STRINGSTRING
Tgfbr-iib Tgfbr-iib LOC100182084 LOC100182084 F6RYY5_CIOIN F6RYY5_CIOIN F6RZ99_CIOIN F6RZ99_CIOIN Ephd Ephd LOC778964 LOC778964 LOC100183420 LOC100183420 F6UNP2_CIOIN F6UNP2_CIOIN LOC100179961 LOC100179961 F7BAT7_CIOIN F7BAT7_CIOIN fgfr fgfr LOC100176030 LOC100176030 LOC100177452 LOC100177452 F6YCG7_CIOIN F6YCG7_CIOIN F6WEC9_CIOIN F6WEC9_CIOIN F6ZGR3_CIOIN F6ZGR3_CIOIN zf(ring)-55 zf(ring)-55 F6XQM9_CIOIN F6XQM9_CIOIN Tgfbeta2 Tgfbeta2 LOC100176488 LOC100176488 LOC100186901 LOC100186901 F6QX80_CIOIN F6QX80_CIOIN F6RC10_CIOIN F6RC10_CIOIN LOC100177957 LOC100177957 F7BHD6_CIOIN F7BHD6_CIOIN LOC100180099 LOC100180099 F6SXX6_CIOIN F6SXX6_CIOIN F6ZLD5_CIOIN F6ZLD5_CIOIN F6VYU2_CIOIN F6VYU2_CIOIN F7BEK1_CIOIN F7BEK1_CIOIN F7ATM0_CIOIN F7ATM0_CIOIN F6XCT9_CIOIN F6XCT9_CIOIN F6RMP9_CIOIN F6RMP9_CIOIN F6V4V0_CIOIN F6V4V0_CIOIN F6YXM6_CIOIN F6YXM6_CIOIN F6V3E7_CIOIN F6V3E7_CIOIN Nab1/2 Nab1/2 F6QR95_CIOIN F6QR95_CIOIN Ephe Ephe F6TE72_CIOIN F6TE72_CIOIN F6Y0S7_CIOIN F6Y0S7_CIOIN F6UYY4_CIOIN F6UYY4_CIOIN nox4 nox4 F6U7K8_CIOIN F6U7K8_CIOIN LOC100186373 LOC100186373 LOC100179989 LOC100179989 F6VBZ6_CIOIN F6VBZ6_CIOIN LOC100176335 LOC100176335 F6SLD6_CIOIN F6SLD6_CIOIN F6VHE0_CIOIN F6VHE0_CIOIN LOC100183603 LOC100183603 F6X0L7_CIOIN F6X0L7_CIOIN H2XJG5_CIOIN H2XJG5_CIOIN H2XJH4_CIOIN H2XJH4_CIOIN H2XJL8_CIOIN H2XJL8_CIOIN LOC100182401 LOC100182401 H2XL40_CIOIN H2XL40_CIOIN Q1RPY5_CIOIN Q1RPY5_CIOIN H2XN97_CIOIN H2XN97_CIOIN H2XNN7_CIOIN H2XNN7_CIOIN LOC778651 LOC778651 H2XNU2_CIOIN H2XNU2_CIOIN H2XP61_CIOIN H2XP61_CIOIN H2XPA3_CIOIN H2XPA3_CIOIN H2XPE3_CIOIN H2XPE3_CIOIN H2XQ22_CIOIN H2XQ22_CIOIN H2XQ71_CIOIN H2XQ71_CIOIN H2XR98_CIOIN H2XR98_CIOIN H2XRB3_CIOIN H2XRB3_CIOIN LOC104265697 LOC104265697 H2XRP4_CIOIN H2XRP4_CIOIN H2XT32_CIOIN H2XT32_CIOIN H2XUF2_CIOIN H2XUF2_CIOIN H2XUI8_CIOIN H2XUI8_CIOIN H2XX02_CIOIN H2XX02_CIOIN H2XXC7_CIOIN H2XXC7_CIOIN H2XXJ7_CIOIN H2XXJ7_CIOIN H2XXZ3_CIOIN H2XXZ3_CIOIN H2XY70_CIOIN H2XY70_CIOIN H2XYC1_CIOIN H2XYC1_CIOIN H2XYN3_CIOIN H2XYN3_CIOIN H2XYT5_CIOIN H2XYT5_CIOIN H2XZ51_CIOIN H2XZ51_CIOIN H2Y015_CIOIN H2Y015_CIOIN LOC101242758 LOC101242758 H2Y0C2_CIOIN H2Y0C2_CIOIN H2Y0K6_CIOIN H2Y0K6_CIOIN H2Y0N7_CIOIN H2Y0N7_CIOIN LOC100179093 LOC100179093 H2Y0V6_CIOIN H2Y0V6_CIOIN LOC100183714 LOC100183714 H2Y255_CIOIN H2Y255_CIOIN H2Y296_CIOIN H2Y296_CIOIN H2Y2K8_CIOIN H2Y2K8_CIOIN H2Y306_CIOIN H2Y306_CIOIN LOC100178753 LOC100178753 LOC100184903 LOC100184903 H2Y3A0_CIOIN H2Y3A0_CIOIN LOC100185957 LOC100185957 LOC100176205 LOC100176205 LOC100180811 LOC100180811 LOC100183493 LOC100183493 LOC100175804 LOC100175804 LOC100184540 LOC100184540 Tak1/mapkkk7 Tak1/mapkkk7 F6Q062_CIOIN F6Q062_CIOIN Ephrin-a Ephrin-a F6WQ08_CIOIN F6WQ08_CIOIN LOC100181635 LOC100181635 LOC100181431 LOC100181431 F6YH10_CIOIN F6YH10_CIOIN LOC100176033 LOC100176033 LOC100181422 LOC100181422 F6R982_CIOIN F6R982_CIOIN F6QZH0_CIOIN F6QZH0_CIOIN F6X4F9_CIOIN