(8 nodes) HOPS complex network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	zf(ring)-20	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family. (841 aa)
	dsba	DSBA domain-containing protein. (186 aa)
	H2XX14_CIOIN	Uncharacterized protein. (116 aa)
	F6YU56_CIOIN	Uncharacterized protein. (351 aa)
	F6SZ37_CIOIN	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family. (844 aa)
	F6Q2U2_CIOIN	CNH domain-containing protein. (871 aa)
	F6PRZ9_CIOIN	Vps8 domain-containing protein. (1238 aa)
	LOC100185122	Uncharacterized protein. (863 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6PRZ9_CIOIN	F6Q2U2_CIOIN	ENSCINP00000013070	ENSCINP00000013314	Vps8 domain-containing protein.	CNH domain-containing protein.	0.887
F6PRZ9_CIOIN	F6SZ37_CIOIN	ENSCINP00000013070	ENSCINP00000014316	Vps8 domain-containing protein.	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	0.995
F6PRZ9_CIOIN	F6YU56_CIOIN	ENSCINP00000013070	ENSCINP00000026122	Vps8 domain-containing protein.	Uncharacterized protein.	0.937
F6PRZ9_CIOIN	H2XX14_CIOIN	ENSCINP00000013070	ENSCINP00000034198	Vps8 domain-containing protein.	Uncharacterized protein.	0.937
F6PRZ9_CIOIN	LOC100185122	ENSCINP00000013070	ENSCINP00000000564	Vps8 domain-containing protein.	Uncharacterized protein.	0.995
F6PRZ9_CIOIN	zf(ring)-20	ENSCINP00000013070	ENSCINP00000026604	Vps8 domain-containing protein.	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	0.856
F6Q2U2_CIOIN	F6PRZ9_CIOIN	ENSCINP00000013314	ENSCINP00000013070	CNH domain-containing protein.	Vps8 domain-containing protein.	0.887
F6Q2U2_CIOIN	F6SZ37_CIOIN	ENSCINP00000013314	ENSCINP00000014316	CNH domain-containing protein.	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	0.995
F6Q2U2_CIOIN	F6YU56_CIOIN	ENSCINP00000013314	ENSCINP00000026122	CNH domain-containing protein.	Uncharacterized protein.	0.914
F6Q2U2_CIOIN	H2XX14_CIOIN	ENSCINP00000013314	ENSCINP00000034198	CNH domain-containing protein.	Uncharacterized protein.	0.914
F6Q2U2_CIOIN	LOC100185122	ENSCINP00000013314	ENSCINP00000000564	CNH domain-containing protein.	Uncharacterized protein.	0.994
F6Q2U2_CIOIN	zf(ring)-20	ENSCINP00000013314	ENSCINP00000026604	CNH domain-containing protein.	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	0.994
F6SZ37_CIOIN	F6PRZ9_CIOIN	ENSCINP00000014316	ENSCINP00000013070	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	Vps8 domain-containing protein.	0.995
F6SZ37_CIOIN	F6Q2U2_CIOIN	ENSCINP00000014316	ENSCINP00000013314	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	CNH domain-containing protein.	0.995
F6SZ37_CIOIN	F6YU56_CIOIN	ENSCINP00000014316	ENSCINP00000026122	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	Uncharacterized protein.	0.954
F6SZ37_CIOIN	H2XX14_CIOIN	ENSCINP00000014316	ENSCINP00000034198	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	Uncharacterized protein.	0.954
F6SZ37_CIOIN	LOC100185122	ENSCINP00000014316	ENSCINP00000000564	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	Uncharacterized protein.	0.997
F6SZ37_CIOIN	zf(ring)-20	ENSCINP00000014316	ENSCINP00000026604	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	0.997
F6YU56_CIOIN	F6PRZ9_CIOIN	ENSCINP00000026122	ENSCINP00000013070	Uncharacterized protein.	Vps8 domain-containing protein.	0.937
F6YU56_CIOIN	F6Q2U2_CIOIN	ENSCINP00000026122	ENSCINP00000013314	Uncharacterized protein.	CNH domain-containing protein.	0.914