(49 nodes) Negative regulation of cell motility network (Ciona intestinalis)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	H2Y0M3_CIOIN	CHRD domain-containing protein. (251 aa)
	LOC100179981	Uncharacterized protein. (229 aa)
	LOC100183377	Vasohibin-1-like isoform X2. (319 aa)
	LOC100185814	Ras-related protein Rap-2a. (180 aa)
	F6UJF1_CIOIN	UDENN FLCN/SMCR8-type domain-containing protein. (561 aa)
	F6XTJ3_CIOIN	Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (639 aa)
	F7B490_CIOIN	MAM domain-containing protein. (213 aa)
	F7AJJ9_CIOIN	Uncharacterized protein. (1191 aa)
	F6YDK0_CIOIN	Uncharacterized protein. (612 aa)
	F6RD62_CIOIN	Uncharacterized protein. (377 aa)
	F6WMZ2_CIOIN	PIPK domain-containing protein. (453 aa)
	F6ZM98_CIOIN	C2 NT-type domain-containing protein. (356 aa)
	F6TLB6_CIOIN	Uncharacterized protein. (891 aa)
	F6TA08_CIOIN	Ras-associating domain-containing protein. (247 aa)
	F6RYH5_CIOIN	Uncharacterized protein. (814 aa)
	F6TSN4_CIOIN	Uncharacterized protein. (784 aa)
	F6TFC4_CIOIN	LRRNT domain-containing protein. (542 aa)
	F7A8L8_CIOIN	Uncharacterized protein. (519 aa)
	F7AQ24_CIOIN	Uncharacterized protein. (323 aa)
	H2Y3K7_CIOIN	Fibrinogen C-terminal domain-containing protein. (218 aa)
	sfrp2	Secreted frizzled-related protein isoform X1. (293 aa)
	F6T2W0_CIOIN	Uncharacterized protein. (388 aa)
	F6SGS4_CIOIN	Uncharacterized protein. (229 aa)
	LOC100176657	Claudin-1. (232 aa)
	F6QP05_CIOIN	G_PROTEIN_RECEP_F1_2 domain-containing protein. (291 aa)
	F6VEQ7_CIOIN	RFX-type winged-helix domain-containing protein. (624 aa)
	LOC100185679	Stanniocalcin-like. (237 aa)
	mox	Transcription factor protein. (176 aa)
	F7A2D4_CIOIN	BPTI/Kunitz inhibitor domain-containing protein. (271 aa)
	LOC100186815	Insulin-like growth factor-binding protein 5. (225 aa)
	F6Z402_CIOIN	Peptidase S72 domain-containing protein. (410 aa)
	F6UXY9_CIOIN	ARID domain-containing protein. (428 aa)
	F6YXX9_CIOIN	Uncharacterized protein. (883 aa)
	F7BM27_CIOIN	Uncharacterized protein. (246 aa)
	F7BKM3_CIOIN	Uncharacterized protein. (506 aa)
	F6PQC6_CIOIN	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (217 aa)
	F6ZXH0_CIOIN	Uncharacterized protein. (179 aa)
	F6XLS2_CIOIN	Uncharacterized protein. (745 aa)
	F6W3W9_CIOIN	Uncharacterized protein. (758 aa)
	F6T2G1_CIOIN	Uncharacterized protein. (298 aa)
	H2XJG5_CIOIN	Uncharacterized protein; Belongs to the protein kinase superfamily. (458 aa)
	LOC100186675	AP-1 complex-associated regulatory protein isoform X1. (287 aa)
	H2XLW5_CIOIN	Dilute domain-containing protein. (191 aa)
	H2XNH4_CIOIN	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (215 aa)
	ENSCINP00000032811	annotation not available (79 aa)
	H2XTX3_CIOIN	Uncharacterized protein. (297 aa)
	H2XV03_CIOIN	Uncharacterized protein. (625 aa)
	H2XV38_CIOIN	Uncharacterized protein. (159 aa)
	LOC100177737	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (161 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6PQC6_CIOIN	LOC100186815	ENSCINP00000025375	ENSCINP00000018431	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Insulin-like growth factor-binding protein 5.	0.497
F6SGS4_CIOIN	F6T2W0_CIOIN	ENSCINP00000012417	ENSCINP00000012407	Uncharacterized protein.	Uncharacterized protein.	0.943
F6SGS4_CIOIN	H2Y0M3_CIOIN	ENSCINP00000012417	ENSCINP00000035457	Uncharacterized protein.	CHRD domain-containing protein.	0.595
F6T2G1_CIOIN	F6TLB6_CIOIN	ENSCINP00000029547	ENSCINP00000007196	Uncharacterized protein.	Uncharacterized protein.	0.950
F6T2G1_CIOIN	F6W3W9_CIOIN	ENSCINP00000029547	ENSCINP00000028344	Uncharacterized protein.	Uncharacterized protein.	0.946
F6T2G1_CIOIN	LOC100185814	ENSCINP00000029547	ENSCINP00000002384	Uncharacterized protein.	Ras-related protein Rap-2a.	0.462
F6T2W0_CIOIN	F6SGS4_CIOIN	ENSCINP00000012407	ENSCINP00000012417	Uncharacterized protein.	Uncharacterized protein.	0.943
F6T2W0_CIOIN	H2Y0M3_CIOIN	ENSCINP00000012407	ENSCINP00000035457	Uncharacterized protein.	CHRD domain-containing protein.	0.573
F6TA08_CIOIN	H2XLW5_CIOIN	ENSCINP00000008046	ENSCINP00000030647	Ras-associating domain-containing protein.	Dilute domain-containing protein.	0.920
F6TA08_CIOIN	H2XNH4_CIOIN	ENSCINP00000008046	ENSCINP00000031207	Ras-associating domain-containing protein.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.406
F6TA08_CIOIN	LOC100176657	ENSCINP00000008046	ENSCINP00000013053	Ras-associating domain-containing protein.	Claudin-1.	0.406
F6TLB6_CIOIN	F6T2G1_CIOIN	ENSCINP00000007196	ENSCINP00000029547	Uncharacterized protein.	Uncharacterized protein.	0.950
F6TLB6_CIOIN	F6W3W9_CIOIN	ENSCINP00000007196	ENSCINP00000028344	Uncharacterized protein.	Uncharacterized protein.	0.949
F6TLB6_CIOIN	LOC100185814	ENSCINP00000007196	ENSCINP00000002384	Uncharacterized protein.	Ras-related protein Rap-2a.	0.462
F6TSN4_CIOIN	F7A8L8_CIOIN	ENSCINP00000008887	ENSCINP00000009378	Uncharacterized protein.	Uncharacterized protein.	0.700
F6W3W9_CIOIN	F6T2G1_CIOIN	ENSCINP00000028344	ENSCINP00000029547	Uncharacterized protein.	Uncharacterized protein.	0.946
F6W3W9_CIOIN	F6TLB6_CIOIN	ENSCINP00000028344	ENSCINP00000007196	Uncharacterized protein.	Uncharacterized protein.	0.949
F6W3W9_CIOIN	LOC100185814	ENSCINP00000028344	ENSCINP00000002384	Uncharacterized protein.	Ras-related protein Rap-2a.	0.462
F6WMZ2_CIOIN	F6ZM98_CIOIN	ENSCINP00000006755	ENSCINP00000006985	PIPK domain-containing protein.	C2 NT-type domain-containing protein.	0.501
F6ZM98_CIOIN	F6WMZ2_CIOIN	ENSCINP00000006985	ENSCINP00000006755	C2 NT-type domain-containing protein.	PIPK domain-containing protein.	0.501