(5 nodes) Clathrin, heavy chain/VPS, 7-fold repeat network (Ciona intestinalis)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100185122	Uncharacterized protein. (863 aa)
	F7AMF6_CIOIN	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1635 aa)
	F7BBV8_CIOIN	CNH domain-containing protein. (856 aa)
	F6Q2U2_CIOIN	CNH domain-containing protein. (871 aa)
	zf(ring)-20	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family. (841 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6Q2U2_CIOIN	F7BBV8_CIOIN	ENSCINP00000013314	ENSCINP00000011601	CNH domain-containing protein.	CNH domain-containing protein.	0.947
F6Q2U2_CIOIN	LOC100185122	ENSCINP00000013314	ENSCINP00000000564	CNH domain-containing protein.	Uncharacterized protein.	0.994
F6Q2U2_CIOIN	zf(ring)-20	ENSCINP00000013314	ENSCINP00000026604	CNH domain-containing protein.	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	0.994
F7AMF6_CIOIN	LOC100185122	ENSCINP00000003530	ENSCINP00000000564	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Uncharacterized protein.	0.476
F7AMF6_CIOIN	zf(ring)-20	ENSCINP00000003530	ENSCINP00000026604	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	0.474
F7BBV8_CIOIN	F6Q2U2_CIOIN	ENSCINP00000011601	ENSCINP00000013314	CNH domain-containing protein.	CNH domain-containing protein.	0.947
F7BBV8_CIOIN	LOC100185122	ENSCINP00000011601	ENSCINP00000000564	CNH domain-containing protein.	Uncharacterized protein.	0.993
F7BBV8_CIOIN	zf(ring)-20	ENSCINP00000011601	ENSCINP00000026604	CNH domain-containing protein.	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	0.989
LOC100185122	F6Q2U2_CIOIN	ENSCINP00000000564	ENSCINP00000013314	Uncharacterized protein.	CNH domain-containing protein.	0.994
LOC100185122	F7AMF6_CIOIN	ENSCINP00000000564	ENSCINP00000003530	Uncharacterized protein.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.476
LOC100185122	F7BBV8_CIOIN	ENSCINP00000000564	ENSCINP00000011601	Uncharacterized protein.	CNH domain-containing protein.	0.993
LOC100185122	zf(ring)-20	ENSCINP00000000564	ENSCINP00000026604	Uncharacterized protein.	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	0.997
zf(ring)-20	F6Q2U2_CIOIN	ENSCINP00000026604	ENSCINP00000013314	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	CNH domain-containing protein.	0.994
zf(ring)-20	F7AMF6_CIOIN	ENSCINP00000026604	ENSCINP00000003530	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.474
zf(ring)-20	F7BBV8_CIOIN	ENSCINP00000026604	ENSCINP00000011601	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	CNH domain-containing protein.	0.989
zf(ring)-20	LOC100185122	ENSCINP00000026604	ENSCINP00000000564	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	Uncharacterized protein.	0.997