(56 nodes) Positive regulation of chromosome organization network (Ciona intestinalis)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	H2XK76_CIOIN	Poly [ADP-ribose] polymerase. (375 aa)
	H2XN24_CIOIN	PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family. (158 aa)
	H2XNN7_CIOIN	Uncharacterized protein. (112 aa)
	H2XNP0_CIOIN	Uncharacterized protein. (243 aa)
	H2XP61_CIOIN	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (236 aa)
	H2XR98_CIOIN	Protein kinase domain-containing protein. (365 aa)
	H2XR99_CIOIN	FHA domain-containing protein. (427 aa)
	H2XRB3_CIOIN	Uncharacterized protein. (548 aa)
	LOC100184078	CDT1 domain-containing protein. (407 aa)
	H2XXJ7_CIOIN	Uncharacterized protein. (347 aa)
	H2Y2T2_CIOIN	FAT domain-containing protein. (235 aa)
	H2XNU2_CIOIN	Uncharacterized protein. (214 aa)
	F6WGY1_CIOIN	Structure-specific endonuclease subunit SLX1 homolog; Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA; Belongs to the SLX1 family. (246 aa)
	LOC100180482	Structural maintenance of chromosomes protein. (1202 aa)
	F6Q3X3_CIOIN	Fibronectin type-III domain-containing protein. (173 aa)
	F6RJ65_CIOIN	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (268 aa)
	LOC100175935	Ubiquitin carboxyl-terminal hydrolase. (328 aa)
	F6WB99_CIOIN	Uncharacterized protein. (401 aa)
	F7AE79_CIOIN	SP-RING-type domain-containing protein. (239 aa)
	Sir2-d	Deacetylase sirtuin-type domain-containing protein. (91 aa)
	F6W7K5_CIOIN	T-complex protein 1 subunit gamma. (530 aa)
	LOC100181285	T-complex protein 1 subunit gamma. (543 aa)
	F6RZ99_CIOIN	Zinc-hook domain-containing protein. (477 aa)
	F6RYY5_CIOIN	AAA_23 domain-containing protein. (400 aa)
	F6W6K0_CIOIN	Uncharacterized protein. (534 aa)
	F6UD77_CIOIN	ANK_REP_REGION domain-containing protein. (538 aa)
	Mapkk7	Protein kinase domain-containing protein. (478 aa)
	F6PL57_CIOIN	Uncharacterized protein. (1087 aa)
	F6WYC4_CIOIN	TFIIS N-terminal domain-containing protein. (494 aa)
	F7ADN1_CIOIN	Structural maintenance of chromosomes protein. (1253 aa)
	F6TV58_CIOIN	Uncharacterized protein. (147 aa)
	zf(c2h2)-102	ATP-dependent DNA helicase II subunit 2; Single-stranded DNA-dependent ATP-dependent helicase. (706 aa)
	F6U2M6_CIOIN	PUA domain-containing protein. (528 aa)
	LOC100177411	RuvB-like helicase; Belongs to the RuvB family. (467 aa)
	F6SK60_CIOIN	Uncharacterized protein. (372 aa)
	Zf(cxxc)-5	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1257 aa)
	LOC100181431	Uncharacterized protein. (535 aa)
	F6WQ08_CIOIN	Protein kinase domain-containing protein. (473 aa)
	F6QSH0_CIOIN	Uncharacterized protein. (709 aa)
	LOC100181789	AAA_23 domain-containing protein. (1070 aa)
	LOC100176488	T-complex protein 1 subunit delta. (540 aa)
	LOC100186474	Uncharacterized protein LOC100186474 isoform X1. (164 aa)
	LOC100181478	T-complex protein 1 subunit epsilon-like. (538 aa)
	LOC100176733	Cnd3 domain-containing protein. (957 aa)
	F6UX10_CIOIN	DNA_LIGASE_A3 domain-containing protein; Belongs to the ATP-dependent DNA ligase family. (655 aa)
	F6SXS1_CIOIN	Uncharacterized protein. (932 aa)
	F7ABN7_CIOIN	F-box domain-containing protein. (241 aa)
	F6PWP3_CIOIN	Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. (1233 aa)
	F6TE72_CIOIN	Protein kinase domain-containing protein. (172 aa)
	F6SQW7_CIOIN	Uncharacterized protein. (328 aa)
	F6VBZ6_CIOIN	Telo_bind domain-containing protein. (527 aa)
