLD6_CIOIN F6SLD6_CIOIN LOC779004 LOC779004 F7AK80_CIOIN F7AK80_CIOIN F7AIB9_CIOIN F7AIB9_CIOIN H2XKM4_CIOIN H2XKM4_CIOIN H2XM17_CIOIN H2XM17_CIOIN Q1RPY5_CIOIN Q1RPY5_CIOIN LOC100181388 LOC100181388 Bmp2/4 Bmp2/4 H2XN97_CIOIN H2XN97_CIOIN H2XPA3_CIOIN H2XPA3_CIOIN H2XPL3_CIOIN H2XPL3_CIOIN H2XQ71_CIOIN H2XQ71_CIOIN H2XRZ5_CIOIN H2XRZ5_CIOIN srf srf H2XS27_CIOIN H2XS27_CIOIN H2XS74_CIOIN H2XS74_CIOIN H2XT32_CIOIN H2XT32_CIOIN H2XUL2_CIOIN H2XUL2_CIOIN ENSCINP00000033553 ENSCINP00000033553 LOC104266883 LOC104266883 H2XWT8_CIOIN H2XWT8_CIOIN H2XWW8_CIOIN H2XWW8_CIOIN hlx hlx H2Y066_CIOIN H2Y066_CIOIN H2Y0B1_CIOIN H2Y0B1_CIOIN H2Y0C2_CIOIN H2Y0C2_CIOIN H2Y0R6_CIOIN H2Y0R6_CIOIN H2Y0V6_CIOIN H2Y0V6_CIOIN H2Y1D3_CIOIN H2Y1D3_CIOIN H2Y1K9_CIOIN H2Y1K9_CIOIN H2Y1Q5_CIOIN H2Y1Q5_CIOIN H2Y1S8_CIOIN H2Y1S8_CIOIN LOC100182428 LOC100182428 H2Y255_CIOIN H2Y255_CIOIN H2Y2G5_CIOIN H2Y2G5_CIOIN H2Y2U9_CIOIN H2Y2U9_CIOIN H2Y2V4_CIOIN H2Y2V4_CIOIN H2Y2W2_CIOIN H2Y2W2_CIOIN smad2/3a smad2/3a LOC100185957 LOC100185957 H2Y3S1_CIOIN H2Y3S1_CIOIN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
H2XRP4_CIOINUncharacterized protein. (126 aa)
Tgfbr-iibReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (567 aa)
tgfbr-iiaSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (622 aa)
LOC100179981Uncharacterized protein. (229 aa)
cdc42Uncharacterized protein. (95 aa)
LOC100176290Uncharacterized protein LOC100176290 isoform X4. (787 aa)
LOC100187261Protein FAM210B, mitochondrial isoform X1. (206 aa)
LOC100176958Golgi-associated plant pathogenesis-related protein 1 isoform X1; Belongs to the CRISP family. (192 aa)
soxESoxE protein. (808 aa)
Zf(c2h2)-69Uncharacterized protein. (940 aa)
Sir2-dDeacetylase sirtuin-type domain-containing protein. (91 aa)
SmoothenedUncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (441 aa)
F6VK85_CIOINUncharacterized protein; Belongs to the PI3/PI4-kinase family. (754 aa)
LOC100184368Integrin-linked protein kinase. (447 aa)
tgfbr-iaReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (423 aa)
LOC100178597Myeloid-associated differentiation marker-like protein 2 isoform X1. (285 aa)
p53/p73-aTranscription factor protein. (489 aa)
F6WSD2_CIOINBSD domain-containing protein. (400 aa)
F6W6K0_CIOINUncharacterized protein. (534 aa)
LOC778720Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (510 aa)
P53/p73-bUncharacterized protein. (419 aa)
F6W2W8_CIOINRunt domain-containing protein. (432 aa)
F6YDG1_CIOINCULLIN_2 domain-containing protein; Belongs to the cullin family. (586 aa)
F6SCE7_CIOINUncharacterized protein. (361 aa)
F6PPJ1_CIOINProtein kinase C. (582 aa)
F7BBL3_CIOINUncharacterized protein. (310 aa)
F7BBJ6_CIOINWD_REPEATS_REGION domain-containing protein. (473 aa)
LOC100182260Aspartoacylase-like. (309 aa)
LOC100178220Zinc finger C4H2 domain-containing protein-like. (227 aa)
F6WMR0_CIOINFatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (238 aa)
smyd1Uncharacterized protein. (474 aa)
F7BHR3_CIOINUncharacterized protein. (857 aa)
LOC100178665Fatty acid hydroxylase domain-containing protein 2-like; Belongs to the sterol desaturase family. (301 aa)
F6ZM08_CIOINUncharacterized protein. (782 aa)
F6RYG5_CIOINRRM domain-containing protein. (189 aa)
neurogeninTranscription factor protein isoform X1. (409 aa)
F7B6D7_CIOINCOMM domain-containing protein. (224 aa)
otpTranscription factor protein isoform X1. (492 aa)
LOC100179870Peptidase_M24 domain-containing protein. (394 aa)
