(17 nodes) Neuron death network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	F6T2G1_CIOIN	Uncharacterized protein. (298 aa)
	H2XT29_CIOIN	Ncstrn_small domain-containing protein. (568 aa)
	H2Y2T2_CIOIN	FAT domain-containing protein. (235 aa)
	F6RJ65_CIOIN	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (268 aa)
	F6TLB6_CIOIN	Uncharacterized protein. (891 aa)
	Dll-a	Homeobox domain-containing protein. (453 aa)
	F6ZHS2_CIOIN	Uncharacterized protein. (484 aa)
	LOC100179098	dnaJ homolog subfamily C member 5 isoform X2. (187 aa)
	LOC100181289	Cyclin-dependent-like kinase 5; Belongs to the protein kinase superfamily. (292 aa)
	F6UX10_CIOIN	DNA_LIGASE_A3 domain-containing protein; Belongs to the ATP-dependent DNA ligase family. (655 aa)
	F6ZLD5_CIOIN	Protein kinase domain-containing protein. (164 aa)
	Zf(ring)-35	RING-type domain-containing protein. (462 aa)
	LOC100177850	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (326 aa)
	F6YVN3_CIOIN	Uncharacterized protein. (165 aa)
	F6W3W9_CIOIN	Uncharacterized protein. (758 aa)
	H2XMX2_CIOIN	Uncharacterized protein. (513 aa)
	ENSCINP00000030178	annotation not available (90 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6RJ65_CIOIN	F6UX10_CIOIN	ENSCINP00000001490	ENSCINP00000019410	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	DNA_LIGASE_A3 domain-containing protein; Belongs to the ATP-dependent DNA ligase family.	0.523
F6RJ65_CIOIN	H2Y2T2_CIOIN	ENSCINP00000001490	ENSCINP00000036217	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	FAT domain-containing protein.	0.949
F6T2G1_CIOIN	F6TLB6_CIOIN	ENSCINP00000029547	ENSCINP00000007196	Uncharacterized protein.	Uncharacterized protein.	0.950
F6T2G1_CIOIN	F6W3W9_CIOIN	ENSCINP00000029547	ENSCINP00000028344	Uncharacterized protein.	Uncharacterized protein.	0.946
F6TLB6_CIOIN	F6T2G1_CIOIN	ENSCINP00000007196	ENSCINP00000029547	Uncharacterized protein.	Uncharacterized protein.	0.950
F6TLB6_CIOIN	F6W3W9_CIOIN	ENSCINP00000007196	ENSCINP00000028344	Uncharacterized protein.	Uncharacterized protein.	0.949
F6UX10_CIOIN	F6RJ65_CIOIN	ENSCINP00000019410	ENSCINP00000001490	DNA_LIGASE_A3 domain-containing protein; Belongs to the ATP-dependent DNA ligase family.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.523
F6UX10_CIOIN	H2Y2T2_CIOIN	ENSCINP00000019410	ENSCINP00000036217	DNA_LIGASE_A3 domain-containing protein; Belongs to the ATP-dependent DNA ligase family.	FAT domain-containing protein.	0.523
F6UX10_CIOIN	LOC100177850	ENSCINP00000019410	ENSCINP00000031514	DNA_LIGASE_A3 domain-containing protein; Belongs to the ATP-dependent DNA ligase family.	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	0.795
F6W3W9_CIOIN	F6T2G1_CIOIN	ENSCINP00000028344	ENSCINP00000029547	Uncharacterized protein.	Uncharacterized protein.	0.946
F6W3W9_CIOIN	F6TLB6_CIOIN	ENSCINP00000028344	ENSCINP00000007196	Uncharacterized protein.	Uncharacterized protein.	0.949
H2Y2T2_CIOIN	F6RJ65_CIOIN	ENSCINP00000036217	ENSCINP00000001490	FAT domain-containing protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.949
H2Y2T2_CIOIN	F6UX10_CIOIN	ENSCINP00000036217	ENSCINP00000019410	FAT domain-containing protein.	DNA_LIGASE_A3 domain-containing protein; Belongs to the ATP-dependent DNA ligase family.	0.523
LOC100177850	F6UX10_CIOIN	ENSCINP00000031514	ENSCINP00000019410	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	DNA_LIGASE_A3 domain-containing protein; Belongs to the ATP-dependent DNA ligase family.	0.795