STRINGSTRING
hlx hlx LOC101243096 LOC101243096 LOC100178228 LOC100178228 H2XZ57_CIOIN H2XZ57_CIOIN H2Y015_CIOIN H2Y015_CIOIN LOC101242365 LOC101242365 H2Y1D3_CIOIN H2Y1D3_CIOIN H2Y1D7_CIOIN H2Y1D7_CIOIN H2Y1F5_CIOIN H2Y1F5_CIOIN H2Y1T8_CIOIN H2Y1T8_CIOIN H2Y1U4_CIOIN H2Y1U4_CIOIN LOC100179332 LOC100179332 H2Y2K4_CIOIN H2Y2K4_CIOIN LOC100179981 LOC100179981 LOC100183377 LOC100183377 LOC100181983 LOC100181983 F6VNT1_CIOIN F6VNT1_CIOIN Smoothened Smoothened F6Z442_CIOIN F6Z442_CIOIN F6UJF1_CIOIN F6UJF1_CIOIN mT mT gsk gsk p53/p73-a p53/p73-a P53/p73-b P53/p73-b LOC100182351 LOC100182351 Rev-erb Rev-erb F6QD80_CIOIN F6QD80_CIOIN LOC100187015 LOC100187015 F6XN00_CIOIN F6XN00_CIOIN F6PHN1_CIOIN F6PHN1_CIOIN F6R6F3_CIOIN F6R6F3_CIOIN nachr-3 nachr-3 F6TBE2_CIOIN F6TBE2_CIOIN F7APX0_CIOIN F7APX0_CIOIN F6TLB6_CIOIN F6TLB6_CIOIN F7BHN2_CIOIN F7BHN2_CIOIN Ci-FXR Ci-FXR LOC100181489 LOC100181489 F6XIK7_CIOIN F6XIK7_CIOIN LOC100180825 LOC100180825 LOC100184817 LOC100184817 F6ZT56_CIOIN F6ZT56_CIOIN F7B5N7_CIOIN F7B5N7_CIOIN LOC100184905 LOC100184905 Dll-a Dll-a LOC100181706 LOC100181706 F6PRY2_CIOIN F6PRY2_CIOIN F6R946_CIOIN F6R946_CIOIN F7AQ24_CIOIN F7AQ24_CIOIN L7N0S2_CIOIN L7N0S2_CIOIN myc myc sfrp2 sfrp2 F6YQ60_CIOIN F6YQ60_CIOIN smad4 smad4 Ephrin-a Ephrin-a F6RGF8_CIOIN F6RGF8_CIOIN LOC100185251-2 LOC100185251-2 F6WF44_CIOIN F6WF44_CIOIN F6ZG18_CIOIN F6ZG18_CIOIN F6YC82_CIOIN F6YC82_CIOIN F6PSM8_CIOIN F6PSM8_CIOIN F6RS66_CIOIN F6RS66_CIOIN F6QQZ3_CIOIN F6QQZ3_CIOIN zf(fyve)-11 zf(fyve)-11 F6QP05_CIOIN F6QP05_CIOIN LOC100181289 LOC100181289 F6TZD2_CIOIN F6TZD2_CIOIN F6YAC3_CIOIN F6YAC3_CIOIN LOC100187208 LOC100187208 F6YRI1_CIOIN F6YRI1_CIOIN F6Y836_CIOIN F6Y836_CIOIN F6UL80_CIOIN F6UL80_CIOIN LOC104266675 LOC104266675 LOC100185679 LOC100185679 F7AP04_CIOIN F7AP04_CIOIN mox mox F6X5U2_CIOIN F6X5U2_CIOIN LOC619278 LOC619278 F6T7M7_CIOIN F6T7M7_CIOIN F6X4F9_CIOIN F6X4F9_CIOIN F7AA01_CIOIN F7AA01_CIOIN F7A9X0_CIOIN F7A9X0_CIOIN LOC100178394 LOC100178394 zf(c2h2)-129 zf(c2h2)-129 F6XRP8_CIOIN F6XRP8_CIOIN Tgfbeta2 Tgfbeta2 F7BJL5_CIOIN F7BJL5_CIOIN F6PKT6_CIOIN F6PKT6_CIOIN smad6/7 smad6/7 F6R6J0_CIOIN F6R6J0_CIOIN LOC100186815 LOC100186815 LOC100177957 LOC100177957 cbfb cbfb F6ZDN3_CIOIN F6ZDN3_CIOIN F7ACP0_CIOIN F7ACP0_CIOIN F6ZUG2_CIOIN F6ZUG2_CIOIN F7AWH6_CIOIN F7AWH6_CIOIN F7AVR1_CIOIN F7AVR1_CIOIN F6Q0D8_CIOIN F6Q0D8_CIOIN F6PZR6_CIOIN F6PZR6_CIOIN F6PSZ6_CIOIN F6PSZ6_CIOIN F6PSX9_CIOIN F6PSX9_CIOIN F6RH73_CIOIN F6RH73_CIOIN wnt3 wnt3 F6TTH0_CIOIN F6TTH0_CIOIN F6ZHF5_CIOIN F6ZHF5_CIOIN F6V5K2_CIOIN F6V5K2_CIOIN F6V4V0_CIOIN F6V4V0_CIOIN F7BLL2_CIOIN F7BLL2_CIOIN F6YXM6_CIOIN F6YXM6_CIOIN F6YWM5_CIOIN F6YWM5_CIOIN LOC778708 LOC778708 F6VS24_CIOIN F6VS24_CIOIN F7BKY1_CIOIN