(16 nodes) Cellular response to alcohol network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	F6QP05_CIOIN	G_PROTEIN_RECEP_F1_2 domain-containing protein. (291 aa)
	F6ZHS2_CIOIN	Uncharacterized protein. (484 aa)
	F6TFC4_CIOIN	LRRNT domain-containing protein. (542 aa)
	LOC100184788	Non-specific serine/threonine protein kinase. (554 aa)
	Smoothened	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (441 aa)
	F6SXK5_CIOIN	Uncharacterized protein. (504 aa)
	F6YCG7_CIOIN	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1086 aa)
	Q69HQ2_CIOIN	Adenylate cyclase; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (439 aa)
	LOC100184065	Uncharacterized protein LOC100184065. (370 aa)
	H2Y384_CIOIN	Uncharacterized protein. (77 aa)
	H2XXZ2_CIOIN	XRN1_D2_D3 domain-containing protein. (149 aa)
	F6UYT5_CIOIN	AC_N domain-containing protein. (314 aa)
	F6TZA7_CIOIN	Uncharacterized protein. (273 aa)
	F6UEA0_CIOIN	ADH_N domain-containing protein. (254 aa)
	ci-glyr	Glycine receptor precursor; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (491 aa)
	Cibeta-catenin	Uncharacterized protein. (497 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cibeta-catenin	F6TZA7_CIOIN	ENSCINP00000014417	ENSCINP00000025972	Uncharacterized protein.	Uncharacterized protein.	0.963
Cibeta-catenin	Smoothened	ENSCINP00000014417	ENSCINP00000002708	Uncharacterized protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.506
F6SXK5_CIOIN	H2XXZ2_CIOIN	ENSCINP00000002604	ENSCINP00000034526	Uncharacterized protein.	XRN1_D2_D3 domain-containing protein.	0.519
F6TZA7_CIOIN	Cibeta-catenin	ENSCINP00000025972	ENSCINP00000014417	Uncharacterized protein.	Uncharacterized protein.	0.963
F6UYT5_CIOIN	H2Y384_CIOIN	ENSCINP00000026290	ENSCINP00000036369	AC_N domain-containing protein.	Uncharacterized protein.	0.543
F6UYT5_CIOIN	Q69HQ2_CIOIN	ENSCINP00000026290	ENSCINP00000000534	AC_N domain-containing protein.	Adenylate cyclase; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.932
F6YCG7_CIOIN	Q69HQ2_CIOIN	ENSCINP00000000889	ENSCINP00000000534	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.405
H2XXZ2_CIOIN	F6SXK5_CIOIN	ENSCINP00000034526	ENSCINP00000002604	XRN1_D2_D3 domain-containing protein.	Uncharacterized protein.	0.519
H2Y384_CIOIN	F6UYT5_CIOIN	ENSCINP00000036369	ENSCINP00000026290	Uncharacterized protein.	AC_N domain-containing protein.	0.543
Q69HQ2_CIOIN	F6UYT5_CIOIN	ENSCINP00000000534	ENSCINP00000026290	Adenylate cyclase; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	AC_N domain-containing protein.	0.932
Q69HQ2_CIOIN	F6YCG7_CIOIN	ENSCINP00000000534	ENSCINP00000000889	Adenylate cyclase; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.405
Smoothened	Cibeta-catenin	ENSCINP00000002708	ENSCINP00000014417	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein.	0.506