(90 nodes) Synaptic signaling network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	F6V725_CIOIN	PDZ domain-containing protein. (141 aa)
	F6SDZ0_CIOIN	Uncharacterized protein. (787 aa)
	F6ZE72_CIOIN	MFS domain-containing protein. (227 aa)
	F6U1C4_CIOIN	Uncharacterized protein. (318 aa)
	F6VJS2_CIOIN	SH3 domain-containing protein. (461 aa)
	LOC100182857	Synaptotagmin-5-like isoform X1. (447 aa)
	LOC100180207	G_PROTEIN_RECEP_F3_4 domain-containing protein. (339 aa)
	nachr	Uncharacterized protein. (451 aa)
	LOC100176945	Protein unc-13 homolog B-like. (1518 aa)
	F6QID5_CIOIN	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (588 aa)
	nachr-2	Nicotinic acetylcholine receptor subunit precursor. (486 aa)
	Vachtp	MFS domain-containing protein. (657 aa)
	chat	Carn_acyltransf domain-containing protein; Belongs to the carnitine/choline acetyltransferase family. (759 aa)
	LOC100187015	RING finger protein 10 isoform X2. (695 aa)
	LOC100177894	Uncharacterized protein LOC100177894. (359 aa)
	LOC100183627	MYCBP-associated protein-like isoform X2. (861 aa)
	F6PLF3_CIOIN	Uncharacterized protein. (198 aa)
	nachr-3	Uncharacterized protein. (604 aa)
	F6WP04_CIOIN	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (486 aa)
	kcc	Potassium-chloride cotransporter isoform X2. (1160 aa)
	F7AQ62_CIOIN	G_PROTEIN_RECEP_F3_4 domain-containing protein. (769 aa)
	F6TLB6_CIOIN	Uncharacterized protein. (891 aa)
	F6YG13_CIOIN	Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (446 aa)
	F6YFZ5_CIOIN	Uncharacterized protein; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (445 aa)
	F6YFX5_CIOIN	Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (482 aa)
	LOC100179935	High-affinity choline transporter 1 isoform X1; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (545 aa)
	F6TTI3_CIOIN	Ubiquitin carboxyl-terminal hydrolase. (512 aa)
	F6UT38_CIOIN	Uncharacterized protein. (696 aa)
	F6USY0_CIOIN	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (514 aa)
	F6PLQ2_CIOIN	Uncharacterized protein; Belongs to the MAGUK family. (971 aa)
	F6PLL1_CIOIN	G_PROTEIN_RECEP_F1_2 domain-containing protein. (103 aa)
	F6SNI9_CIOIN	Uncharacterized protein. (252 aa)
	F7B9A9_CIOIN	Uncharacterized protein. (1197 aa)
	F6Z916_CIOIN	Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (405 aa)
	F6Y321_CIOIN	t-SNARE coiled-coil homology domain-containing protein. (236 aa)
	LOC100187137	Cilia- and flagella-associated protein 299. (233 aa)
	LOC100181289	Cyclin-dependent-like kinase 5; Belongs to the protein kinase superfamily. (292 aa)
	F7A8B4_CIOIN	Uncharacterized protein. (495 aa)
	F7A801_CIOIN	Uncharacterized protein. (389 aa)
	Syt1	Uncharacterized protein. (328 aa)
	LOC100176265	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (456 aa)
	F6W4K8_CIOIN	Uncharacterized protein. (835 aa)
	syn	Uncharacterized protein. (519 aa)
	LOC100181021	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (200 aa)
	LOC100181998	Uncharacterized protein. (519 aa)
	LOC100181813	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (509 aa)
	vglut	MFS domain-containing protein. (663 aa)
	ci-glyr	Glycine receptor precursor; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (491 aa)
	F6Z402_CIOIN	Peptidase S72 domain-containing protein. (410 aa)
	LOC100186863	PDZ domain-containing protein GIPC1. (316 aa)
	LOC100184418	Uncharacterized protein. (95 aa)
	F6U959_CIOIN	Uncharacterized protein. (948 aa)
	Nachr-2	Uncharacterized protein. (476 aa)
	F6ZLD5_CIOIN	Protein kinase domain-containing protein. (164 aa)
	nachr-5	Nicotinic acetylcholine receptor subunit precursor. (478 aa)
	Nachr-3	Neur_chan_memb domain-containing protein. (224 aa)
	Zf(ring)-35	RING-type domain-containing protein. (462 aa)
	F6ZH24_CIOIN	Uncharacterized protein. (1903 aa)
	F6YW14_CIOIN	Uncharacterized protein. (170 aa)
	LOC100181290	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (390 aa)
	F6RPN1_CIOIN	G_PROTEIN_RECEP_F3_4 domain-containing protein. (737 aa)
	F7BER6_CIOIN	RIC3 domain-containing protein. (256 aa)
	LOC100187429	Synaptosomal-associated protein; Belongs to the SNAP-25 family. (160 aa)
	F6W3W9_CIOIN	Uncharacterized protein. (758 aa)
	F6T2G1_CIOIN	Uncharacterized protein. (298 aa)
	ENSCINP00000030178	annotation not available (90 aa)
	H2XLW2_CIOIN	Uncharacterized protein; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (304 aa)
	H2XMJ2_CIOIN	Uncharacterized protein. (195 aa)
	H2XNE8_CIOIN	Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (385 aa)
	H2XQ34_CIOIN	Uncharacterized protein. (295 aa)