F7BKY1_CIOIN F7BKM3_CIOIN F7BKM3_CIOIN LOC101242476 LOC101242476 F6QGN1_CIOIN F6QGN1_CIOIN F6PQC6_CIOIN F6PQC6_CIOIN LOC100184123 LOC100184123 F6TDS0_CIOIN F6TDS0_CIOIN F6TCY4_CIOIN F6TCY4_CIOIN LOC100187147 LOC100187147 LOC100185445 LOC100185445 LOC100183082 LOC100183082 F6ZXH0_CIOIN F6ZXH0_CIOIN F6ZX31_CIOIN F6ZX31_CIOIN F6XLS2_CIOIN F6XLS2_CIOIN LOC100178267 LOC100178267 F6Y6P2_CIOIN F6Y6P2_CIOIN F6U7K8_CIOIN F6U7K8_CIOIN F6U7G3_CIOIN F6U7G3_CIOIN LOC100178900 LOC100178900 LOC779004 LOC779004 F6W3W9_CIOIN F6W3W9_CIOIN F6VHE0_CIOIN F6VHE0_CIOIN F6YNB1_CIOIN F6YNB1_CIOIN F7AIB9_CIOIN F7AIB9_CIOIN F6T2G1_CIOIN F6T2G1_CIOIN H2XJG5_CIOIN H2XJG5_CIOIN LOC100180326 LOC100180326 H2XJY8_CIOIN H2XJY8_CIOIN H2XMV3_CIOIN H2XMV3_CIOIN Bmp2/4 Bmp2/4 H2XN97_CIOIN H2XN97_CIOIN dynlt1 dynlt1 H2XNX7_CIOIN H2XNX7_CIOIN H2XNY4_CIOIN H2XNY4_CIOIN H2XPA3_CIOIN H2XPA3_CIOIN H2XPV6_CIOIN H2XPV6_CIOIN Q1RL63_CIOIN Q1RL63_CIOIN H2XQ88_CIOIN H2XQ88_CIOIN H2XR40_CIOIN H2XR40_CIOIN srf srf H2XS27_CIOIN H2XS27_CIOIN LOC100187478 LOC100187478 H2XU53_CIOIN H2XU53_CIOIN LOC100183239 LOC100183239 H2XUF2_CIOIN H2XUF2_CIOIN H2XUI8_CIOIN H2XUI8_CIOIN H2XUK8_CIOIN H2XUK8_CIOIN atg5 atg5 LOC100182647 LOC100182647 H2XV03_CIOIN H2XV03_CIOIN LOC100179235 LOC100179235 H2XVX2_CIOIN H2XVX2_CIOIN H2XXS3_CIOIN H2XXS3_CIOIN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
hlxHomeobox domain-containing protein. (554 aa)
LOC101243096Trefoil factor 2-like. (119 aa)
LOC100178228ANF_receptor domain-containing protein. (426 aa)
H2XZ57_CIOINUncharacterized protein. (229 aa)
H2Y015_CIOINEGF-like domain-containing protein. (182 aa)
LOC101242365Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (98 aa)
H2Y1D3_CIOINUncharacterized protein. (132 aa)
H2Y1D7_CIOINNAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX; Belongs to the NnrE/AIBP family. (281 aa)
H2Y1F5_CIOINFibrinogen C-terminal domain-containing protein. (283 aa)
H2Y1T8_CIOING_PROTEIN_RECEP_F1_2 domain-containing protein. (149 aa)
H2Y1U4_CIOINTIR domain-containing protein. (268 aa)
LOC100179332semaphorin-4G-like isoform X3; Belongs to the semaphorin family. (793 aa)
H2Y2K4_CIOIN3-hydroxy-3-methylglutaryl coenzyme A reductase. (807 aa)
LOC100179981Uncharacterized protein. (229 aa)
LOC100183377Vasohibin-1-like isoform X2. (319 aa)
LOC100181983PRKC apoptosis WT1 regulator protein-like. (304 aa)
F6VNT1_CIOINUncharacterized protein. (229 aa)
SmoothenedUncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (441 aa)
F6Z442_CIOINFibrinogen C-terminal domain-containing protein. (331 aa)
F6UJF1_CIOINUDENN FLCN/SMCR8-type domain-containing protein. (561 aa)
mTUncharacterized protein. (812 aa)
gskGlycogen synthase kinase Alpha/beta. (407 aa)
