(53 nodes) PDZ domain network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	H2XZF1_CIOIN	PDZ domain-containing protein. (205 aa)
	H2Y1Z5_CIOIN	Uncharacterized protein. (313 aa)
	H2Y050_CIOIN	PDZ domain-containing protein. (326 aa)
	H2XYV1_CIOIN	PDZ domain-containing protein. (225 aa)
	LOC100176585	Tax1-binding protein 3. (136 aa)
	H2XUI9_CIOIN	PDZ domain-containing protein. (219 aa)
	H2XS58_CIOIN	Uncharacterized protein. (797 aa)
	H2XRX3_CIOIN	PDZ domain-containing protein. (82 aa)
	H2XRV4_CIOIN	Uncharacterized protein. (463 aa)
	H2XNL5_CIOIN	PDZ domain-containing protein. (169 aa)
	LOC100178268	Uncharacterized protein LOC100178268 isoform X1. (297 aa)
	H2XN51_CIOIN	Uncharacterized protein. (2009 aa)
	H2XKV3_CIOIN	PDZ domain-containing protein. (572 aa)
	LOC100177804	Palladin-like. (425 aa)
	F6S6P6_CIOIN	Uncharacterized protein. (372 aa)
	F6W610_CIOIN	PDZ domain-containing protein. (177 aa)
	F6YR85_CIOIN	Uncharacterized protein. (173 aa)
	F6SA56_CIOIN	PDZ domain-containing protein. (364 aa)
	F6SAC8_CIOIN	PDZ domain-containing protein. (193 aa)
	F6VRY6_CIOIN	PDZ domain-containing protein. (237 aa)
	F6YET4_CIOIN	PDZ domain-containing protein. (176 aa)
	F6PZ91_CIOIN	Uncharacterized protein. (532 aa)
	LOC100178175	PDZ domain-containing protein. (213 aa)
	F6SPE9_CIOIN	PDZ domain-containing protein. (245 aa)
	F6U959_CIOIN	Uncharacterized protein. (948 aa)
	dsh	Dishevelled homolog. (685 aa)
	LOC100186863	PDZ domain-containing protein GIPC1. (316 aa)
	F6TJS8_CIOIN	Uncharacterized protein. (1202 aa)
	F6Y9G2_CIOIN	PDZ domain-containing protein. (881 aa)
	F6W0Z5_CIOIN	PDZ domain-containing protein. (519 aa)
	F7BJB6_CIOIN	Uncharacterized protein. (572 aa)
	F6WCT6_CIOIN	PDZ domain-containing protein. (347 aa)
	LOC100179311	MAGUK p55 subfamily member 6-like; Belongs to the MAGUK family. (498 aa)
	LOC100187130	Uncharacterized protein LOC100187130. (893 aa)
	LOC100181021	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (200 aa)
	F6YND7_CIOIN	PDZ domain-containing protein. (226 aa)
	F6SSU9_CIOIN	PDZ domain-containing protein. (192 aa)
	F6X4F9_CIOIN	Uncharacterized protein. (262 aa)
	F6VBT4_CIOIN	Uncharacterized protein. (299 aa)
	F7A8B4_CIOIN	Uncharacterized protein. (495 aa)
	F6PLQ2_CIOIN	Uncharacterized protein; Belongs to the MAGUK family. (971 aa)
	Ptp	Tyrosine-protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (987 aa)
	F6RYH5_CIOIN	Uncharacterized protein. (814 aa)
	LOC100175009	Partitioning defective protein 6. (372 aa)
	F6SLU0_CIOIN	Uncharacterized protein. (444 aa)
	LOC100181746	MAGUK p55 subfamily member 7 isoform X1; Belongs to the MAGUK family. (607 aa)
	LOC100175118	Na(+)/H(+) exchange regulatory cofactor NHE-RF1. (296 aa)
	LOC100181572	LIM domain-binding protein 3-like. (333 aa)
	F6SBR8_CIOIN	PDZ domain-containing protein. (729 aa)
	F6Q5A8_CIOIN	Uncharacterized protein. (1022 aa)
	F6YW46_CIOIN	PDZ domain-containing protein. (712 aa)
	LOC100182131	Synaptojanin-2-binding protein-like. (141 aa)
