(29 nodes) Negative regulation of epithelial cell proliferation network (Ciona intestinalis)

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second shell of interactors

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Known Interactions

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Predicted Interactions

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Your Input:
	Tgfbeta2	TGF_BETA_2 domain-containing protein. (435 aa)
	LOC100183377	Vasohibin-1-like isoform X2. (319 aa)
	Ipf1	Homeobox domain-containing protein. (411 aa)
	LOC100177697	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (236 aa)
	F6UJF1_CIOIN	UDENN FLCN/SMCR8-type domain-containing protein. (561 aa)
	F7APX0_CIOIN	Uncharacterized protein. (1090 aa)
	F6TLB6_CIOIN	Uncharacterized protein. (891 aa)
	sfrp2	Secreted frizzled-related protein isoform X1. (293 aa)
	F6YC82_CIOIN	SARAH domain-containing protein. (138 aa)
	F6RS66_CIOIN	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (462 aa)
	ciatpsyna	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (554 aa)
	F6RR11_CIOIN	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (422 aa)
	F6UMA7_CIOIN	PID domain-containing protein. (458 aa)
	F6X0V6_CIOIN	Uncharacterized protein. (426 aa)
	Ci-Net	Transcription factor protein. (205 aa)
	LOC100184954	Uncharacterized protein. (760 aa)
	LOC100176974	Uncharacterized protein. (588 aa)
	ppar	Nuclear receptor. (644 aa)
	F7B221_CIOIN	LIM domain-containing protein. (326 aa)
	F6XLS2_CIOIN	Uncharacterized protein. (745 aa)
	F6W3W9_CIOIN	Uncharacterized protein. (758 aa)
	F6T2G1_CIOIN	Uncharacterized protein. (298 aa)
	LOC100178517	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (142 aa)
	H2XNY4_CIOIN	EAF domain-containing protein. (241 aa)
	LOC100185578	Aminoacyl tRNA synthase complex-interacting multifunctional protein 1. (297 aa)
	H2XUU5_CIOIN	Uncharacterized protein. (532 aa)
	LOC100183150	WD repeat-containing protein 13-like. (463 aa)
	H2Y0R6_CIOIN	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (227 aa)
	H2Y2G5_CIOIN	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (160 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6RR11_CIOIN	H2Y0R6_CIOIN	ENSCINP00000013130	ENSCINP00000035500	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.680
F6RR11_CIOIN	H2Y2G5_CIOIN	ENSCINP00000013130	ENSCINP00000036100	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.680
F6RR11_CIOIN	ciatpsyna	ENSCINP00000013130	ENSCINP00000013107	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.543
F6T2G1_CIOIN	F6TLB6_CIOIN	ENSCINP00000029547	ENSCINP00000007196	Uncharacterized protein.	Uncharacterized protein.	0.950
F6T2G1_CIOIN	F6W3W9_CIOIN	ENSCINP00000029547	ENSCINP00000028344	Uncharacterized protein.	Uncharacterized protein.	0.946
F6TLB6_CIOIN	F6T2G1_CIOIN	ENSCINP00000007196	ENSCINP00000029547	Uncharacterized protein.	Uncharacterized protein.	0.950
F6TLB6_CIOIN	F6W3W9_CIOIN	ENSCINP00000007196	ENSCINP00000028344	Uncharacterized protein.	Uncharacterized protein.	0.949
F6W3W9_CIOIN	F6T2G1_CIOIN	ENSCINP00000028344	ENSCINP00000029547	Uncharacterized protein.	Uncharacterized protein.	0.946
F6W3W9_CIOIN	F6TLB6_CIOIN	ENSCINP00000028344	ENSCINP00000007196	Uncharacterized protein.	Uncharacterized protein.	0.949
F6X0V6_CIOIN	LOC100176974	ENSCINP00000017470	ENSCINP00000018086	Uncharacterized protein.	Uncharacterized protein.	0.983
F6X0V6_CIOIN	LOC100184954	ENSCINP00000017470	ENSCINP00000018073	Uncharacterized protein.	Uncharacterized protein.	0.983
H2XNY4_CIOIN	H2XUU5_CIOIN	ENSCINP00000031367	ENSCINP00000033429	EAF domain-containing protein.	Uncharacterized protein.	0.540
H2XUU5_CIOIN	H2XNY4_CIOIN	ENSCINP00000033429	ENSCINP00000031367	Uncharacterized protein.	EAF domain-containing protein.	0.540
H2Y0R6_CIOIN	F6RR11_CIOIN	ENSCINP00000035500	ENSCINP00000013130	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.680
H2Y0R6_CIOIN	H2Y2G5_CIOIN	ENSCINP00000035500	ENSCINP00000036100	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.633
H2Y0R6_CIOIN	ciatpsyna	ENSCINP00000035500	ENSCINP00000013107	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.680
H2Y0R6_CIOIN	ppar	ENSCINP00000035500	ENSCINP00000024308	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Nuclear receptor.	0.449
H2Y2G5_CIOIN	F6RR11_CIOIN	ENSCINP00000036100	ENSCINP00000013130	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.680
H2Y2G5_CIOIN	H2Y0R6_CIOIN	ENSCINP00000036100	ENSCINP00000035500	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.633
H2Y2G5_CIOIN	ciatpsyna	ENSCINP00000036100	ENSCINP00000013107	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.680