(21 nodes) Protein K63-linked ubiquitination network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	H2XYT4_CIOIN	Uncharacterized protein. (423 aa)
	LOC100176962	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
	LOC100178442	MATH domain-containing protein. (204 aa)
	H2Y213_CIOIN	Uncharacterized protein. (124 aa)
	Q1RPY5_CIOIN	Zinc finger protein. (579 aa)
	H2XKE2_CIOIN	Uncharacterized protein. (2486 aa)
	zf(ring)-23	RING-type domain-containing protein. (319 aa)
	LOC100179623	TNF receptor-associated factor 3-like isoform X1. (351 aa)
	F7A9C9_CIOIN	Uncharacterized protein. (337 aa)
	F6XKR6_CIOIN	Uncharacterized protein. (180 aa)
	LOC100182334	Ubiquitin-conjugating enzyme E2 G1; Belongs to the ubiquitin-conjugating enzyme family. (167 aa)
	F6W673_CIOIN	RBR-type E3 ubiquitin transferase. (502 aa)
	LOC100182651	E3 ubiquitin-protein ligase RNF4 isoform X1. (224 aa)
	F6RKQ2_CIOIN	Uncharacterized protein. (437 aa)
	LOC100187055	SEFIR domain-containing protein. (513 aa)
	LOC100175624	Ubiquitin-conjugating enzyme E2-17 kDa; Belongs to the ubiquitin-conjugating enzyme family. (148 aa)
	LOC100184240	Ubiquitin-conjugating enzyme E2 35-like isoform X2; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
	LOC100184576	TNF receptor-associated factor 3-like. (290 aa)
	F6VZ78_CIOIN	MATH domain-containing protein. (193 aa)
	F7B012_CIOIN	UBIQUITIN_CONJUGAT_2 domain-containing protein. (130 aa)
	LOC100178481	TNF receptor-associated factor 3. (369 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6VZ78_CIOIN	F7B012_CIOIN	ENSCINP00000003143	ENSCINP00000002039	MATH domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.402
F6VZ78_CIOIN	Q1RPY5_CIOIN	ENSCINP00000003143	ENSCINP00000030768	MATH domain-containing protein.	Zinc finger protein.	0.723
F6XKR6_CIOIN	F7B012_CIOIN	ENSCINP00000021321	ENSCINP00000002039	Uncharacterized protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.622
F6XKR6_CIOIN	LOC100182334	ENSCINP00000021321	ENSCINP00000017801	Uncharacterized protein.	Ubiquitin-conjugating enzyme E2 G1; Belongs to the ubiquitin-conjugating enzyme family.	0.523
F7A9C9_CIOIN	F7B012_CIOIN	ENSCINP00000023645	ENSCINP00000002039	Uncharacterized protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.622
F7A9C9_CIOIN	LOC100182334	ENSCINP00000023645	ENSCINP00000017801	Uncharacterized protein.	Ubiquitin-conjugating enzyme E2 G1; Belongs to the ubiquitin-conjugating enzyme family.	0.523
F7B012_CIOIN	F6VZ78_CIOIN	ENSCINP00000002039	ENSCINP00000003143	UBIQUITIN_CONJUGAT_2 domain-containing protein.	MATH domain-containing protein.	0.402
F7B012_CIOIN	F6XKR6_CIOIN	ENSCINP00000002039	ENSCINP00000021321	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Uncharacterized protein.	0.622
F7B012_CIOIN	F7A9C9_CIOIN	ENSCINP00000002039	ENSCINP00000023645	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Uncharacterized protein.	0.622
F7B012_CIOIN	H2Y213_CIOIN	ENSCINP00000002039	ENSCINP00000035948	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Uncharacterized protein.	0.622
F7B012_CIOIN	LOC100175624	ENSCINP00000002039	ENSCINP00000007971	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Ubiquitin-conjugating enzyme E2-17 kDa; Belongs to the ubiquitin-conjugating enzyme family.	0.732
F7B012_CIOIN	LOC100176962	ENSCINP00000002039	ENSCINP00000034116	UBIQUITIN_CONJUGAT_2 domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.755
F7B012_CIOIN	LOC100178442	ENSCINP00000002039	ENSCINP00000031812	UBIQUITIN_CONJUGAT_2 domain-containing protein.	MATH domain-containing protein.	0.402
F7B012_CIOIN	LOC100178481	ENSCINP00000002039	ENSCINP00000001022	UBIQUITIN_CONJUGAT_2 domain-containing protein.	TNF receptor-associated factor 3.	0.402
F7B012_CIOIN	LOC100179623	ENSCINP00000002039	ENSCINP00000027890	UBIQUITIN_CONJUGAT_2 domain-containing protein.	TNF receptor-associated factor 3-like isoform X1.	0.402
F7B012_CIOIN	LOC100182334	ENSCINP00000002039	ENSCINP00000017801	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Ubiquitin-conjugating enzyme E2 G1; Belongs to the ubiquitin-conjugating enzyme family.	0.844
F7B012_CIOIN	LOC100182651	ENSCINP00000002039	ENSCINP00000014221	UBIQUITIN_CONJUGAT_2 domain-containing protein.	E3 ubiquitin-protein ligase RNF4 isoform X1.	0.560
F7B012_CIOIN	LOC100184240	ENSCINP00000002039	ENSCINP00000006560	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Ubiquitin-conjugating enzyme E2 35-like isoform X2; Belongs to the ubiquitin-conjugating enzyme family.	0.998
F7B012_CIOIN	LOC100184576	ENSCINP00000002039	ENSCINP00000005981	UBIQUITIN_CONJUGAT_2 domain-containing protein.	TNF receptor-associated factor 3-like.	0.402
F7B012_CIOIN	Q1RPY5_CIOIN	ENSCINP00000002039	ENSCINP00000030768	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Zinc finger protein.	0.682