p53/p73-aTranscription factor protein. (489 aa)
P53/p73-bUncharacterized protein. (419 aa)
LOC100182351Plasminogen-like; Belongs to the peptidase S1 family. (575 aa)
Rev-erbUncharacterized protein. (597 aa)
F6QD80_CIOINSCP domain-containing protein; Belongs to the CRISP family. (201 aa)
LOC100187015RING finger protein 10 isoform X2. (695 aa)
F6XN00_CIOINProtein kinase domain-containing protein. (251 aa)
F6PHN1_CIOINProtein kinase domain-containing protein. (1026 aa)
F6R6F3_CIOINUncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1324 aa)
nachr-3Uncharacterized protein. (604 aa)
F6TBE2_CIOINUncharacterized protein. (444 aa)
F7APX0_CIOINUncharacterized protein. (1090 aa)
F6TLB6_CIOINUncharacterized protein. (891 aa)
F7BHN2_CIOINUncharacterized protein. (303 aa)
Ci-FXRNuclear receptor. (294 aa)
LOC100181489GLTP domain-containing protein. (226 aa)
F6XIK7_CIOINTyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (599 aa)
LOC100180825RING-type domain-containing protein. (215 aa)
LOC100184817Growth hormone secretagogue receptor type 1-like. (366 aa)
F6ZT56_CIOINUncharacterized protein. (83 aa)
F7B5N7_CIOINProtein kinase domain-containing protein. (353 aa)
LOC100184905TRAF3-interacting protein 1. (550 aa)
Dll-aHomeobox domain-containing protein. (453 aa)
LOC100181706Peptidase inhibitor 16 isoform X3; Belongs to the CRISP family. (403 aa)
F6PRY2_CIOINUncharacterized protein. (655 aa)
F6R946_CIOINUncharacterized protein. (246 aa)
F7AQ24_CIOINUncharacterized protein. (323 aa)
L7N0S2_CIOINUncharacterized protein. (175 aa)
mycTranscription factor protein isoform X1. (681 aa)
sfrp2Secreted frizzled-related protein isoform X1. (293 aa)
F6YQ60_CIOINSAC domain-containing protein. (706 aa)
smad4Mothers against decapentaplegic homolog. (527 aa)
Ephrin-aEphrin RBD domain-containing protein; Belongs to the ephrin family. (248 aa)
F6RGF8_CIOINUncharacterized protein. (518 aa)
LOC100185251-2Zinc finger protein. (339 aa)
F6WF44_CIOINFibrinogen C-terminal domain-containing protein. (187 aa)
F6ZG18_CIOINFERM domain-containing protein. (589 aa)
F6YC82_CIOINSARAH domain-containing protein. (138 aa)
F6PSM8_CIOINUncharacterized protein. (690 aa)
F6RS66_CIOINProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (462 aa)
F6QQZ3_CIOINThioredoxin domain-containing protein. (202 aa)
zf(fyve)-11Uncharacterized protein. (717 aa)
F6QP05_CIOING_PROTEIN_RECEP_F1_2 domain-containing protein. (291 aa)
LOC100181289Cyclin-dependent-like kinase 5; Belongs to the protein kinase superfamily. (292 aa)
F6TZD2_CIOINProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (175 aa)
F6YAC3_CIOINSenescence domain-containing protein. (116 aa)
LOC100187208OTU domain-containing protein 5. (592 aa)
