(26 nodes) Regulation of intracellular pH network (Ciona intestinalis)

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Your Input:
	F7A1Y9_CIOIN	Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. (422 aa)
	F6W0Q4_CIOIN	GDT1 family protein. (253 aa)
	F6W8X6_CIOIN	Uncharacterized protein. (248 aa)
	F6XL93_CIOIN	Anion exchange protein. (1079 aa)
	F6SKI3_CIOIN	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (654 aa)
	LOC100187083	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (351 aa)
	F6TCT1_CIOIN	Anion exchange protein. (1074 aa)
	LOC100186335	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (500 aa)
	F6XVY9_CIOIN	HECT domain-containing protein. (862 aa)
	LOC100183094	Ras-related protein rab7-like. (206 aa)
	LOC100177362	Palmitoyl-protein thioesterase 1. (292 aa)
	LOC100177133	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (520 aa)
	F6R356_CIOIN	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (849 aa)
	F6R798_CIOIN	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (678 aa)
	F6U8E4_CIOIN	Na_H_Exchanger domain-containing protein. (231 aa)
	F6U823_CIOIN	Na_H_Exchanger domain-containing protein. (313 aa)
	F7ABC0_CIOIN	Cyclic nucleotide-binding domain-containing protein. (1164 aa)
	F6ZLD5_CIOIN	Protein kinase domain-containing protein. (164 aa)
	F6PSZ6_CIOIN	Uncharacterized protein. (205 aa)
	F6PSX9_CIOIN	Uncharacterized protein. (240 aa)
	LOC100186755	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (598 aa)
	H2XU88_CIOIN	WD_REPEATS_REGION domain-containing protein. (2705 aa)
	LOC100181076	Endosomal/lysosomal potassium channel TMEM175-like isoform X1. (494 aa)
	LOC100176356	SNARE-associated protein Snapin-like. (133 aa)
	LOC100178190	Calcineurin B homologous protein 1-like. (189 aa)
	zf(u1like)-1	Zn-finger (U1-like)-1 isoform X1. (198 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6R356_CIOIN	F6W8X6_CIOIN	ENSCINP00000018032	ENSCINP00000002583	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	Uncharacterized protein.	0.985
F6R356_CIOIN	H2XU88_CIOIN	ENSCINP00000018032	ENSCINP00000033222	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	WD_REPEATS_REGION domain-containing protein.	0.560
F6R356_CIOIN	LOC100177133	ENSCINP00000018032	ENSCINP00000017546	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.526
F6R356_CIOIN	LOC100186335	ENSCINP00000018032	ENSCINP00000013764	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	0.999
F6R356_CIOIN	LOC100187083	ENSCINP00000018032	ENSCINP00000011734	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family.	0.999
F6R798_CIOIN	LOC100178190	ENSCINP00000018345	ENSCINP00000035890	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.	Calcineurin B homologous protein 1-like.	0.827
F6U823_CIOIN	F6U8E4_CIOIN	ENSCINP00000019440	ENSCINP00000019439	Na_H_Exchanger domain-containing protein.	Na_H_Exchanger domain-containing protein.	0.927
F6U8E4_CIOIN	F6U823_CIOIN	ENSCINP00000019439	ENSCINP00000019440	Na_H_Exchanger domain-containing protein.	Na_H_Exchanger domain-containing protein.	0.927
F6W8X6_CIOIN	F6R356_CIOIN	ENSCINP00000002583	ENSCINP00000018032	Uncharacterized protein.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.985
F6W8X6_CIOIN	LOC100186335	ENSCINP00000002583	ENSCINP00000013764	Uncharacterized protein.	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	0.931
F6W8X6_CIOIN	LOC100187083	ENSCINP00000002583	ENSCINP00000011734	Uncharacterized protein.	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family.	0.989
H2XU88_CIOIN	F6R356_CIOIN	ENSCINP00000033222	ENSCINP00000018032	WD_REPEATS_REGION domain-containing protein.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.560
H2XU88_CIOIN	LOC100186335	ENSCINP00000033222	ENSCINP00000013764	WD_REPEATS_REGION domain-containing protein.	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	0.877
LOC100177133	F6R356_CIOIN	ENSCINP00000017546	ENSCINP00000018032	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.526
LOC100177133	LOC100186335	ENSCINP00000017546	ENSCINP00000013764	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	0.862
LOC100178190	F6R798_CIOIN	ENSCINP00000035890	ENSCINP00000018345	Calcineurin B homologous protein 1-like.	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.	0.827
LOC100186335	F6R356_CIOIN	ENSCINP00000013764	ENSCINP00000018032	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.999
LOC100186335	F6W8X6_CIOIN	ENSCINP00000013764	ENSCINP00000002583	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	Uncharacterized protein.	0.931
LOC100186335	H2XU88_CIOIN	ENSCINP00000013764	ENSCINP00000033222	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	WD_REPEATS_REGION domain-containing protein.	0.877
LOC100186335	LOC100177133	ENSCINP00000013764	ENSCINP00000017546	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.862