(28 nodes) PMP-22/EMP/MP20/Claudin superfamily network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100179981	Uncharacterized protein. (229 aa)
	LOC100179400	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (214 aa)
	H2Y1R0_CIOIN	Uncharacterized protein. (162 aa)
	H2Y1P4_CIOIN	Uncharacterized protein. (174 aa)
	H2XZM8_CIOIN	Uncharacterized protein. (150 aa)
	LOC100177737	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (161 aa)
	LOC100183788	Uncharacterized protein. (167 aa)
	LOC100176521	Peripheral myelin protein 22-like. (181 aa)
	H2XNH4_CIOIN	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (215 aa)
	LOC100180805	Uncharacterized protein LOC100180805. (157 aa)
	LOC100183075	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (215 aa)
	LOC100180326	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
	LOC100186735	Claudin-17-like. (212 aa)
	F6SAZ7_CIOIN	Uncharacterized protein. (187 aa)
	F6PQC6_CIOIN	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (217 aa)
	F6PVF7_CIOIN	Uncharacterized protein. (125 aa)
	F6PSB3_CIOIN	Uncharacterized protein. (225 aa)
	LOC100184472	Claudin-18-like. (176 aa)
	LOC100181662	Uncharacterized protein LOC100181662. (173 aa)
	LOC100180441	Uncharacterized protein LOC100180441. (161 aa)
	LOC100177389	Epithelial membrane protein 2. (165 aa)
	F6WVA9_CIOIN	Uncharacterized protein. (215 aa)
	F6R4U4_CIOIN	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (187 aa)
	F7BCU9_CIOIN	Uncharacterized protein. (165 aa)
	LOC100176657	Claudin-1. (232 aa)
	LOC100186332	Claudin-16-like isoform X1. (274 aa)
	LOC100175766	Uncharacterized protein LOC100175766. (323 aa)
	LOC100183528	Lens fiber membrane intrinsic protein-like. (167 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6PQC6_CIOIN	F6PVF7_CIOIN	ENSCINP00000025375	ENSCINP00000025340	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Uncharacterized protein.	0.537
F6PQC6_CIOIN	F6SAZ7_CIOIN	ENSCINP00000025375	ENSCINP00000026348	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Uncharacterized protein.	0.410
F6PQC6_CIOIN	LOC100180326	ENSCINP00000025375	ENSCINP00000029858	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.551
F6PQC6_CIOIN	LOC100186332	ENSCINP00000025375	ENSCINP00000009847	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin-16-like isoform X1.	0.524
F6PSB3_CIOIN	LOC100180326	ENSCINP00000025043	ENSCINP00000029858	Uncharacterized protein.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.553
F6PSB3_CIOIN	LOC100186332	ENSCINP00000025043	ENSCINP00000009847	Uncharacterized protein.	Claudin-16-like isoform X1.	0.520
F6PVF7_CIOIN	F6PQC6_CIOIN	ENSCINP00000025340	ENSCINP00000025375	Uncharacterized protein.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.537
F6PVF7_CIOIN	F6R4U4_CIOIN	ENSCINP00000025340	ENSCINP00000016825	Uncharacterized protein.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.537
F6PVF7_CIOIN	F6SAZ7_CIOIN	ENSCINP00000025340	ENSCINP00000026348	Uncharacterized protein.	Uncharacterized protein.	0.417
F6PVF7_CIOIN	F6WVA9_CIOIN	ENSCINP00000025340	ENSCINP00000019620	Uncharacterized protein.	Uncharacterized protein.	0.537
F6PVF7_CIOIN	H2XNH4_CIOIN	ENSCINP00000025340	ENSCINP00000031207	Uncharacterized protein.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.537
F6PVF7_CIOIN	LOC100179400	ENSCINP00000025340	ENSCINP00000035894	Uncharacterized protein.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.537
F6PVF7_CIOIN	LOC100179981	ENSCINP00000025340	ENSCINP00000000852	Uncharacterized protein.	Uncharacterized protein.	0.537
F6PVF7_CIOIN	LOC100180326	ENSCINP00000025340	ENSCINP00000029858	Uncharacterized protein.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.537
F6PVF7_CIOIN	LOC100186332	ENSCINP00000025340	ENSCINP00000009847	Uncharacterized protein.	Claudin-16-like isoform X1.	0.522
F6R4U4_CIOIN	F6PVF7_CIOIN	ENSCINP00000016825	ENSCINP00000025340	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Uncharacterized protein.	0.537
F6R4U4_CIOIN	LOC100180326	ENSCINP00000016825	ENSCINP00000029858	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.547
F6R4U4_CIOIN	LOC100186332	ENSCINP00000016825	ENSCINP00000009847	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin-16-like isoform X1.	0.510
F6SAZ7_CIOIN	F6PQC6_CIOIN	ENSCINP00000026348	ENSCINP00000025375	Uncharacterized protein.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.410
F6SAZ7_CIOIN	F6PVF7_CIOIN	ENSCINP00000026348	ENSCINP00000025340	Uncharacterized protein.	Uncharacterized protein.	0.417