F6YRI1_CIOINUncharacterized protein. (742 aa)
F6Y836_CIOINUncharacterized protein. (557 aa)
F6UL80_CIOINHomeobox domain-containing protein. (287 aa)
LOC104266675Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (226 aa)
LOC100185679Stanniocalcin-like. (237 aa)
F7AP04_CIOINUncharacterized protein. (313 aa)
moxTranscription factor protein. (176 aa)
F6X5U2_CIOINArginase. (373 aa)
LOC619278Uncharacterized protein. (1166 aa)
F6T7M7_CIOINUncharacterized protein. (492 aa)
F6X4F9_CIOINUncharacterized protein. (262 aa)
F7AA01_CIOINGlucosylceramidase. (561 aa)
F7A9X0_CIOINProtein kinase domain-containing protein. (772 aa)
LOC100178394F-box only protein 7. (515 aa)
zf(c2h2)-129Zinc finger protein ZF(C2H2)-129 isoform X1. (687 aa)
F6XRP8_CIOINMFS domain-containing protein. (445 aa)
Tgfbeta2TGF_BETA_2 domain-containing protein. (435 aa)
F7BJL5_CIOINGalectin. (357 aa)
F6PKT6_CIOINRNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (822 aa)
smad6/7Mothers against decapentaplegic homolog. (361 aa)
F6R6J0_CIOINUncharacterized protein. (585 aa)
LOC100186815Insulin-like growth factor-binding protein 5. (225 aa)
LOC100177957Tyrosine-protein kinase RYK. (593 aa)
cbfbCore-binding factor, b subunit isoform X1. (181 aa)
F6ZDN3_CIOINSema domain-containing protein. (427 aa)
F7ACP0_CIOINUncharacterized protein. (301 aa)
F6ZUG2_CIOINUncharacterized protein. (150 aa)
F7AWH6_CIOINFolate_rec domain-containing protein. (230 aa)
F7AVR1_CIOINHomeobox domain-containing protein. (418 aa)
F6Q0D8_CIOINUncharacterized protein. (1116 aa)
F6PZR6_CIOINUncharacterized protein. (728 aa)
F6PSZ6_CIOINUncharacterized protein. (205 aa)
F6PSX9_CIOINUncharacterized protein. (240 aa)
F6RH73_CIOINUncharacterized protein. (384 aa)
wnt3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (304 aa)
F6TTH0_CIOINUncharacterized protein. (426 aa)
F6ZHF5_CIOINProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (369 aa)
F6V5K2_CIOINUncharacterized protein. (467 aa)
F6V4V0_CIOINSortilin. (1459 aa)
F7BLL2_CIOING_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (332 aa)
F6YXM6_CIOINProtein kinase domain-containing protein. (722 aa)
F6YWM5_CIOINBHLH domain-containing protein. (96 aa)
LOC778708BHLH domain-containing protein. (792 aa)
F6VS24_CIOINSema domain-containing protein. (152 aa)
F7BKY1_CIOINSema domain-containing protein. (229 aa)
F7BKM3_CIOINUncharacterized protein. (506 aa)
LOC101242476Glioma pathogenesis-related protein 1-like; Belongs to the CRISP family. (336 aa)
F6QGN1_CIOINWH1 domain-containing protein. (284 aa)
F6PQC6_CIOINClaudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (217 aa)
LOC100184123Bardet-Biedl syndrome 2 protein homolog. (708 aa)
F6TDS0_CIOINUncharacterized protein. (379 aa)