	F6V725_CIOIN	PDZ domain-containing protein. (141 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6PLQ2_CIOIN	F6Y9G2_CIOIN	ENSCINP00000009884	ENSCINP00000019324	Uncharacterized protein; Belongs to the MAGUK family.	PDZ domain-containing protein.	0.428
F6PLQ2_CIOIN	F7A8B4_CIOIN	ENSCINP00000009884	ENSCINP00000013766	Uncharacterized protein; Belongs to the MAGUK family.	Uncharacterized protein.	0.434
F6PLQ2_CIOIN	H2XKV3_CIOIN	ENSCINP00000009884	ENSCINP00000030285	Uncharacterized protein; Belongs to the MAGUK family.	PDZ domain-containing protein.	0.490
F6PLQ2_CIOIN	LOC100175009	ENSCINP00000009884	ENSCINP00000008202	Uncharacterized protein; Belongs to the MAGUK family.	Partitioning defective protein 6.	0.687
F6PLQ2_CIOIN	LOC100179311	ENSCINP00000009884	ENSCINP00000017050	Uncharacterized protein; Belongs to the MAGUK family.	MAGUK p55 subfamily member 6-like; Belongs to the MAGUK family.	0.493
F6PLQ2_CIOIN	LOC100181021	ENSCINP00000009884	ENSCINP00000016651	Uncharacterized protein; Belongs to the MAGUK family.	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.	0.538
F6PZ91_CIOIN	LOC100175009	ENSCINP00000023844	ENSCINP00000008202	Uncharacterized protein.	Partitioning defective protein 6.	0.502
F6RYH5_CIOIN	LOC100175009	ENSCINP00000008326	ENSCINP00000008202	Uncharacterized protein.	Partitioning defective protein 6.	0.525
F6RYH5_CIOIN	LOC100181021	ENSCINP00000008326	ENSCINP00000016651	Uncharacterized protein.	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.	0.552
F6S6P6_CIOIN	F6WCT6_CIOIN	ENSCINP00000028190	ENSCINP00000017767	Uncharacterized protein.	PDZ domain-containing protein.	0.405
F6S6P6_CIOIN	LOC100175009	ENSCINP00000028190	ENSCINP00000008202	Uncharacterized protein.	Partitioning defective protein 6.	0.502
F6SA56_CIOIN	LOC100175009	ENSCINP00000026610	ENSCINP00000008202	PDZ domain-containing protein.	Partitioning defective protein 6.	0.978
F6SA56_CIOIN	LOC100181746	ENSCINP00000026610	ENSCINP00000005846	PDZ domain-containing protein.	MAGUK p55 subfamily member 7 isoform X1; Belongs to the MAGUK family.	0.574
F6SAC8_CIOIN	LOC100175009	ENSCINP00000026360	ENSCINP00000008202	PDZ domain-containing protein.	Partitioning defective protein 6.	0.496
F6SBR8_CIOIN	dsh	ENSCINP00000002382	ENSCINP00000019640	PDZ domain-containing protein.	Dishevelled homolog.	0.593
F6SLU0_CIOIN	LOC100175009	ENSCINP00000008090	ENSCINP00000008202	Uncharacterized protein.	Partitioning defective protein 6.	0.502
F6TJS8_CIOIN	LOC100175009	ENSCINP00000019460	ENSCINP00000008202	Uncharacterized protein.	Partitioning defective protein 6.	0.502
F6U959_CIOIN	LOC100179311	ENSCINP00000021734	ENSCINP00000017050	Uncharacterized protein.	MAGUK p55 subfamily member 6-like; Belongs to the MAGUK family.	0.460
F6V725_CIOIN	LOC100175009	ENSCINP00000000086	ENSCINP00000008202	PDZ domain-containing protein.	Partitioning defective protein 6.	0.502
F6VBT4_CIOIN	LOC100175009	ENSCINP00000015157	ENSCINP00000008202	Uncharacterized protein.	Partitioning defective protein 6.	0.502