(13 nodes) Necrotic cell death network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100176290	Uncharacterized protein LOC100176290 isoform X4. (787 aa)
	F6PHM0_CIOIN	Uncharacterized protein. (498 aa)
	F7AW28_CIOIN	2OG-FeII_Oxy_2 domain-containing protein. (248 aa)
	F6PMK8_CIOIN	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (710 aa)
	LOC100185956	Mixed lineage kinase domain-like protein. (422 aa)
	H2Y2V4_CIOIN	Protein kinase domain-containing protein. (209 aa)
	F6VXC2_CIOIN	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (262 aa)
	F6YVN3_CIOIN	Uncharacterized protein. (165 aa)
	F6SYE0_CIOIN	Protein kinase domain-containing protein. (216 aa)
	F6ZBN8_CIOIN	CAP-Gly domain-containing protein. (292 aa)
	H2XUH0_CIOIN	Ins134_P3_kin domain-containing protein. (157 aa)
	H2XWA0_CIOIN	Ins134_P3_kin_N domain-containing protein. (92 aa)
	H2XWF6_CIOIN	Kinase; Belongs to the inositol phosphokinase (IPK) family. (416 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6PHM0_CIOIN	F6SYE0_CIOIN	ENSCINP00000006295	ENSCINP00000026311	Uncharacterized protein.	Protein kinase domain-containing protein.	0.767
F6PHM0_CIOIN	F6VXC2_CIOIN	ENSCINP00000006295	ENSCINP00000015669	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.553
F6PHM0_CIOIN	H2Y2V4_CIOIN	ENSCINP00000006295	ENSCINP00000036239	Uncharacterized protein.	Protein kinase domain-containing protein.	0.553
F6PHM0_CIOIN	LOC100176290	ENSCINP00000006295	ENSCINP00000001561	Uncharacterized protein.	Uncharacterized protein LOC100176290 isoform X4.	0.553
F6SYE0_CIOIN	F6PHM0_CIOIN	ENSCINP00000026311	ENSCINP00000006295	Protein kinase domain-containing protein.	Uncharacterized protein.	0.767
F6SYE0_CIOIN	F6ZBN8_CIOIN	ENSCINP00000026311	ENSCINP00000026477	Protein kinase domain-containing protein.	CAP-Gly domain-containing protein.	0.767
F6SYE0_CIOIN	LOC100185956	ENSCINP00000026311	ENSCINP00000011085	Protein kinase domain-containing protein.	Mixed lineage kinase domain-like protein.	0.418
F6VXC2_CIOIN	F6PHM0_CIOIN	ENSCINP00000015669	ENSCINP00000006295	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.553
F6VXC2_CIOIN	F6ZBN8_CIOIN	ENSCINP00000015669	ENSCINP00000026477	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	CAP-Gly domain-containing protein.	0.553
F6ZBN8_CIOIN	F6SYE0_CIOIN	ENSCINP00000026477	ENSCINP00000026311	CAP-Gly domain-containing protein.	Protein kinase domain-containing protein.	0.767
F6ZBN8_CIOIN	F6VXC2_CIOIN	ENSCINP00000026477	ENSCINP00000015669	CAP-Gly domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.553
F6ZBN8_CIOIN	H2Y2V4_CIOIN	ENSCINP00000026477	ENSCINP00000036239	CAP-Gly domain-containing protein.	Protein kinase domain-containing protein.	0.553
F6ZBN8_CIOIN	LOC100176290	ENSCINP00000026477	ENSCINP00000001561	CAP-Gly domain-containing protein.	Uncharacterized protein LOC100176290 isoform X4.	0.553
H2XUH0_CIOIN	H2XWF6_CIOIN	ENSCINP00000033304	ENSCINP00000033990	Ins134_P3_kin domain-containing protein.	Kinase; Belongs to the inositol phosphokinase (IPK) family.	0.472
H2XWF6_CIOIN	H2XUH0_CIOIN	ENSCINP00000033990	ENSCINP00000033304	Kinase; Belongs to the inositol phosphokinase (IPK) family.	Ins134_P3_kin domain-containing protein.	0.472
H2Y2V4_CIOIN	F6PHM0_CIOIN	ENSCINP00000036239	ENSCINP00000006295	Protein kinase domain-containing protein.	Uncharacterized protein.	0.553
H2Y2V4_CIOIN	F6ZBN8_CIOIN	ENSCINP00000036239	ENSCINP00000026477	Protein kinase domain-containing protein.	CAP-Gly domain-containing protein.	0.553
LOC100176290	F6PHM0_CIOIN	ENSCINP00000001561	ENSCINP00000006295	Uncharacterized protein LOC100176290 isoform X4.	Uncharacterized protein.	0.553
LOC100176290	F6ZBN8_CIOIN	ENSCINP00000001561	ENSCINP00000026477	Uncharacterized protein LOC100176290 isoform X4.	CAP-Gly domain-containing protein.	0.553
LOC100185956	F6SYE0_CIOIN	ENSCINP00000011085	ENSCINP00000026311	Mixed lineage kinase domain-like protein.	Protein kinase domain-containing protein.	0.418