LOC100181085Monocyte to macrophage differentiation factor. (314 aa)
Dll-aHomeobox domain-containing protein. (453 aa)
LOC100181221Integumentary mucin C.1-like. (367 aa)
zf(c2h2)-102ATP-dependent DNA helicase II subunit 2; Single-stranded DNA-dependent ATP-dependent helicase. (706 aa)
NumbPID domain-containing protein. (430 aa)
XbpaBZIP domain-containing protein. (309 aa)
LOC100178307Fatty acid hydroxylase domain-containing protein 2; Belongs to the sterol desaturase family. (332 aa)
sfrp2Secreted frizzled-related protein isoform X1. (293 aa)
LOC100181891Uncharacterized protein. (373 aa)
smad4Mothers against decapentaplegic homolog. (527 aa)
F6ZQY6_CIOINPoly [ADP-ribose] polymerase. (537 aa)
tgfbr-ibReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (531 aa)
LOC100185251-2Zinc finger protein. (339 aa)
F6ZG18_CIOINFERM domain-containing protein. (589 aa)
F6ZFJ9_CIOINAlpha-type protein kinase domain-containing protein. (678 aa)
F6SDP7_CIOINEGF-like domain-containing protein. (628 aa)
F7BL69_CIOINWD_REPEATS_REGION domain-containing protein. (598 aa)
LOC100178575Mothers against decapentaplegic homolog. (426 aa)
F6YC82_CIOINSARAH domain-containing protein. (138 aa)
F6PSM8_CIOINUncharacterized protein. (690 aa)
F6RS66_CIOINProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (462 aa)
F6RJA6_CIOINUncharacterized protein. (322 aa)
F6RI21_CIOINUncharacterized protein. (355 aa)
LOC100187100Lysine-specific histone demethylase 1A. (705 aa)
Zf(c2h2)-33Uncharacterized protein. (999 aa)
Cibeta-cateninUncharacterized protein. (497 aa)
myodTranscription factor protein isoform X1. (590 aa)
F6UMA7_CIOINPID domain-containing protein. (458 aa)
xbpdTranscription factor protein isoform X1. (366 aa)
F6YIR3_CIOINJmjC domain-containing protein. (332 aa)
LOC100185086Uncharacterized protein. (126 aa)
F6VXC2_CIOINProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (262 aa)
F6X4F9_CIOINUncharacterized protein. (262 aa)
F6THB4_CIOINUncharacterized protein. (181 aa)
soxCHMG transcription factor SoxC isoform X1. (525 aa)
F6QTW3_CIOINTyrosine-protein kinase. (626 aa)
LOC100183284SKIP_SNW domain-containing protein. (534 aa)
Tgfbeta2TGF_BETA_2 domain-containing protein. (435 aa)
F6UDR5_CIOINUncharacterized protein. (723 aa)
F6T283_CIOINUncharacterized protein. (454 aa)
Ci-NetTranscription factor protein. (205 aa)
snailUncharacterized protein. (584 aa)
F6R6C4_CIOINUncharacterized protein. (802 aa)
cbfbCore-binding factor, b subunit isoform X1. (181 aa)
rngiCaprin-1_dimer domain-containing protein. (703 aa)
Fgf8/17/18Uncharacterized protein; Belongs to the heparin-binding growth factors family. (414 aa)
e12/e47Transcription factor protein. (641 aa)
F6UX10_CIOINDNA_LIGASE_A3 domain-containing protein; Belongs to the ATP-dependent DNA ligase family. (655 aa)
F7ABT2_CIOINSema domain-containing protein. (1549 aa)
xbpbTranscription factor protein. (238 aa)
tgfbeta-na4TGF_BETA_2 domain-containing protein. (442 aa)
F6TBG7_CIOINUncharacterized protein. (1221 aa)
Q4H307_CIOINProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (249 aa)
F6WM20_CIOINUncharacterized protein. (404 aa)
F6YJE0_CIOINUncharacterized protein. (772 aa)
F6VYF2_CIOINUncharacterized protein. (797 aa)
LOC100179144SUN domain-containing ossification factor-like isoform X1. (770 aa)
LOC100178690Fas apoptotic inhibitory molecule 1-like. (181 aa)
F6UIG7_CIOINCARM1 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (461 aa)
F7AVR1_CIOINHomeobox domain-containing protein. (418 aa)
F7AAV2_CIOINEGF-like domain-containing protein. (618 aa)