	H2XQB4_CIOIN	COesterase domain-containing protein. (733 aa)
	H2XRU0_CIOIN	Sec8_exocyst domain-containing protein. (843 aa)
	H2XRZ3_CIOIN	t-SNARE coiled-coil homology domain-containing protein. (76 aa)
	H2XS27_CIOIN	Uncharacterized protein. (75 aa)
	H2XSG9_CIOIN	EGF-like domain-containing protein. (223 aa)
	H2XT96_CIOIN	Neur_chan_memb domain-containing protein. (263 aa)
	H2XTC5_CIOIN	ZZ-type domain-containing protein. (347 aa)
	H2XTE8_CIOIN	C2 domain-containing protein. (167 aa)
	H2XU25_CIOIN	NtA domain-containing protein. (184 aa)
	H2XVB8_CIOIN	Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (340 aa)
	H2XXT5_CIOIN	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (104 aa)
	Nachr-4	Uncharacterized protein. (774 aa)
	H2XZB0_CIOIN	PBPe domain-containing protein; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (260 aa)
	H2XZD8_CIOIN	Uncharacterized protein. (294 aa)
	H2Y004_CIOIN	PBPe domain-containing protein; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (232 aa)
	H2Y0D6_CIOIN	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (282 aa)
	H2Y0X3_CIOIN	MFS domain-containing protein. (144 aa)
	H2Y1F3_CIOIN	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (522 aa)
	H2Y1K9_CIOIN	Uncharacterized protein. (674 aa)
	LOC100176356	SNARE-associated protein Snapin-like. (133 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6PLL1_CIOIN	F6W4K8_CIOIN	ENSCINP00000009895	ENSCINP00000016355	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Uncharacterized protein.	0.415
F6PLL1_CIOIN	F6WP04_CIOIN	ENSCINP00000009895	ENSCINP00000006703	G_PROTEIN_RECEP_F1_2 domain-containing protein.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.431
F6PLL1_CIOIN	F6YG13_CIOIN	ENSCINP00000009895	ENSCINP00000008772	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.462
F6PLL1_CIOIN	H2XT96_CIOIN	ENSCINP00000009895	ENSCINP00000032880	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Neur_chan_memb domain-containing protein.	0.429
F6PLL1_CIOIN	Nachr-3	ENSCINP00000009895	ENSCINP00000022709	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Neur_chan_memb domain-containing protein.	0.533
F6PLL1_CIOIN	Nachr-4	ENSCINP00000009895	ENSCINP00000034509	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Uncharacterized protein.	0.414
F6PLL1_CIOIN	ci-glyr	ENSCINP00000009895	ENSCINP00000018827	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Glycine receptor precursor; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.472
F6PLL1_CIOIN	nachr-3	ENSCINP00000009895	ENSCINP00000006586	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Uncharacterized protein.	0.400
F6PLQ2_CIOIN	F6W4K8_CIOIN	ENSCINP00000009884	ENSCINP00000016355	Uncharacterized protein; Belongs to the MAGUK family.	Uncharacterized protein.	0.566
F6PLQ2_CIOIN	F7A801_CIOIN	ENSCINP00000009884	ENSCINP00000013770	Uncharacterized protein; Belongs to the MAGUK family.	Uncharacterized protein.	0.434
F6PLQ2_CIOIN	F7A8B4_CIOIN	ENSCINP00000009884	ENSCINP00000013766	Uncharacterized protein; Belongs to the MAGUK family.	Uncharacterized protein.	0.434
F6PLQ2_CIOIN	H2XQB4_CIOIN	ENSCINP00000009884	ENSCINP00000031848	Uncharacterized protein; Belongs to the MAGUK family.	COesterase domain-containing protein.	0.642
F6PLQ2_CIOIN	H2Y004_CIOIN	ENSCINP00000009884	ENSCINP00000035238	Uncharacterized protein; Belongs to the MAGUK family.	PBPe domain-containing protein; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.	0.820
F6PLQ2_CIOIN	LOC100181021	ENSCINP00000009884	ENSCINP00000016651	Uncharacterized protein; Belongs to the MAGUK family.	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.	0.538
F6PLQ2_CIOIN	LOC100184418	ENSCINP00000009884	ENSCINP00000019667	Uncharacterized protein; Belongs to the MAGUK family.	Uncharacterized protein.	0.890
F6PLQ2_CIOIN	LOC100187137	ENSCINP00000009884	ENSCINP00000013102	Uncharacterized protein; Belongs to the MAGUK family.	Cilia- and flagella-associated protein 299.	0.514
F6PLQ2_CIOIN	syn	ENSCINP00000009884	ENSCINP00000016535	Uncharacterized protein; Belongs to the MAGUK family.	Uncharacterized protein.	0.411
F6QID5_CIOIN	F6SNI9_CIOIN	ENSCINP00000004907	ENSCINP00000010096	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.	Uncharacterized protein.	0.885
F6QID5_CIOIN	F6U959_CIOIN	ENSCINP00000004907	ENSCINP00000021734	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.	Uncharacterized protein.	0.787
F6QID5_CIOIN	F6Y321_CIOIN	ENSCINP00000004907	ENSCINP00000011472	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.	t-SNARE coiled-coil homology domain-containing protein.	0.943