F6TCY4_CIOINKringle domain-containing protein. (182 aa)
LOC100187147Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer. (158 aa)
LOC100185445Lipopolysaccharide-binding protein-like. (473 aa)
LOC100183082Lipopolysaccharide-binding protein isoform X2. (376 aa)
F6ZXH0_CIOINUncharacterized protein. (179 aa)
F6ZX31_CIOINSema domain-containing protein; Belongs to the semaphorin family. (292 aa)
F6XLS2_CIOINUncharacterized protein. (745 aa)
LOC100178267E3 ubiquitin-protein ligase PPP1R11-like. (112 aa)
F6Y6P2_CIOINSema domain-containing protein; Belongs to the semaphorin family. (483 aa)
F6U7K8_CIOINUncharacterized protein. (757 aa)
F6U7G3_CIOINHMG box domain-containing protein. (364 aa)
LOC100178900E3 ubiquitin-protein ligase PPP1R11-like. (112 aa)
LOC779004Transcription factor protein. (553 aa)
F6W3W9_CIOINUncharacterized protein. (758 aa)
F6VHE0_CIOINUncharacterized protein. (753 aa)
F6YNB1_CIOIN4HBT domain-containing protein. (143 aa)
F7AIB9_CIOINUncharacterized protein. (271 aa)
F6T2G1_CIOINUncharacterized protein. (298 aa)
H2XJG5_CIOINUncharacterized protein; Belongs to the protein kinase superfamily. (458 aa)
LOC100180326Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
H2XJY8_CIOINGlucosylceramidase. (518 aa)
H2XMV3_CIOINFibrinogen C-terminal domain-containing protein. (229 aa)
Bmp2/4TGFb_propeptide domain-containing protein. (376 aa)
H2XN97_CIOINUncharacterized protein. (200 aa)
dynlt1Tctex1-related dynein light chain. (113 aa)
H2XNX7_CIOINPCM1_C domain-containing protein. (324 aa)
H2XNY4_CIOINEAF domain-containing protein. (241 aa)
H2XPA3_CIOINRas-GEF domain-containing protein. (451 aa)
H2XPV6_CIOINBPI1 domain-containing protein. (171 aa)
Q1RL63_CIOINZinc finger protein Ci-ZF(C2H2)-144. (72 aa)
H2XQ88_CIOINFibrinogen C-terminal domain-containing protein. (331 aa)
H2XR40_CIOINRING-type domain-containing protein. (355 aa)
srfTranscription factor protein. (335 aa)
H2XS27_CIOINUncharacterized protein. (75 aa)
LOC100187478dnaJ homolog subfamily B member 11-like. (360 aa)
H2XU53_CIOINUncharacterized protein; Belongs to the heat shock protein 70 family. (643 aa)
LOC100183239AA_TRNA_LIGASE_II domain-containing protein. (510 aa)
H2XUF2_CIOINProtein kinase domain-containing protein. (202 aa)
H2XUI8_CIOINEGF-like domain-containing protein. (158 aa)
H2XUK8_CIOINBPI1 domain-containing protein. (164 aa)
atg5Autophagy protein 5; Involved in autophagic vesicle formation. (268 aa)
LOC100182647Barrier-to-autointegration factor. (90 aa)
H2XV03_CIOINUncharacterized protein. (625 aa)
LOC100179235N_BRCA1_IG domain-containing protein. (241 aa)
H2XVX2_CIOINBPI1 domain-containing protein. (219 aa)
H2XXS3_CIOINUncharacterized protein. (482 aa)
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.