node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
F6VXM0_CIOIN | F6Z8U5_CIOIN | ENSCINP00000008255 | ENSCINP00000023135 | Uncharacterized protein. | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. | 0.462 |
F6VXM0_CIOIN | H2XQ19_CIOIN | ENSCINP00000008255 | ENSCINP00000031753 | Uncharacterized protein. | Aminotran_5 domain-containing protein. | 0.949 |
F6VXM0_CIOIN | KYNU | ENSCINP00000008255 | ENSCINP00000015824 | Uncharacterized protein. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. | 0.949 |
F6VXM0_CIOIN | KYNU-2 | ENSCINP00000008255 | ENSCINP00000031473 | Uncharacterized protein. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. | 0.949 |
F6VXM0_CIOIN | KYNU-3 | ENSCINP00000008255 | ENSCINP00000034805 | Uncharacterized protein. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. | 0.949 |
F6VXM0_CIOIN | LOC100181631 | ENSCINP00000008255 | ENSCINP00000025991 | Uncharacterized protein. | Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.903 |
F6VXM0_CIOIN | LOC100186313 | ENSCINP00000008255 | ENSCINP00000034361 | Uncharacterized protein. | Aminotran_5 domain-containing protein. | 0.949 |
F6Z8U5_CIOIN | F6VXM0_CIOIN | ENSCINP00000023135 | ENSCINP00000008255 | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. | Uncharacterized protein. | 0.462 |
F6Z8U5_CIOIN | H2XQ19_CIOIN | ENSCINP00000023135 | ENSCINP00000031753 | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. | Aminotran_5 domain-containing protein. | 0.968 |
F6Z8U5_CIOIN | KYNU | ENSCINP00000023135 | ENSCINP00000015824 | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. | 0.969 |
F6Z8U5_CIOIN | KYNU-2 | ENSCINP00000023135 | ENSCINP00000031473 | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. | 0.969 |
F6Z8U5_CIOIN | KYNU-3 | ENSCINP00000023135 | ENSCINP00000034805 | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. | 0.968 |
F6Z8U5_CIOIN | LOC100181631 | ENSCINP00000023135 | ENSCINP00000025991 | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. | Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.463 |
F6Z8U5_CIOIN | LOC100186313 | ENSCINP00000023135 | ENSCINP00000034361 | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. | Aminotran_5 domain-containing protein. | 0.968 |
H2XQ19_CIOIN | F6VXM0_CIOIN | ENSCINP00000031753 | ENSCINP00000008255 | Aminotran_5 domain-containing protein. | Uncharacterized protein. | 0.949 |
H2XQ19_CIOIN | F6Z8U5_CIOIN | ENSCINP00000031753 | ENSCINP00000023135 | Aminotran_5 domain-containing protein. | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. | 0.968 |
H2XQ19_CIOIN | LOC100181631 | ENSCINP00000031753 | ENSCINP00000025991 | Aminotran_5 domain-containing protein. | Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.949 |
KYNU | F6VXM0_CIOIN | ENSCINP00000015824 | ENSCINP00000008255 | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. | Uncharacterized protein. | 0.949 |
KYNU | F6Z8U5_CIOIN | ENSCINP00000015824 | ENSCINP00000023135 | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. | 0.969 |
KYNU | LOC100181631 | ENSCINP00000015824 | ENSCINP00000025991 | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. | Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.949 |