F6X4F9_CIOIN LOC100186269 LOC100186269 LOC100178496 LOC100178496 eph3 eph3 F6W912_CIOIN F6W912_CIOIN F6WVT9_CIOIN F6WVT9_CIOIN F6SAD5_CIOIN F6SAD5_CIOIN F6VN25_CIOIN F6VN25_CIOIN LOC100180112 LOC100180112 LOC100183152 LOC100183152 LOC100184859 LOC100184859 Cifrz Cifrz L7N0T0_CIOIN L7N0T0_CIOIN Eph-like Eph-like LOC100181289 LOC100181289 F6RI21_CIOIN F6RI21_CIOIN F6RJA6_CIOIN F6RJA6_CIOIN F6PUP9_CIOIN F6PUP9_CIOIN F6RS66_CIOIN F6RS66_CIOIN LOC100183552 LOC100183552 F7B1X4_CIOIN F7B1X4_CIOIN F7BL69_CIOIN F7BL69_CIOIN F6U1X7_CIOIN F6U1X7_CIOIN Dkc1 Dkc1 F6U2M6_CIOIN F6U2M6_CIOIN zf(c2h2)-102 zf(c2h2)-102 LOC100181085 LOC100181085 Q1RLF0_CIOIN Q1RLF0_CIOIN F7B587_CIOIN F7B587_CIOIN F7B6W8_CIOIN F7B6W8_CIOIN LOC100177796 LOC100177796 F6ZM08_CIOIN F6ZM08_CIOIN F6WUM1_CIOIN F6WUM1_CIOIN F6WUP4_CIOIN F6WUP4_CIOIN F6TLX0_CIOIN F6TLX0_CIOIN F6XLJ0_CIOIN F6XLJ0_CIOIN F6Z4E6_CIOIN F6Z4E6_CIOIN F6WNH9_CIOIN F6WNH9_CIOIN F6SQ79_CIOIN F6SQ79_CIOIN F6SQA2_CIOIN F6SQA2_CIOIN F6SQE1_CIOIN F6SQE1_CIOIN F6QJH8_CIOIN F6QJH8_CIOIN F6PPP3_CIOIN F6PPP3_CIOIN Egfr1 Egfr1 F6R8W1_CIOIN F6R8W1_CIOIN Mapkk7 Mapkk7 F6WZS2_CIOIN F6WZS2_CIOIN F6XN00_CIOIN F6XN00_CIOIN mapkk3/6 mapkk3/6 LOC100186582 LOC100186582 Axin Axin F7AK99_CIOIN F7AK99_CIOIN F6W6H7_CIOIN F6W6H7_CIOIN F6WSD2_CIOIN F6WSD2_CIOIN LOC100175666 LOC100175666 F6T7F9_CIOIN F6T7F9_CIOIN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Tgfbr-iibReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (567 aa)
LOC100182084Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (461 aa)
F6RYY5_CIOINAAA_23 domain-containing protein. (400 aa)
F6RZ99_CIOINZinc-hook domain-containing protein. (477 aa)
EphdUncharacterized protein. (1048 aa)
LOC778964Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (880 aa)
LOC100183420Uncharacterized protein. (224 aa)
F6UNP2_CIOINWD_REPEATS_REGION domain-containing protein. (464 aa)
LOC100179961Recep_L_domain domain-containing protein. (200 aa)
F7BAT7_CIOINProhibitin. (271 aa)
fgfrFibroblast growth factor receptor; Receptor for basic fibroblast growth factor. (665 aa)
LOC100176030WD_REPEATS_REGION domain-containing protein. (1206 aa)
LOC100177452Uncharacterized protein. (603 aa)
F6YCG7_CIOINAdenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1086 aa)
F6WEC9_CIOINUncharacterized protein. (1002 aa)
F6ZGR3_CIOINUncharacterized protein. (670 aa)
zf(ring)-55Zinc finger protein. (323 aa)
F6XQM9_CIOINTOG domain-containing protein. (2637 aa)
Tgfbeta2TGF_BETA_2 domain-containing protein. (435 aa)
LOC100176488T-complex protein 1 subunit delta. (540 aa)
LOC100186901Poly [ADP-ribose] polymerase. (326 aa)
F6QX80_CIOINDAGKc domain-containing protein. (374 aa)
F6RC10_CIOINUncharacterized protein. (496 aa)
LOC100177957Tyrosine-protein kinase RYK. (593 aa)
F7BHD6_CIOINFHA domain-containing protein. (474 aa)
LOC100180099Ubiquitin-conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (214 aa)