	F6PNC3_CIOIN	Uncharacterized protein. (1086 aa)
	nfrkb	Uncharacterized protein. (310 aa)
	F6X0L7_CIOIN	FHA_2 domain-containing protein. (571 aa)
	H2XJH5_CIOIN	ANK_REP_REGION domain-containing protein. (95 aa)
	H2XJT4_CIOIN	PHD-type domain-containing protein. (508 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6PL57_CIOIN	LOC100181789	ENSCINP00000006244	ENSCINP00000016652	Uncharacterized protein.	AAA_23 domain-containing protein.	0.471
F6PWP3_CIOIN	F6QSH0_CIOIN	ENSCINP00000025038	ENSCINP00000013216	Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.	Uncharacterized protein.	0.993
F6PWP3_CIOIN	F7ADN1_CIOIN	ENSCINP00000025038	ENSCINP00000007558	Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.	Structural maintenance of chromosomes protein.	0.995
F6PWP3_CIOIN	LOC100176733	ENSCINP00000025038	ENSCINP00000018699	Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.	Cnd3 domain-containing protein.	0.988
F6PWP3_CIOIN	LOC100180482	ENSCINP00000025038	ENSCINP00000000293	Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.	Structural maintenance of chromosomes protein.	0.995
F6PWP3_CIOIN	LOC100181789	ENSCINP00000025038	ENSCINP00000016652	Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.	AAA_23 domain-containing protein.	0.758
F6Q3X3_CIOIN	F6SXS1_CIOIN	ENSCINP00000001049	ENSCINP00000019485	Fibronectin type-III domain-containing protein.	Uncharacterized protein.	0.984
F6QSH0_CIOIN	F6PWP3_CIOIN	ENSCINP00000013216	ENSCINP00000025038	Uncharacterized protein.	Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.	0.993
F6QSH0_CIOIN	F7ADN1_CIOIN	ENSCINP00000013216	ENSCINP00000007558	Uncharacterized protein.	Structural maintenance of chromosomes protein.	0.999
F6QSH0_CIOIN	H2XR98_CIOIN	ENSCINP00000013216	ENSCINP00000032182	Uncharacterized protein.	Protein kinase domain-containing protein.	0.424
F6QSH0_CIOIN	LOC100176733	ENSCINP00000013216	ENSCINP00000018699	Uncharacterized protein.	Cnd3 domain-containing protein.	0.999
F6QSH0_CIOIN	LOC100180482	ENSCINP00000013216	ENSCINP00000000293	Uncharacterized protein.	Structural maintenance of chromosomes protein.	0.999
F6QSH0_CIOIN	LOC100181789	ENSCINP00000013216	ENSCINP00000016652	Uncharacterized protein.	AAA_23 domain-containing protein.	0.872
F6RJ65_CIOIN	F6RYY5_CIOIN	ENSCINP00000001490	ENSCINP00000003245	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	AAA_23 domain-containing protein.	0.707
F6RJ65_CIOIN	F6RZ99_CIOIN	ENSCINP00000001490	ENSCINP00000003235	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Zinc-hook domain-containing protein.	0.707
F6RJ65_CIOIN	F6SK60_CIOIN	ENSCINP00000001490	ENSCINP00000010637	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.454
F6RJ65_CIOIN	F6TV58_CIOIN	ENSCINP00000001490	ENSCINP00000008579	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.969
F6RJ65_CIOIN	F6UX10_CIOIN	ENSCINP00000001490	ENSCINP00000019410	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	DNA_LIGASE_A3 domain-containing protein; Belongs to the ATP-dependent DNA ligase family.	0.523
F6RJ65_CIOIN	F6WGY1_CIOIN	ENSCINP00000001490	ENSCINP00000000037	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Structure-specific endonuclease subunit SLX1 homolog; Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA; Belongs to the SLX1 family.	0.481
F6RJ65_CIOIN	H2XJH5_CIOIN	ENSCINP00000001490	ENSCINP00000029807	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	ANK_REP_REGION domain-containing protein.	0.819