(16 nodes) Ceramide catabolic process network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100182270	Alpha-galactosidase. (417 aa)
	H2XP03_CIOIN	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (110 aa)
	LOC100178882	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (167 aa)
	F6Q8G4_CIOIN	Uncharacterized protein; Belongs to the acid ceramidase family. (392 aa)
	F6RCR0_CIOIN	Neutral ceramidase. (771 aa)
	F6QEE6_CIOIN	Neutral ceramidase. (748 aa)
	F6U9S8_CIOIN	Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide. (785 aa)
	LOC100187142	Beta-hexosaminidase. (535 aa)
	LOC100178428	Beta-hexosaminidase. (538 aa)
	F6UTT2_CIOIN	Neutral ceramidase. (688 aa)
	F7AA01_CIOIN	Glucosylceramidase. (561 aa)
	F6Y921_CIOIN	Glyco_hydro_59M domain-containing protein. (677 aa)
	F6TJR3_CIOIN	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (242 aa)
	F7AV79_CIOIN	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (228 aa)
	H2XJY8_CIOIN	Glucosylceramidase. (518 aa)
	H2XMX0_CIOIN	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (143 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6Q8G4_CIOIN	F6TJR3_CIOIN	ENSCINP00000004990	ENSCINP00000021779	Uncharacterized protein; Belongs to the acid ceramidase family.	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.	0.920
F6Q8G4_CIOIN	F6U9S8_CIOIN	ENSCINP00000004990	ENSCINP00000007158	Uncharacterized protein; Belongs to the acid ceramidase family.	Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide.	0.492
F6Q8G4_CIOIN	F6UTT2_CIOIN	ENSCINP00000004990	ENSCINP00000011274	Uncharacterized protein; Belongs to the acid ceramidase family.	Neutral ceramidase.	0.925
F6Q8G4_CIOIN	F6Y921_CIOIN	ENSCINP00000004990	ENSCINP00000019330	Uncharacterized protein; Belongs to the acid ceramidase family.	Glyco_hydro_59M domain-containing protein.	0.949
F6Q8G4_CIOIN	F7AA01_CIOIN	ENSCINP00000004990	ENSCINP00000016220	Uncharacterized protein; Belongs to the acid ceramidase family.	Glucosylceramidase.	0.922
F6Q8G4_CIOIN	F7AV79_CIOIN	ENSCINP00000004990	ENSCINP00000023348	Uncharacterized protein; Belongs to the acid ceramidase family.	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.	0.920
F6Q8G4_CIOIN	H2XJY8_CIOIN	ENSCINP00000004990	ENSCINP00000029970	Uncharacterized protein; Belongs to the acid ceramidase family.	Glucosylceramidase.	0.922
F6Q8G4_CIOIN	H2XMX0_CIOIN	ENSCINP00000004990	ENSCINP00000031003	Uncharacterized protein; Belongs to the acid ceramidase family.	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.	0.917
F6Q8G4_CIOIN	H2XP03_CIOIN	ENSCINP00000004990	ENSCINP00000031386	Uncharacterized protein; Belongs to the acid ceramidase family.	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.	0.947
F6Q8G4_CIOIN	LOC100178882	ENSCINP00000004990	ENSCINP00000000095	Uncharacterized protein; Belongs to the acid ceramidase family.	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.	0.920
F6TJR3_CIOIN	F6Q8G4_CIOIN	ENSCINP00000021779	ENSCINP00000004990	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.	Uncharacterized protein; Belongs to the acid ceramidase family.	0.920
F6TJR3_CIOIN	F6UTT2_CIOIN	ENSCINP00000021779	ENSCINP00000011274	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.	Neutral ceramidase.	0.917
F6TJR3_CIOIN	F6Y921_CIOIN	ENSCINP00000021779	ENSCINP00000019330	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.	Glyco_hydro_59M domain-containing protein.	0.907
F6TJR3_CIOIN	F7AA01_CIOIN	ENSCINP00000021779	ENSCINP00000016220	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.	Glucosylceramidase.	0.901
F6TJR3_CIOIN	F7AV79_CIOIN	ENSCINP00000021779	ENSCINP00000023348	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.	0.903
F6TJR3_CIOIN	H2XJY8_CIOIN	ENSCINP00000021779	ENSCINP00000029970	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.	Glucosylceramidase.	0.901
F6TJR3_CIOIN	H2XMX0_CIOIN	ENSCINP00000021779	ENSCINP00000031003	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.	0.906
F6TJR3_CIOIN	LOC100178882	ENSCINP00000021779	ENSCINP00000000095	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.	0.904
F6U9S8_CIOIN	F6Q8G4_CIOIN	ENSCINP00000007158	ENSCINP00000004990	Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide.	Uncharacterized protein; Belongs to the acid ceramidase family.	0.492
F6UTT2_CIOIN	F6Q8G4_CIOIN	ENSCINP00000011274	ENSCINP00000004990	Neutral ceramidase.	Uncharacterized protein; Belongs to the acid ceramidase family.	0.925