(76 nodes) Small GTPase network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	F6VY76_CIOIN	Uncharacterized protein. (210 aa)
	LOC100185717	Uncharacterized protein. (623 aa)
	cdc42	Uncharacterized protein. (95 aa)
	rbj	Ras-associated protein Rap1 isoform X1. (267 aa)
	LOC100182595	Ras-related protein Rab-23. (243 aa)
	LOC100185814	Ras-related protein Rap-2a. (180 aa)
	F6ZBE4_CIOIN	Uncharacterized protein. (239 aa)
	LOC100179217	GTP-binding protein Rheb. (183 aa)
	LOC448957	Rac4 protein. (193 aa)
	Rac3a	Uncharacterized protein. (194 aa)
	LOC448958	Rac5 protein. (193 aa)
	LOC445702	Rac1 protein isoform X1. (192 aa)
	LOC100177212	Uncharacterized protein. (227 aa)
	F6XMN3_CIOIN	Uncharacterized protein. (223 aa)
	LOC100184914	Uncharacterized protein. (206 aa)
	LOC100178081	Ras-related protein Rab-6A. (209 aa)
	rhoc	RhoA protein. (193 aa)
	LOC100182193	Ras-related protein Rab-5B. (217 aa)
	F6ZKW1_CIOIN	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (161 aa)
	LOC100185758	Ras-related protein Rab-10-like. (202 aa)
	F6Z156_CIOIN	Uncharacterized protein. (190 aa)
	F7A669_CIOIN	Uncharacterized protein. (157 aa)
	LOC113475749	Uncharacterized protein LOC113475749. (339 aa)
	F6RFB0_CIOIN	Uncharacterized protein. (793 aa)
	LOC100183149	Uncharacterized protein. (214 aa)
	LOC100178018	Uncharacterized protein. (225 aa)
	rcl2	Rac and Cdc42-like 2 protein isoform X1. (192 aa)
	LOC100178332	Ras-related protein Rab-9B-like. (206 aa)
	LOC100177266	Uncharacterized protein. (211 aa)
	LOC100178266	Uncharacterized protein. (213 aa)
	LOC100185576	Ras-related protein Rab-18. (200 aa)
	LOC100176126	Ras-related protein Rab-14. (214 aa)
	LOC100179868	Uncharacterized protein. (199 aa)
	LOC100183094	Ras-related protein rab7-like. (206 aa)
	LOC445704	TC10 protein. (193 aa)
	F6W141_CIOIN	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (619 aa)
	LOC100183241	Ras-related protein Rab-10-like isoform X1. (207 aa)
	F6XV61_CIOIN	Uncharacterized protein. (304 aa)
	rhob	Rif protein. (249 aa)
	LOC100185283	Ras-related protein O-RAL isoform X2. (206 aa)
	LOC100175425	Ras-related protein Rab-11B-like. (217 aa)
	F6W350_CIOIN	Uncharacterized protein. (699 aa)
	Rac2	Uncharacterized protein. (192 aa)
	F6VU90_CIOIN	Uncharacterized protein. (77 aa)
	F6XND0_CIOIN	Uncharacterized protein. (233 aa)
	rcl1	Rac and Cdc42-like 1 protein. (194 aa)
	LOC113474833	Uncharacterized protein. (202 aa)
	F6UZ38_CIOIN	Uncharacterized protein. (203 aa)
	F6Y790_CIOIN	Uncharacterized protein. (207 aa)
	F7B8S2_CIOIN	Uncharacterized protein. (165 aa)
	F6VH27_CIOIN	Uncharacterized protein. (182 aa)
	LOC100182890	Uncharacterized protein. (200 aa)
	F6ZET9_CIOIN	Uncharacterized protein. (205 aa)
	LOC100182652	dnaJ homolog subfamily C member 27-like isoform X1. (206 aa)
	LOC100185850	Ras-related protein ORAB-1. (204 aa)
	LOC100175015	NF-kappa-B inhibitor-interacting Ras-like protein 2 isoform X1. (192 aa)
	H2XMB5_CIOIN	Uncharacterized protein. (116 aa)
	H2XMI8_CIOIN	Uncharacterized protein. (210 aa)
	H2XNN6_CIOIN	Uncharacterized protein. (267 aa)
	LOC100177670	Uncharacterized protein. (152 aa)
	LOC100180604	Uncharacterized protein. (236 aa)
	LOC100179082	Intraflagellar transport protein 22 homolog isoform X1. (178 aa)
	H2XRK5_CIOIN	Uncharacterized protein. (195 aa)
