(46 nodes) Positive regulation of protein serine/threonine kinase activity network (Ciona intestinalis)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	H2XRB3_CIOIN	Uncharacterized protein. (548 aa)
	F6ZGR3_CIOIN	Uncharacterized protein. (670 aa)
	F6WEC9_CIOIN	Uncharacterized protein. (1002 aa)
	LOC100176030	WD_REPEATS_REGION domain-containing protein. (1206 aa)
	LOC100182084	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (461 aa)
	F6WSD2_CIOIN	BSD domain-containing protein. (400 aa)
	F6WZS2_CIOIN	Protein kinase domain-containing protein. (1124 aa)
	Mapkk7	Protein kinase domain-containing protein. (478 aa)
	Dkc1	Uncharacterized protein. (189 aa)
	F6U1X7_CIOIN	Uncharacterized protein. (132 aa)
	LOC100176033	KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (263 aa)
	Tak1/mapkkk7	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (190 aa)
	LOC100183552	ANK_REP_REGION domain-containing protein. (230 aa)
	Cifrz	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (866 aa)
	LOC100183152	Uncharacterized protein. (298 aa)
	LOC100180112	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1106 aa)
	F6SAD5_CIOIN	Uncharacterized protein; Belongs to the cyclin family. (514 aa)
	F6W912_CIOIN	Protein kinase domain-containing protein. (285 aa)
	F6X4F9_CIOIN	Uncharacterized protein. (262 aa)
	zf(ring)-55	Zinc finger protein. (323 aa)
	LOC100186901	Poly [ADP-ribose] polymerase. (326 aa)
	F6ZLD5_CIOIN	Protein kinase domain-containing protein. (164 aa)
	F7ATM0_CIOIN	Uncharacterized protein. (240 aa)
	F6V3E7_CIOIN	Protein kinase domain-containing protein. (332 aa)
	F6TE72_CIOIN	Protein kinase domain-containing protein. (172 aa)
	F6UYY4_CIOIN	INCENP_ARK-bind domain-containing protein. (142 aa)
	nox4	FAD-binding FR-type domain-containing protein. (811 aa)
	LOC100186373	G1/S-specific cyclin-D2-like; Belongs to the cyclin family. (299 aa)
	LOC100179989	PPM-type phosphatase domain-containing protein. (490 aa)
	F6SLD6_CIOIN	Deacetylase sirtuin-type domain-containing protein. (737 aa)
	LOC100183603	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (81 aa)
	H2XJG5_CIOIN	Uncharacterized protein; Belongs to the protein kinase superfamily. (458 aa)
	H2XJH4_CIOIN	Cyclin N-terminal domain-containing protein. (246 aa)
	H2XJL8_CIOIN	Uncharacterized protein. (292 aa)
	H2XL40_CIOIN	Protein kinase domain-containing protein. (1072 aa)
	Q1RPY5_CIOIN	Zinc finger protein. (579 aa)
	H2XN97_CIOIN	Uncharacterized protein. (200 aa)
	H2XPA3_CIOIN	Ras-GEF domain-containing protein. (451 aa)
	H2XXJ7_CIOIN	Uncharacterized protein. (347 aa)
	H2XZ51_CIOIN	Uncharacterized protein. (176 aa)
	H2Y0K6_CIOIN	Uncharacterized protein. (3252 aa)
	H2Y0N7_CIOIN	Pkinase_Tyr domain-containing protein. (196 aa)
	H2Y296_CIOIN	Uncharacterized protein. (234 aa)
	H2Y2K8_CIOIN	Uncharacterized protein. (169 aa)
	LOC100184903	Tumor protein D52 isoform X4. (180 aa)
	LOC100176205	Programmed cell death protein 10. (217 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cifrz	Mapkk7	ENSCINP00000014064	ENSCINP00000005970	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein kinase domain-containing protein.	0.489
Dkc1	F6U1X7_CIOIN	ENSCINP00000009520	ENSCINP00000009527	Uncharacterized protein.	Uncharacterized protein.	0.926
Dkc1	F6W912_CIOIN	ENSCINP00000009520	ENSCINP00000014554	Uncharacterized protein.	Protein kinase domain-containing protein.	0.944
F6SAD5_CIOIN	LOC100186373	ENSCINP00000014389	ENSCINP00000026930	Uncharacterized protein; Belongs to the cyclin family.	G1/S-specific cyclin-D2-like; Belongs to the cyclin family.	0.537
F6SAD5_CIOIN	zf(ring)-55	ENSCINP00000014389	ENSCINP00000016979	Uncharacterized protein; Belongs to the cyclin family.	Zinc finger protein.	0.873
F6SLD6_CIOIN	nox4	ENSCINP00000027486	ENSCINP00000026729	Deacetylase sirtuin-type domain-containing protein.	FAD-binding FR-type domain-containing protein.	0.475
F6TE72_CIOIN	H2XJG5_CIOIN	ENSCINP00000025624	ENSCINP00000029797	Protein kinase domain-containing protein.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.458
F6U1X7_CIOIN	Dkc1	ENSCINP00000009527	ENSCINP00000009520	Uncharacterized protein.	Uncharacterized protein.	0.926
F6U1X7_CIOIN	F6W912_CIOIN	ENSCINP00000009527	ENSCINP00000014554	Uncharacterized protein.	Protein kinase domain-containing protein.	0.735
F6W912_CIOIN	Dkc1	ENSCINP00000014554	ENSCINP00000009520	Protein kinase domain-containing protein.	Uncharacterized protein.	0.944
F6W912_CIOIN	F6U1X7_CIOIN	ENSCINP00000014554	ENSCINP00000009527	Protein kinase domain-containing protein.	Uncharacterized protein.	0.735
F6WEC9_CIOIN	LOC100176030	ENSCINP00000000607	ENSCINP00000001261	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.858
F6WZS2_CIOIN	F7ATM0_CIOIN	ENSCINP00000005759	ENSCINP00000023604	Protein kinase domain-containing protein.	Uncharacterized protein.	0.540
F6X4F9_CIOIN	H2XN97_CIOIN	ENSCINP00000015954	ENSCINP00000031130	Uncharacterized protein.	Uncharacterized protein.	0.413
F6X4F9_CIOIN	H2XPA3_CIOIN	ENSCINP00000015954	ENSCINP00000031486	Uncharacterized protein.	Ras-GEF domain-containing protein.	0.900
F7ATM0_CIOIN	F6WZS2_CIOIN	ENSCINP00000023604	ENSCINP00000005759	Uncharacterized protein.	Protein kinase domain-containing protein.	0.540
F7ATM0_CIOIN	H2XZ51_CIOIN	ENSCINP00000023604	ENSCINP00000034935	Uncharacterized protein.	Uncharacterized protein.	0.900
H2XJG5_CIOIN	F6TE72_CIOIN	ENSCINP00000029797	ENSCINP00000025624	Uncharacterized protein; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein.	0.458
H2XJG5_CIOIN	H2XRB3_CIOIN	ENSCINP00000029797	ENSCINP00000032197	Uncharacterized protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.424
H2XJG5_CIOIN	H2XXJ7_CIOIN	ENSCINP00000029797	ENSCINP00000034381	Uncharacterized protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.424