STRINGSTRING
H2XTN0_CIOIN H2XTN0_CIOIN LOC100183745 LOC100183745 LOC100182449 LOC100182449 LOC100183765 LOC100183765 LOC100185508 LOC100185508 LOC100183259 LOC100183259 F6YWB6_CIOIN F6YWB6_CIOIN F6RJ65_CIOIN F6RJ65_CIOIN Zf(c2h2)-69 Zf(c2h2)-69 F6SIX8_CIOIN F6SIX8_CIOIN LOC100177158 LOC100177158 LOC100175516 LOC100175516 LOC100186483 LOC100186483 F6WRF3_CIOIN F6WRF3_CIOIN LOC100179977 LOC100179977 LOC100179894 LOC100179894 F6QHS0_CIOIN F6QHS0_CIOIN F6X153_CIOIN F6X153_CIOIN LOC100178939 LOC100178939 LOC100185465 LOC100185465 F6RCY1_CIOIN F6RCY1_CIOIN F6QDE3_CIOIN F6QDE3_CIOIN F7BBJ6_CIOIN F7BBJ6_CIOIN LOC100177507 LOC100177507 LOC100183393 LOC100183393 F6ZN98_CIOIN F6ZN98_CIOIN LOC100182742 LOC100182742 F6YSX7_CIOIN F6YSX7_CIOIN F7AXN3_CIOIN F7AXN3_CIOIN LOC100175749 LOC100175749 LOC100177492 LOC100177492 F6YGC1_CIOIN F6YGC1_CIOIN LOC100179870 LOC100179870 F7BMT8_CIOIN F7BMT8_CIOIN F6U2M6_CIOIN F6U2M6_CIOIN LOC100180728 LOC100180728 LOC100177120 LOC100177120 LOC100186181 LOC100186181 LOC100187346 LOC100187346 F6ZL99_CIOIN F6ZL99_CIOIN F6RXF3_CIOIN F6RXF3_CIOIN LOC100184614 LOC100184614 F7BQ53_CIOIN F7BQ53_CIOIN F6U609_CIOIN F6U609_CIOIN F6U5V8_CIOIN F6U5V8_CIOIN LOC100183227 LOC100183227 F6ZQY6_CIOIN F6ZQY6_CIOIN LOC100186454 LOC100186454 LOC100181113 LOC100181113 F6YXI8_CIOIN F6YXI8_CIOIN LOC100181970 LOC100181970 LOC100175151 LOC100175151 F6QPL4_CIOIN F6QPL4_CIOIN LOC100177118 LOC100177118 LOC100180054 LOC100180054 LOC100176171 LOC100176171 F6VJW8_CIOIN F6VJW8_CIOIN F6ZIU2_CIOIN F6ZIU2_CIOIN F6S4U2_CIOIN F6S4U2_CIOIN F6W282_CIOIN F6W282_CIOIN LOC100175786 LOC100175786 LOC100186763 LOC100186763 APTX APTX F6R407_CIOIN F6R407_CIOIN LOC100179058 LOC100179058 LOC100183682 LOC100183682 F6W132_CIOIN F6W132_CIOIN LOC100180019 LOC100180019 F6ZUU0_CIOIN F6ZUU0_CIOIN F6XG84_CIOIN F6XG84_CIOIN F6PI67_CIOIN F6PI67_CIOIN LOC100184647 LOC100184647 F6SQ32_CIOIN F6SQ32_CIOIN LOC100178283 LOC100178283 LOC100179576 LOC100179576 LOC100185530 LOC100185530 F6TBF1_CIOIN F6TBF1_CIOIN LOC100187123 LOC100187123 F6XVJ4_CIOIN F6XVJ4_CIOIN LOC100185848 LOC100185848 LOC100182246 LOC100182246 F6WS50_CIOIN F6WS50_CIOIN F6RBK2_CIOIN F6RBK2_CIOIN LOC100175152 LOC100175152 F6V2C0_CIOIN F6V2C0_CIOIN F6QW82_CIOIN F6QW82_CIOIN F6TCX3_CIOIN F6TCX3_CIOIN F6ZWQ3_CIOIN F6ZWQ3_CIOIN F6UZ38_CIOIN F6UZ38_CIOIN LOC100182604 LOC100182604 F7BGB4_CIOIN F7BGB4_CIOIN F6T6V3_CIOIN F6T6V3_CIOIN F6Y252_CIOIN F6Y252_CIOIN nf45 nf45 H2XJG6_CIOIN H2XJG6_CIOIN H2XJP4_CIOIN H2XJP4_CIOIN LOC100178835 LOC100178835 LOC100177882 LOC100177882 LOC100178413 LOC100178413 H2XM74_CIOIN H2XM74_CIOIN H2XPB0_CIOIN H2XPB0_CIOIN H2XR28_CIOIN H2XR28_CIOIN H2XRK5_CIOIN H2XRK5_CIOIN H2XRY8_CIOIN H2XRY8_CIOIN LOC100175182 LOC100175182 H2XSM0_CIOIN H2XSM0_CIOIN H2XT24_CIOIN H2XT24_CIOIN LOC101242260 LOC101242260 LOC100182802 LOC100182802 rps13 rps13 H2XUJ7_CIOIN H2XUJ7_CIOIN H2XVJ2_CIOIN H2XVJ2_CIOIN H2XWJ4_CIOIN H2XWJ4_CIOIN H2XWZ3_CIOIN H2XWZ3_CIOIN LOC100178209 LOC100178209 H2XXU4_CIOIN H2XXU4_CIOIN H2XXZ3_CIOIN H2XXZ3_CIOIN H2XZ35_CIOIN H2XZ35_CIOIN LOC100182886 LOC100182886 LOC100179691 LOC100179691 H2XZG0_CIOIN H2XZG0_CIOIN H2XZT6_CIOIN H2XZT6_CIOIN H2Y0J7_CIOIN H2Y0J7_CIOIN H2Y0R6_CIOIN H2Y0R6_CIOIN LOC100184042 LOC100184042 H2Y1V2_CIOIN H2Y1V2_CIOIN H2Y2G5_CIOIN H2Y2G5_CIOIN H2Y2T2_CIOIN H2Y2T2_CIOIN LOC100182620 LOC100182620