F6SXX6_CIOINProtein kinase domain-containing protein. (232 aa)
F6ZLD5_CIOINProtein kinase domain-containing protein. (164 aa)
F6VYU2_CIOINReceptor protein-tyrosine kinase. (992 aa)
F7BEK1_CIOINDNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (219 aa)
F7ATM0_CIOINUncharacterized protein. (240 aa)
F6XCT9_CIOINKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (256 aa)
F6RMP9_CIOINUncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (831 aa)
F6V4V0_CIOINSortilin. (1459 aa)
F6YXM6_CIOINProtein kinase domain-containing protein. (722 aa)
F6V3E7_CIOINProtein kinase domain-containing protein. (332 aa)
Nab1/2Uncharacterized protein. (397 aa)
F6QR95_CIOINUncharacterized protein. (988 aa)
EpheUncharacterized protein. (1006 aa)
F6TE72_CIOINProtein kinase domain-containing protein. (172 aa)
F6Y0S7_CIOINProtein kinase domain-containing protein. (242 aa)
F6UYY4_CIOININCENP_ARK-bind domain-containing protein. (142 aa)
nox4FAD-binding FR-type domain-containing protein. (811 aa)
F6U7K8_CIOINUncharacterized protein. (757 aa)
LOC100186373G1/S-specific cyclin-D2-like; Belongs to the cyclin family. (299 aa)
LOC100179989PPM-type phosphatase domain-containing protein. (490 aa)
F6VBZ6_CIOINTelo_bind domain-containing protein. (527 aa)
LOC100176335Arrestin domain-containing protein 3-like. (390 aa)
F6SLD6_CIOINDeacetylase sirtuin-type domain-containing protein. (737 aa)
F6VHE0_CIOINUncharacterized protein. (753 aa)
LOC100183603Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (81 aa)
F6X0L7_CIOINFHA_2 domain-containing protein. (571 aa)
H2XJG5_CIOINUncharacterized protein; Belongs to the protein kinase superfamily. (458 aa)
H2XJH4_CIOINCyclin N-terminal domain-containing protein. (246 aa)
H2XJL8_CIOINUncharacterized protein. (292 aa)
LOC100182401Beclin 1-associated autophagy-related key regulator. (512 aa)
H2XL40_CIOINProtein kinase domain-containing protein. (1072 aa)
Q1RPY5_CIOINZinc finger protein. (579 aa)
H2XN97_CIOINUncharacterized protein. (200 aa)
H2XNN7_CIOINUncharacterized protein. (112 aa)
LOC778651Tyrosine-protein kinase receptor. (479 aa)
H2XNU2_CIOINUncharacterized protein. (214 aa)
H2XP61_CIOINH/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (236 aa)
H2XPA3_CIOINRas-GEF domain-containing protein. (451 aa)
H2XPE3_CIOINDNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (185 aa)
H2XQ22_CIOINProtein kinase domain-containing protein. (255 aa)
H2XQ71_CIOING_PROTEIN_RECEP_F1_2 domain-containing protein. (159 aa)
H2XR98_CIOINProtein kinase domain-containing protein. (365 aa)
H2XRB3_CIOINUncharacterized protein. (548 aa)
LOC104265697Chromosome transmission fidelity protein 8 homolog. (111 aa)
H2XRP4_CIOINUncharacterized protein. (126 aa)
H2XT32_CIOINUncharacterized protein. (127 aa)
H2XUF2_CIOINProtein kinase domain-containing protein. (202 aa)
H2XUI8_CIOINEGF-like domain-containing protein. (158 aa)
H2XX02_CIOINIg-like domain-containing protein. (221 aa)
