(55 nodes) Positive regulation of secretion network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Xbpc	BZIP domain-containing protein. (437 aa)
	F6TF85_CIOIN	Apt1 domain-containing protein. (574 aa)
	F6TF93_CIOIN	Uncharacterized protein. (311 aa)
	Ipf1	Homeobox domain-containing protein. (411 aa)
	Sir2-d	Deacetylase sirtuin-type domain-containing protein. (91 aa)
	F6YIB7_CIOIN	DAGKc domain-containing protein. (608 aa)
	LOC100180419	Golgi phosphoprotein 3-like. (291 aa)
	F6S566_CIOIN	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (345 aa)
	F6Z5N9_CIOIN	Rhomboid domain-containing protein. (213 aa)
	Ci-FXR	Nuclear receptor. (294 aa)
	F6TT57_CIOIN	Uncharacterized protein. (762 aa)
	LOC100179839	Sorting nexin-4-like. (441 aa)
	LOC104266814	ADP-ribosylation factor 6-like; Belongs to the small GTPase superfamily. Arf family. (174 aa)
	F6PMK8_CIOIN	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (710 aa)
	F7B9A9_CIOIN	Uncharacterized protein. (1197 aa)
	F7AQ24_CIOIN	Uncharacterized protein. (323 aa)
	Xbpa	BZIP domain-containing protein. (309 aa)
	F6UTA8_CIOIN	Uncharacterized protein. (856 aa)
	smad4	Mothers against decapentaplegic homolog. (527 aa)
	zf(fyve)-11	Uncharacterized protein. (717 aa)
	LOC100180144	Vacuolar protein sorting-associated protein 4B-like; Belongs to the AAA ATPase family. (438 aa)
	LOC100181289	Cyclin-dependent-like kinase 5; Belongs to the protein kinase superfamily. (292 aa)
	F6UMA7_CIOIN	PID domain-containing protein. (458 aa)
	xbpd	Transcription factor protein isoform X1. (366 aa)
	Tgfbeta2	TGF_BETA_2 domain-containing protein. (435 aa)
	LOC100187068	Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (123 aa)
	F6PHZ4_CIOIN	Uncharacterized protein. (266 aa)
	xbpb	Transcription factor protein. (238 aa)
	LOC100175291	Uncharacterized protein LOC100175291. (180 aa)
	F6W0C3_CIOIN	Uncharacterized protein. (683 aa)
	F7BDH1_CIOIN	BRO1 domain-containing protein. (902 aa)
	F6U1C4_CIOIN	Uncharacterized protein. (318 aa)
	F6YCG7_CIOIN	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1086 aa)
	F6ZGS0_CIOIN	TMF_TATA_bd domain-containing protein. (317 aa)
	H2Y1U8_CIOIN	Uncharacterized protein. (232 aa)
	LOC100185836	ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (196 aa)
	H2XWT7_CIOIN	Fmp27_GFWDK domain-containing protein. (247 aa)
	H2XWD4_CIOIN	Uncharacterized protein. (174 aa)
	H2XWC1_CIOIN	GOLD domain-containing protein. (205 aa)
	H2XVL2_CIOIN	Uncharacterized protein. (236 aa)
	H2XUP2_CIOIN	V-SNARE coiled-coil homology domain-containing protein. (84 aa)
	atg5	Autophagy protein 5; Involved in autophagic vesicle formation. (268 aa)
	H2XTV9_CIOIN	Uncharacterized protein. (362 aa)
	LOC100185578	Aminoacyl tRNA synthase complex-interacting multifunctional protein 1. (297 aa)
	LOC100176146	Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (125 aa)
	LOC104265386	Uncharacterized protein. (402 aa)
	LOC100182370	Cytochrome b-245 light chain isoform X1. (175 aa)
	H2XNH1_CIOIN	Uncharacterized protein. (191 aa)