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
H2XTN0_CIOINUncharacterized protein. (370 aa)
LOC100183745Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. (539 aa)
LOC100182449Methylthioribose-1-phosphate isomerase-like; Belongs to the eIF-2B alpha/beta/delta subunits family. (196 aa)
LOC100183765Protein LLP homolog. (132 aa)
LOC100185508WD repeat-containing protein 43. (630 aa)
LOC100183259Uncharacterized protein. (721 aa)
F6YWB6_CIOINNucleolar protein 6. (831 aa)
F6RJ65_CIOINUncharacterized protein; Belongs to the PI3/PI4-kinase family. (268 aa)
Zf(c2h2)-69Uncharacterized protein. (940 aa)
F6SIX8_CIOINWD_REPEATS_REGION domain-containing protein. (429 aa)
LOC10017715840S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (195 aa)
LOC100175516Uncharacterized protein. (603 aa)
LOC100186483Probable ATP-dependent RNA helicase DDX47; Belongs to the DEAD box helicase family. (449 aa)
F6WRF3_CIOIN60S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. (501 aa)
LOC100179977Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (324 aa)
LOC100179894Werner syndrome ATP-dependent helicase homolog isoform X1. (1194 aa)
F6QHS0_CIOINUncharacterized protein. (394 aa)
F6X153_CIOINUncharacterized protein. (1241 aa)
LOC100178939U3 small nucleolar ribonucleoprotein protein MPP10; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the MPP10 family. (579 aa)
LOC100185465U3 small nucleolar ribonucleoprotein protein IMP4-like. (288 aa)
F6RCY1_CIOINDNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (504 aa)
F6QDE3_CIOINBms1-type G domain-containing protein. (1061 aa)
F7BBJ6_CIOINWD_REPEATS_REGION domain-containing protein. (473 aa)
LOC10017750760S ribosomal protein L11; Belongs to the universal ribosomal protein uL5 family. (178 aa)
LOC100183393DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1141 aa)
F6ZN98_CIOINDRIM domain-containing protein. (2648 aa)
LOC100182742Nucleolar RNA helicase 2. (672 aa)
F6YSX7_CIOINRPOLD domain-containing protein. (345 aa)
F7AXN3_CIOINUncharacterized protein; Belongs to the DEAD box helicase family. (691 aa)
LOC10017574960S ribosomal protein L26. (145 aa)
LOC100177492U3 small nucleolar ribonucleoprotein protein IMP3. (181 aa)
F6YGC1_CIOINUncharacterized protein; Belongs to the DEAD box helicase family. (732 aa)
LOC100179870Peptidase_M24 domain-containing protein. (394 aa)
F7BMT8_CIOINUncharacterized protein. (188 aa)
F6U2M6_CIOINPUA domain-containing protein. (528 aa)
LOC100180728WD_REPEATS_REGION domain-containing protein. (453 aa)
LOC100177120Methanethiol oxidase. (486 aa)
LOC100186181rRNA 2'-O-methyltransferase fibrillarin. (308 aa)
LOC100187346Uncharacterized protein. (580 aa)
