(12 nodes) Intracellular pH reduction network (Ciona intestinalis)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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Known Interactions

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Predicted Interactions

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Your Input:
	F6W8X6_CIOIN	Uncharacterized protein. (248 aa)
	LOC100187083	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (351 aa)
	LOC100186335	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (500 aa)
	F6XVY9_CIOIN	HECT domain-containing protein. (862 aa)
	LOC100183094	Ras-related protein rab7-like. (206 aa)
	LOC100177362	Palmitoyl-protein thioesterase 1. (292 aa)
	F6R356_CIOIN	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (849 aa)
	F6PSZ6_CIOIN	Uncharacterized protein. (205 aa)
	F6PSX9_CIOIN	Uncharacterized protein. (240 aa)
	H2XU88_CIOIN	WD_REPEATS_REGION domain-containing protein. (2705 aa)
	LOC100176356	SNARE-associated protein Snapin-like. (133 aa)
	zf(u1like)-1	Zn-finger (U1-like)-1 isoform X1. (198 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6R356_CIOIN	F6W8X6_CIOIN	ENSCINP00000018032	ENSCINP00000002583	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	Uncharacterized protein.	0.985
F6R356_CIOIN	H2XU88_CIOIN	ENSCINP00000018032	ENSCINP00000033222	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	WD_REPEATS_REGION domain-containing protein.	0.560
F6R356_CIOIN	LOC100186335	ENSCINP00000018032	ENSCINP00000013764	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	0.999
F6R356_CIOIN	LOC100187083	ENSCINP00000018032	ENSCINP00000011734	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family.	0.999
F6W8X6_CIOIN	F6R356_CIOIN	ENSCINP00000002583	ENSCINP00000018032	Uncharacterized protein.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.985
F6W8X6_CIOIN	LOC100186335	ENSCINP00000002583	ENSCINP00000013764	Uncharacterized protein.	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	0.931
F6W8X6_CIOIN	LOC100187083	ENSCINP00000002583	ENSCINP00000011734	Uncharacterized protein.	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family.	0.989
H2XU88_CIOIN	F6R356_CIOIN	ENSCINP00000033222	ENSCINP00000018032	WD_REPEATS_REGION domain-containing protein.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.560
H2XU88_CIOIN	LOC100186335	ENSCINP00000033222	ENSCINP00000013764	WD_REPEATS_REGION domain-containing protein.	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	0.877
LOC100186335	F6R356_CIOIN	ENSCINP00000013764	ENSCINP00000018032	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.999
LOC100186335	F6W8X6_CIOIN	ENSCINP00000013764	ENSCINP00000002583	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	Uncharacterized protein.	0.931
LOC100186335	H2XU88_CIOIN	ENSCINP00000013764	ENSCINP00000033222	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	WD_REPEATS_REGION domain-containing protein.	0.877
LOC100186335	LOC100187083	ENSCINP00000013764	ENSCINP00000011734	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family.	0.999
LOC100187083	F6R356_CIOIN	ENSCINP00000011734	ENSCINP00000018032	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.999
LOC100187083	F6W8X6_CIOIN	ENSCINP00000011734	ENSCINP00000002583	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family.	Uncharacterized protein.	0.989
LOC100187083	LOC100186335	ENSCINP00000011734	ENSCINP00000013764	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family.	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	0.999