	H2XLA2_CIOIN	Uncharacterized protein. (206 aa)
	F6QC67_CIOIN	Uncharacterized protein. (215 aa)
	F6SWJ9_CIOIN	Uncharacterized protein. (130 aa)
	F6UMZ6_CIOIN	Uncharacterized protein. (360 aa)
	F6UNA9_CIOIN	Sec3_C domain-containing protein. (314 aa)
	F6QP81_CIOIN	Uncharacterized protein. (135 aa)
	F6XND0_CIOIN	Uncharacterized protein. (233 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6PHZ4_CIOIN	F6UMA7_CIOIN	ENSCINP00000020279	ENSCINP00000015165	Uncharacterized protein.	PID domain-containing protein.	0.540
F6PHZ4_CIOIN	F7AQ24_CIOIN	ENSCINP00000020279	ENSCINP00000010164	Uncharacterized protein.	Uncharacterized protein.	0.912
F6PHZ4_CIOIN	F7BDH1_CIOIN	ENSCINP00000020279	ENSCINP00000023330	Uncharacterized protein.	BRO1 domain-containing protein.	0.619
F6PHZ4_CIOIN	H2XUP2_CIOIN	ENSCINP00000020279	ENSCINP00000033376	Uncharacterized protein.	V-SNARE coiled-coil homology domain-containing protein.	0.414
F6PHZ4_CIOIN	LOC104265386	ENSCINP00000020279	ENSCINP00000031475	Uncharacterized protein.	Uncharacterized protein.	0.959
F6PHZ4_CIOIN	zf(fyve)-11	ENSCINP00000020279	ENSCINP00000013389	Uncharacterized protein.	Uncharacterized protein.	0.999
F6PMK8_CIOIN	F6UMA7_CIOIN	ENSCINP00000009846	ENSCINP00000015165	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	PID domain-containing protein.	0.410
F6PMK8_CIOIN	H2XUP2_CIOIN	ENSCINP00000009846	ENSCINP00000033376	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	V-SNARE coiled-coil homology domain-containing protein.	0.446
F6PMK8_CIOIN	LOC100179839	ENSCINP00000009846	ENSCINP00000009207	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Sorting nexin-4-like.	0.420
F6PMK8_CIOIN	atg5	ENSCINP00000009846	ENSCINP00000033358	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.527
F6PMK8_CIOIN	zf(fyve)-11	ENSCINP00000009846	ENSCINP00000013389	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Uncharacterized protein.	0.417
F6QC67_CIOIN	H2XTV9_CIOIN	ENSCINP00000028919	ENSCINP00000033093	Uncharacterized protein.	Uncharacterized protein.	0.435
F6SWJ9_CIOIN	F6XND0_CIOIN	ENSCINP00000026601	ENSCINP00000024885	Uncharacterized protein.	Uncharacterized protein.	0.417
F6SWJ9_CIOIN	H2Y1U8_CIOIN	ENSCINP00000026601	ENSCINP00000035883	Uncharacterized protein.	Uncharacterized protein.	0.417
F6SWJ9_CIOIN	LOC104265386	ENSCINP00000026601	ENSCINP00000031475	Uncharacterized protein.	Uncharacterized protein.	0.509
F6SWJ9_CIOIN	atg5	ENSCINP00000026601	ENSCINP00000033358	Uncharacterized protein.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.536
F6SWJ9_CIOIN	zf(fyve)-11	ENSCINP00000026601	ENSCINP00000013389	Uncharacterized protein.	Uncharacterized protein.	0.474
F6TF85_CIOIN	F6TF93_CIOIN	ENSCINP00000023572	ENSCINP00000023571	Apt1 domain-containing protein.	Uncharacterized protein.	0.401
F6TF85_CIOIN	H2XNH1_CIOIN	ENSCINP00000023572	ENSCINP00000031204	Apt1 domain-containing protein.	Uncharacterized protein.	0.684
F6TF85_CIOIN	H2XVL2_CIOIN	ENSCINP00000023572	ENSCINP00000033696	Apt1 domain-containing protein.	Uncharacterized protein.	0.943