F6ZL99_CIOINUtp12 domain-containing protein. (238 aa)
F6RXF3_CIOINSAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (525 aa)
LOC100184614Uncharacterized protein. (516 aa)
F7BQ53_CIOINWD_REPEATS_REGION domain-containing protein. (501 aa)
F6U609_CIOINNop domain-containing protein. (533 aa)
F6U5V8_CIOINUncharacterized protein. (363 aa)
LOC100183227WD_REPEATS_REGION domain-containing protein. (708 aa)
F6ZQY6_CIOINPoly [ADP-ribose] polymerase. (537 aa)
LOC100186454Uncharacterized protein. (907 aa)
LOC100181113H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (198 aa)
F6YXI8_CIOINRibosome biogenesis protein BOP1 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat BOP1/ERB1 family. (786 aa)
LOC100181970E3 ubiquitin-protein ligase ZNRF2. (217 aa)
LOC10017515140S ribosomal protein S10. (159 aa)
F6QPL4_CIOINUncharacterized protein. (286 aa)
LOC100177118Uncharacterized protein. (411 aa)
LOC100180054U3 small nucleolar RNA-associated protein 4 homolog. (666 aa)
LOC100176171Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6-A. (389 aa)
F6VJW8_CIOINRRP7 domain-containing protein. (43 aa)
F6ZIU2_CIOINUncharacterized protein. (324 aa)
F6S4U2_CIOINCP-type G domain-containing protein. (538 aa)
F6W282_CIOINDNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family. (313 aa)
LOC100175786Ribonucleases P/MRP protein subunit POP1 isoform X1. (985 aa)
LOC10018676360S ribosomal protein L5. (296 aa)
APTXAprataxin; DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair. Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species. Catalyzes the release of adenylate groups covalently linked to 5'-phosphate termini, resulting in the production of 5'-phosphate termini that can be efficiently rejoined. Also able to hydrolyze adenosine 5'-monophosphoramidate (AMP- NH(2)) and diadenosine tetraphosphate (AppppA), b [...] (380 aa)
F6R407_CIOINUncharacterized protein. (1023 aa)
LOC100179058Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family. (680 aa)
LOC100183682Uncharacterized protein. (834 aa)
F6W132_CIOINBP28CT domain-containing protein. (414 aa)
LOC100180019RNA-binding protein PNO1. (233 aa)
F6ZUU0_CIOINRNA helicase. (595 aa)
F6XG84_CIOINU3snoRNP10 domain-containing protein. (413 aa)
F6PI67_CIOINR3H domain-containing protein. (527 aa)
LOC10018464740S ribosomal protein S25; Belongs to the eukaryotic ribosomal protein eS25 family. (112 aa)
F6SQ32_CIOINANK_REP_REGION domain-containing protein. (157 aa)
LOC100178283DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (152 aa)
LOC100179576CLP1_P domain-containing protein. (557 aa)
LOC100185530WD_REPEATS_REGION domain-containing protein. (384 aa)
F6TBF1_CIOINUncharacterized protein. (170 aa)
LOC100187123Uncharacterized protein. (225 aa)
F6XVJ4_CIOINUncharacterized protein. (733 aa)
LOC100185848Deacetylase sirtuin-type domain-containing protein. (357 aa)
LOC100182246RNA polymerase I-specific transcription initiation factor RRN3. (588 aa)
F6WS50_CIOINOBG-type G domain-containing protein. (358 aa)