H2XXC7_CIOINPhorbol-ester/DAG-type domain-containing protein. (223 aa)
H2XXJ7_CIOINUncharacterized protein. (347 aa)
H2XXZ3_CIOINUncharacterized protein. (870 aa)
H2XY70_CIOINRecep_L_domain domain-containing protein. (209 aa)
H2XYC1_CIOINFibrinogen C-terminal domain-containing protein. (320 aa)
H2XYN3_CIOINDAGKa domain-containing protein. (184 aa)
H2XYT5_CIOINUncharacterized protein. (223 aa)
H2XZ51_CIOINUncharacterized protein. (176 aa)
H2Y015_CIOINEGF-like domain-containing protein. (182 aa)
LOC101242758Protein JTB. (137 aa)
H2Y0C2_CIOINUncharacterized protein. (138 aa)
H2Y0K6_CIOINUncharacterized protein. (3252 aa)
H2Y0N7_CIOINPkinase_Tyr domain-containing protein. (196 aa)
LOC100179093AAA domain-containing protein. (329 aa)
H2Y0V6_CIOINUncharacterized protein. (204 aa)
LOC100183714G-protein coupled receptor family C group 5 member B-like. (383 aa)
H2Y255_CIOINCTCK domain-containing protein. (191 aa)
H2Y296_CIOINUncharacterized protein. (234 aa)
H2Y2K8_CIOINUncharacterized protein. (169 aa)
H2Y306_CIOINSld5 domain-containing protein. (206 aa)
LOC100178753Ig-like domain-containing protein. (150 aa)
LOC100184903Tumor protein D52 isoform X4. (180 aa)
H2Y3A0_CIOINPkinase_Tyr domain-containing protein. (84 aa)
LOC100185957Mucosa-associated lymphoid tissue lymphoma translocation protein 1-like isoform X1. (624 aa)
LOC100176205Programmed cell death protein 10. (217 aa)
LOC100180811Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. (258 aa)
LOC100183493Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. (169 aa)
LOC100175804Protein pitchfork-like. (193 aa)
LOC100184540Death domain-associated protein 6-like isoform X1. (234 aa)
Tak1/mapkkk7Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (190 aa)
F6Q062_CIOINProtein kinase domain-containing protein. (167 aa)
Ephrin-aEphrin RBD domain-containing protein; Belongs to the ephrin family. (248 aa)
F6WQ08_CIOINProtein kinase domain-containing protein. (473 aa)
LOC100181635AAA domain-containing protein. (356 aa)
LOC100181431Uncharacterized protein. (535 aa)
F6YH10_CIOINDNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (466 aa)
LOC100176033KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (263 aa)
LOC100181422Replication factor C subunit 2-like. (336 aa)
F6R982_CIOINWD_REPEATS_REGION domain-containing protein. (433 aa)
F6QZH0_CIOINProtein kinase domain-containing protein. (459 aa)
F6X4F9_CIOINUncharacterized protein. (262 aa)
LOC100186269Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. (388 aa)
LOC100178496CDK2-associated and cullin domain-containing protein 1; Belongs to the cullin family. (294 aa)
eph3Uncharacterized protein. (1002 aa)
F6W912_CIOINProtein kinase domain-containing protein. (285 aa)
F6WVT9_CIOINProtein kinase domain-containing protein. (505 aa)
F6SAD5_CIOINUncharacterized protein; Belongs to the cyclin family. (514 aa)
F6VN25_CIOINUncharacterized protein. (889 aa)
LOC100180112Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1106 aa)