	H2XUB9_CIOIN	Uncharacterized protein. (224 aa)
	LOC100180756	Ras-related protein RABF2b-like. (215 aa)
	H2XWC0_CIOIN	Uncharacterized protein. (120 aa)
	LOC100182780	Ras-related protein Rab-3. (220 aa)
	LOC100181151	Ras-related protein M-Ras. (199 aa)
	LOC100177325	Ras-related protein Rab-4B. (217 aa)
	COS41.2	Putative Ras-related protein Rab-33. (212 aa)
	LOC100186168	Ras-related protein Rab-26-like. (223 aa)
	Rhou	Uncharacterized protein. (259 aa)
	Rab2	Uncharacterized protein. (198 aa)
	H2Y1U8_CIOIN	Uncharacterized protein. (232 aa)
	Rap1b	Uncharacterized protein. (184 aa)
	H2Y3T6_CIOIN	Uncharacterized protein. (196 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
COS41.2	H2XNN6_CIOIN	ENSCINP00000035150	ENSCINP00000031269	Putative Ras-related protein Rab-33.	Uncharacterized protein.	0.526
COS41.2	LOC100175425	ENSCINP00000035150	ENSCINP00000023724	Putative Ras-related protein Rab-33.	Ras-related protein Rab-11B-like.	0.460
COS41.2	LOC100178018	ENSCINP00000035150	ENSCINP00000011127	Putative Ras-related protein Rab-33.	Uncharacterized protein.	0.468
COS41.2	LOC100178081	ENSCINP00000035150	ENSCINP00000006041	Putative Ras-related protein Rab-33.	Ras-related protein Rab-6A.	0.509
COS41.2	LOC100178332	ENSCINP00000035150	ENSCINP00000012228	Putative Ras-related protein Rab-33.	Ras-related protein Rab-9B-like.	0.495
COS41.2	LOC100180756	ENSCINP00000035150	ENSCINP00000033812	Putative Ras-related protein Rab-33.	Ras-related protein RABF2b-like.	0.410
COS41.2	LOC100183149	ENSCINP00000035150	ENSCINP00000010211	Putative Ras-related protein Rab-33.	Uncharacterized protein.	0.473
COS41.2	LOC100184914	ENSCINP00000035150	ENSCINP00000005841	Putative Ras-related protein Rab-33.	Uncharacterized protein.	0.484
F6VH27_CIOIN	LOC100177325	ENSCINP00000028374	ENSCINP00000034610	Uncharacterized protein.	Ras-related protein Rab-4B.	0.417
F6VH27_CIOIN	LOC100178332	ENSCINP00000028374	ENSCINP00000012228	Uncharacterized protein.	Ras-related protein Rab-9B-like.	0.466
F6VY76_CIOIN	LOC100179082	ENSCINP00000008241	ENSCINP00000032241	Uncharacterized protein.	Intraflagellar transport protein 22 homolog isoform X1.	0.740
F6W350_CIOIN	F6ZBE4_CIOIN	ENSCINP00000023791	ENSCINP00000002716	Uncharacterized protein.	Uncharacterized protein.	0.479
F6W350_CIOIN	H2XNN6_CIOIN	ENSCINP00000023791	ENSCINP00000031269	Uncharacterized protein.	Uncharacterized protein.	0.548
F6W350_CIOIN	LOC100175425	ENSCINP00000023791	ENSCINP00000023724	Uncharacterized protein.	Ras-related protein Rab-11B-like.	0.418
F6W350_CIOIN	LOC100178018	ENSCINP00000023791	ENSCINP00000011127	Uncharacterized protein.	Uncharacterized protein.	0.418
F6W350_CIOIN	LOC100178081	ENSCINP00000023791	ENSCINP00000006041	Uncharacterized protein.	Ras-related protein Rab-6A.	0.480
F6W350_CIOIN	LOC100178332	ENSCINP00000023791	ENSCINP00000012228	Uncharacterized protein.	Ras-related protein Rab-9B-like.	0.447
F6W350_CIOIN	LOC100183149	ENSCINP00000023791	ENSCINP00000010211	Uncharacterized protein.	Uncharacterized protein.	0.450
F6W350_CIOIN	LOC100184914	ENSCINP00000023791	ENSCINP00000005841	Uncharacterized protein.	Uncharacterized protein.	0.418
F6XMN3_CIOIN	LOC100176126	ENSCINP00000005725	ENSCINP00000014268	Uncharacterized protein.	Ras-related protein Rab-14.	0.402