F6RBK2_CIOINRibosome biogenesis protein WDR12 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat WDR12/YTM1 family. (427 aa)
LOC100175152Bis(5'-adenosyl)-triphosphatase. (154 aa)
F6V2C0_CIOINUncharacterized protein. (228 aa)
F6QW82_CIOINUncharacterized protein. (184 aa)
F6TCX3_CIOINUncharacterized protein. (167 aa)
F6ZWQ3_CIOINUncharacterized protein. (215 aa)
F6UZ38_CIOINUncharacterized protein. (203 aa)
LOC100182604Nucleolar protein 8-like. (394 aa)
F7BGB4_CIOINUncharacterized protein. (97 aa)
F6T6V3_CIOINNucleolar protein 6. (234 aa)
F6Y252_CIOINGN3L_Grn1 domain-containing protein. (71 aa)
nf45NF45 protein isoform X1. (367 aa)
H2XJG6_CIOINUncharacterized protein. (211 aa)
H2XJP4_CIOINUncharacterized protein. (368 aa)
LOC100178835Cell growth-regulating nucleolar protein-like. (284 aa)
LOC100177882Ribonuclease P protein subunit p30-like. (270 aa)
LOC100178413KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. (358 aa)
H2XM74_CIOINUncharacterized protein. (234 aa)
H2XPB0_CIOINRPOLA_N domain-containing protein. (207 aa)
H2XR28_CIOINUncharacterized protein. (263 aa)
H2XRK5_CIOINUncharacterized protein. (195 aa)
H2XRY8_CIOINRibosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (404 aa)
LOC100175182RNA helicase. (627 aa)
H2XSM0_CIOIN5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (832 aa)
H2XT24_CIOINUncharacterized protein. (376 aa)
LOC101242260DNA-directed RNA polymerases I, II, and III subunit RPABC4. (79 aa)
LOC100182802Nucleoplasmin-like protein ANO39. (331 aa)
rps1340S ribosomal protein S13; Belongs to the universal ribosomal protein uS15 family. (151 aa)
H2XUJ7_CIOINFcf2 domain-containing protein. (247 aa)
H2XVJ2_CIOINUncharacterized protein. (141 aa)
H2XWJ4_CIOINUncharacterized protein. (121 aa)
H2XWZ3_CIOINPutative rRNA methyltransferase; Probable methyltransferase involved in the maturation of rRNA and in the biogenesis of ribosomal subunits. (736 aa)
LOC100178209Nop domain-containing protein. (561 aa)
H2XXU4_CIOINUncharacterized protein. (275 aa)
H2XXZ3_CIOINUncharacterized protein. (870 aa)
H2XZ35_CIOINSAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (423 aa)
LOC100182886Ribonuclease P protein subunit p21. (132 aa)
LOC100179691Bifunctional lysine-specific demethylase and histidyl-hydroxylase; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. (458 aa)
H2XZG0_CIOINUncharacterized protein. (740 aa)
H2XZT6_CIOINSAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (682 aa)
H2Y0J7_CIOINRPOLA_N domain-containing protein. (225 aa)
H2Y0R6_CIOINMediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (227 aa)
LOC100184042Uncharacterized protein. (611 aa)
H2Y1V2_CIOINSURF6 domain-containing protein. (243 aa)
H2Y2G5_CIOINMediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (160 aa)
H2Y2T2_CIOINFAT domain-containing protein. (235 aa)
LOC100182620Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (128 aa)
Your Current Organism:
Ciona intestinalis
NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.