LOC100183152Uncharacterized protein. (298 aa)
LOC100184859Replication factor C subunit 3-like. (355 aa)
CifrzUncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (866 aa)
L7N0T0_CIOINRanBD1 domain-containing protein. (120 aa)
Eph-likeUncharacterized protein. (1085 aa)
LOC100181289Cyclin-dependent-like kinase 5; Belongs to the protein kinase superfamily. (292 aa)
F6RI21_CIOINUncharacterized protein. (355 aa)
F6RJA6_CIOINUncharacterized protein. (322 aa)
F6PUP9_CIOINUncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (708 aa)
F6RS66_CIOINProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (462 aa)
LOC100183552ANK_REP_REGION domain-containing protein. (230 aa)
F7B1X4_CIOINWD_REPEATS_REGION domain-containing protein. (523 aa)
F7BL69_CIOINWD_REPEATS_REGION domain-containing protein. (598 aa)
F6U1X7_CIOINUncharacterized protein. (132 aa)
Dkc1Uncharacterized protein. (189 aa)
F6U2M6_CIOINPUA domain-containing protein. (528 aa)
zf(c2h2)-102ATP-dependent DNA helicase II subunit 2; Single-stranded DNA-dependent ATP-dependent helicase. (706 aa)
LOC100181085Monocyte to macrophage differentiation factor. (314 aa)
Q1RLF0_CIOINZinc finger protein (TRAF/RING)-2. (468 aa)
F7B587_CIOINUncharacterized protein. (108 aa)
F7B6W8_CIOINC2H2-type domain-containing protein. (368 aa)
LOC100177796Protein kinase domain-containing protein. (308 aa)
F6ZM08_CIOINUncharacterized protein. (782 aa)
F6WUM1_CIOINUncharacterized protein. (774 aa)
F6WUP4_CIOINUncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1014 aa)
F6TLX0_CIOINUncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (817 aa)
F6XLJ0_CIOINUncharacterized protein. (445 aa)
F6Z4E6_CIOINUncharacterized protein. (582 aa)
F6WNH9_CIOINUncharacterized protein. (219 aa)
F6SQ79_CIOINRING-type domain-containing protein. (190 aa)
F6SQA2_CIOINDTC domain-containing protein. (81 aa)
F6SQE1_CIOINUncharacterized protein. (651 aa)
F6QJH8_CIOINSMAP domain-containing protein. (487 aa)
F6PPP3_CIOINAAA domain-containing protein. (738 aa)
Egfr1Receptor protein-tyrosine kinase. (1462 aa)
F6R8W1_CIOING_PROTEIN_RECEP_F1_2 domain-containing protein. (403 aa)
Mapkk7Protein kinase domain-containing protein. (478 aa)
F6WZS2_CIOINProtein kinase domain-containing protein. (1124 aa)
F6XN00_CIOINProtein kinase domain-containing protein. (251 aa)
mapkk3/6Protein kinase domain-containing protein. (348 aa)
LOC100186582Phosphoinositide 3-kinase regulatory subunit 4. (1337 aa)
AxinUncharacterized protein. (643 aa)
F7AK99_CIOINUncharacterized protein; Belongs to the AAA ATPase family. (696 aa)
F6W6H7_CIOINProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (279 aa)
F6WSD2_CIOINBSD domain-containing protein. (400 aa)
LOC100175666MOB kinase activator 3A. (220 aa)
F6T7F9_CIOINUncharacterized protein. (480 aa)
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
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