LOC100176678PITH domain-containing protein 1. (209 aa)
F6WQL4_CIOINBZIP domain-containing protein. (312 aa)
F6RLL0_CIOINUncharacterized protein. (322 aa)
wnt3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (304 aa)
F6V7C2_CIOINProtein kinase domain-containing protein. (521 aa)
F6TTH0_CIOINUncharacterized protein. (426 aa)
F6YXX9_CIOINUncharacterized protein. (883 aa)
F6V476_CIOINUncharacterized protein. (282 aa)
F6SFW9_CIOINFork-head domain-containing protein. (470 aa)
XbpcBZIP domain-containing protein. (437 aa)
F6YWM5_CIOINBHLH domain-containing protein. (96 aa)
F7B221_CIOINLIM domain-containing protein. (326 aa)
F6PQC6_CIOINClaudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (217 aa)
F6TZA7_CIOINUncharacterized protein. (273 aa)
F7AFQ9_CIOINUncharacterized protein. (482 aa)
Klf2Uncharacterized protein. (610 aa)
F6SYE0_CIOINProtein kinase domain-containing protein. (216 aa)
F6YSG2_CIOINRWD domain-containing protein. (260 aa)
F6U7G3_CIOINHMG box domain-containing protein. (364 aa)
F6SLD6_CIOINDeacetylase sirtuin-type domain-containing protein. (737 aa)
LOC779004Transcription factor protein. (553 aa)
F7AK80_CIOINUncharacterized protein. (382 aa)
F7AIB9_CIOINUncharacterized protein. (271 aa)
H2XKM4_CIOINIPT/TIG domain-containing protein. (187 aa)
H2XM17_CIOINFAT domain-containing protein. (187 aa)
Q1RPY5_CIOINZinc finger protein. (579 aa)
LOC100181388Uncharacterized protein LOC100181388. (184 aa)
Bmp2/4TGFb_propeptide domain-containing protein. (376 aa)
H2XN97_CIOINUncharacterized protein. (200 aa)
H2XPA3_CIOINRas-GEF domain-containing protein. (451 aa)
H2XPL3_CIOINUncharacterized protein. (434 aa)
H2XQ71_CIOING_PROTEIN_RECEP_F1_2 domain-containing protein. (159 aa)
H2XRZ5_CIOINUncharacterized protein. (217 aa)
srfTranscription factor protein. (335 aa)
H2XS27_CIOINUncharacterized protein. (75 aa)
H2XS74_CIOINUncharacterized protein. (301 aa)
H2XT32_CIOINUncharacterized protein. (127 aa)
H2XUL2_CIOINUncharacterized protein. (299 aa)
ENSCINP00000033553annotation not available (74 aa)
LOC104266883Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] (239 aa)
H2XWT8_CIOINUncharacterized protein. (206 aa)
H2XWW8_CIOINOlfactomedin-like domain-containing protein. (121 aa)
hlxHomeobox domain-containing protein. (554 aa)
H2Y066_CIOINUncharacterized protein. (361 aa)
H2Y0B1_CIOINHIT-type domain-containing protein. (167 aa)
H2Y0C2_CIOINUncharacterized protein. (138 aa)
H2Y0R6_CIOINMediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (227 aa)
H2Y0V6_CIOINUncharacterized protein. (204 aa)
H2Y1D3_CIOINUncharacterized protein. (132 aa)
H2Y1K9_CIOINUncharacterized protein. (674 aa)
H2Y1Q5_CIOINSAP domain-containing protein. (353 aa)
H2Y1S8_CIOINCASPASE_P20 domain-containing protein; Belongs to the peptidase C14A family. (162 aa)
LOC100182428NF-kappa-B inhibitor zeta-like isoform X1. (649 aa)
H2Y255_CIOINCTCK domain-containing protein. (191 aa)
H2Y2G5_CIOINMediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (160 aa)
H2Y2U9_CIOINUncharacterized protein. (884 aa)
H2Y2V4_CIOINProtein kinase domain-containing protein. (209 aa)
H2Y2W2_CIOINSSD domain-containing protein. (1179 aa)
smad2/3aMothers against decapentaplegic homolog. (446 aa)
LOC100185957Mucosa-associated lymphoid tissue lymphoma translocation protein 1-like isoform X1. (624 aa)
H2Y3S1_CIOINUncharacterized protein. (316 aa)
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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