(41 nodes) Synaptic membrane network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100182001	Phosphatidylinositol-binding clathrin assembly protein LAP-like. (615 aa)
	LOC100182131	Synaptojanin-2-binding protein-like. (141 aa)
	F6UP49_CIOIN	Uncharacterized protein. (1050 aa)
	F6W8X6_CIOIN	Uncharacterized protein. (248 aa)
	LOC100176945	Protein unc-13 homolog B-like. (1518 aa)
	F6W2A7_CIOIN	Uncharacterized protein. (218 aa)
	F6VF77_CIOIN	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (870 aa)
	F6ZYQ8_CIOIN	Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. (211 aa)
	F6W1I6_CIOIN	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (956 aa)
	LOC100186942	Leukocyte cell-derived chemotaxin 1. (350 aa)
	F6RGB2_CIOIN	C2 domain-containing protein. (221 aa)
	F6PLQ2_CIOIN	Uncharacterized protein; Belongs to the MAGUK family. (971 aa)
	F6VBD0_CIOIN	Uncharacterized protein. (1989 aa)
	F6Y321_CIOIN	t-SNARE coiled-coil homology domain-containing protein. (236 aa)
	F6W4K8_CIOIN	Uncharacterized protein. (835 aa)
	Nachr	Uncharacterized protein. (357 aa)
	nachr-4	Acetylcholine receptor subunit beta-like precursor. (499 aa)
	F7BJB6_CIOIN	Uncharacterized protein. (572 aa)
	LOC100182844	Importin subunit alpha; Belongs to the importin alpha family. (529 aa)
	F6WNG6_CIOIN	CUB domain-containing protein. (527 aa)
	F6TJS8_CIOIN	Uncharacterized protein. (1202 aa)
	F6U959_CIOIN	Uncharacterized protein. (948 aa)
	nachr-5	Nicotinic acetylcholine receptor subunit precursor. (478 aa)
	Nachr-3	Neur_chan_memb domain-containing protein. (224 aa)
	F6V921_CIOIN	Uncharacterized protein. (277 aa)
	LOC100176360	SLIT and NTRK-like protein 5. (305 aa)
	LOC100181290	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (390 aa)
	LOC100180605	Uncharacterized protein. (481 aa)
	F7BF76_CIOIN	Ig-like domain-containing protein. (547 aa)
	H2XJV4_CIOIN	Uncharacterized protein. (449 aa)
	H2XKV3_CIOIN	PDZ domain-containing protein. (572 aa)
	H2XQ89_CIOIN	Uncharacterized protein. (75 aa)
	H2XRW8_CIOIN	Uncharacterized protein. (89 aa)
	H2XRZ3_CIOIN	t-SNARE coiled-coil homology domain-containing protein. (76 aa)
	H2XS74_CIOIN	Uncharacterized protein. (301 aa)
	H2XUG5_CIOIN	Uncharacterized protein. (826 aa)
	H2XUL2_CIOIN	Uncharacterized protein. (299 aa)
	H2XVS5_CIOIN	LRRNT domain-containing protein. (305 aa)
	H2XXS6_CIOIN	MoCF_biosynth domain-containing protein. (151 aa)
	H2XXW3_CIOIN	Uncharacterized protein. (851 aa)
	H2XYU9_CIOIN	ATP_Ca_trans_C domain-containing protein. (158 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6PLQ2_CIOIN	F6W4K8_CIOIN	ENSCINP00000009884	ENSCINP00000016355	Uncharacterized protein; Belongs to the MAGUK family.	Uncharacterized protein.	0.566
F6PLQ2_CIOIN	H2XKV3_CIOIN	ENSCINP00000009884	ENSCINP00000030285	Uncharacterized protein; Belongs to the MAGUK family.	PDZ domain-containing protein.	0.490
F6RGB2_CIOIN	F6U959_CIOIN	ENSCINP00000009672	ENSCINP00000021734	C2 domain-containing protein.	Uncharacterized protein.	0.900
F6RGB2_CIOIN	F6Y321_CIOIN	ENSCINP00000009672	ENSCINP00000011472	C2 domain-containing protein.	t-SNARE coiled-coil homology domain-containing protein.	0.485
F6RGB2_CIOIN	H2XRZ3_CIOIN	ENSCINP00000009672	ENSCINP00000032427	C2 domain-containing protein.	t-SNARE coiled-coil homology domain-containing protein.	0.485
F6RGB2_CIOIN	LOC100176945	ENSCINP00000009672	ENSCINP00000004445	C2 domain-containing protein.	Protein unc-13 homolog B-like.	0.845
F6U959_CIOIN	F6RGB2_CIOIN	ENSCINP00000021734	ENSCINP00000009672	Uncharacterized protein.	C2 domain-containing protein.	0.900
F6U959_CIOIN	F6Y321_CIOIN	ENSCINP00000021734	ENSCINP00000011472	Uncharacterized protein.	t-SNARE coiled-coil homology domain-containing protein.	0.650
F6U959_CIOIN	H2XRZ3_CIOIN	ENSCINP00000021734	ENSCINP00000032427	Uncharacterized protein.	t-SNARE coiled-coil homology domain-containing protein.	0.650
F6U959_CIOIN	LOC100176945	ENSCINP00000021734	ENSCINP00000004445	Uncharacterized protein.	Protein unc-13 homolog B-like.	0.958
F6UP49_CIOIN	F6VF77_CIOIN	ENSCINP00000001974	ENSCINP00000004680	Uncharacterized protein.	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.664
F6UP49_CIOIN	LOC100182001	ENSCINP00000001974	ENSCINP00000012392	Uncharacterized protein.	Phosphatidylinositol-binding clathrin assembly protein LAP-like.	0.859
F6VF77_CIOIN	F6UP49_CIOIN	ENSCINP00000004680	ENSCINP00000001974	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Uncharacterized protein.	0.664
F6VF77_CIOIN	LOC100182001	ENSCINP00000004680	ENSCINP00000012392	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Phosphatidylinositol-binding clathrin assembly protein LAP-like.	0.520
F6W2A7_CIOIN	H2XQ89_CIOIN	ENSCINP00000004644	ENSCINP00000031823	Uncharacterized protein.	Uncharacterized protein.	0.676
F6W4K8_CIOIN	F6PLQ2_CIOIN	ENSCINP00000016355	ENSCINP00000009884	Uncharacterized protein.	Uncharacterized protein; Belongs to the MAGUK family.	0.566
F6W4K8_CIOIN	Nachr-3	ENSCINP00000016355	ENSCINP00000022709	Uncharacterized protein.	Neur_chan_memb domain-containing protein.	0.422
F6Y321_CIOIN	F6RGB2_CIOIN	ENSCINP00000011472	ENSCINP00000009672	t-SNARE coiled-coil homology domain-containing protein.	C2 domain-containing protein.	0.485
F6Y321_CIOIN	F6U959_CIOIN	ENSCINP00000011472	ENSCINP00000021734	t-SNARE coiled-coil homology domain-containing protein.	Uncharacterized protein.	0.650
F6Y321_CIOIN	LOC100176945	ENSCINP00000011472	ENSCINP00000004445	t-SNARE coiled-coil homology domain-containing protein.	Protein unc-13 homolog B-like.	0.719