(96 nodes) Small GTP-binding protein domain network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100175015	NF-kappa-B inhibitor-interacting Ras-like protein 2 isoform X1. (192 aa)
	LOC100183224	ADP-ribosylation factor-like protein 1; Belongs to the small GTPase superfamily. Arf family. (180 aa)
	LOC100185850	Ras-related protein ORAB-1. (204 aa)
	LOC100182652	dnaJ homolog subfamily C member 27-like isoform X1. (206 aa)
	F6Z156_CIOIN	Uncharacterized protein. (190 aa)
	F6ZET9_CIOIN	Uncharacterized protein. (205 aa)
	LOC100175361	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (197 aa)
	LOC100182890	Uncharacterized protein. (200 aa)
	F6VH27_CIOIN	Uncharacterized protein. (182 aa)
	LOC100176430	ADP-ribosylation factor-like protein 3; Belongs to the small GTPase superfamily. Arf family. (182 aa)
	F6S959_CIOIN	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (163 aa)
	F6UZ38_CIOIN	Uncharacterized protein. (203 aa)
	LOC113474833	Uncharacterized protein. (202 aa)
	rcl1	Rac and Cdc42-like 1 protein. (194 aa)
	F6XND0_CIOIN	Uncharacterized protein. (233 aa)
	LOC100176786	ADP-ribosylation factor 6-like; Belongs to the small GTPase superfamily. Arf family. (202 aa)
	Rac2	Uncharacterized protein. (192 aa)
	LOC100175425	Ras-related protein Rab-11B-like. (217 aa)
	H2Y3T6_CIOIN	Uncharacterized protein. (196 aa)
	Rap1b	Uncharacterized protein. (184 aa)
	LOC100183149	Uncharacterized protein. (214 aa)
	LOC100182217	ADP-ribosylation factor 4-like; Belongs to the small GTPase superfamily. Arf family. (180 aa)
	F6U3B3_CIOIN	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (91 aa)
	LOC104266814	ADP-ribosylation factor 6-like; Belongs to the small GTPase superfamily. Arf family. (174 aa)
	F6RLS6_CIOIN	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (185 aa)
	LOC100183241	Ras-related protein Rab-10-like isoform X1. (207 aa)
	H2Y3F2_CIOIN	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (183 aa)
	LOC100183914	ADP-ribosylation factor 3; Belongs to the small GTPase superfamily. Arf family. (190 aa)
	H2Y1U8_CIOIN	Uncharacterized protein. (232 aa)
	LOC100185836	ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (196 aa)
	Rab2	Uncharacterized protein. (198 aa)
	Rhou	Uncharacterized protein. (259 aa)
	LOC100186168	Ras-related protein Rab-26-like. (223 aa)
	LOC100184752	ADP-ribosylation factor 1; Belongs to the small GTPase superfamily. Arf family. (182 aa)
	LOC100175824	116 kDa U5 small nuclear ribonucleoprotein component. (973 aa)
	F6XKY1_CIOIN	Tr-type G domain-containing protein. (836 aa)
	LOC445704	TC10 protein. (193 aa)
	F6WYJ4_CIOIN	Tr-type G domain-containing protein. (117 aa)
	LOC100183094	Ras-related protein rab7-like. (206 aa)
	LOC100179868	Uncharacterized protein. (199 aa)
	LOC100176126	Ras-related protein Rab-14. (214 aa)
	LOC100185576	Ras-related protein Rab-18. (200 aa)
	COS41.2	Putative Ras-related protein Rab-33. (212 aa)
	LOC100177325	Ras-related protein Rab-4B. (217 aa)
	LOC100181151	Ras-related protein M-Ras. (199 aa)
	LOC100182780	Ras-related protein Rab-3. (220 aa)
	H2XWC7_CIOIN	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (170 aa)
	H2XWC0_CIOIN	Uncharacterized protein. (120 aa)
	LOC100176528	ADP-ribosylation factor-like protein 8B-A; Belongs to the small GTPase superfamily. Arf family. (186 aa)
	LOC100185283	Ras-related protein O-RAL isoform X2. (206 aa)
	F6WS50_CIOIN	OBG-type G domain-containing protein. (358 aa)
	rhob	Rif protein. (249 aa)
	LOC100180756	Ras-related protein RABF2b-like. (215 aa)
	H2XVL7_CIOIN	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (223 aa)
	LOC100187527	ADP-ribosylation factor-like protein 16. (182 aa)
	LOC100184797	Elongation factor G, mitochondrial; Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. (768 aa)
	F6TX56_CIOIN	Tr-type G domain-containing protein. (428 aa)
	LOC100178266	Uncharacterized protein. (213 aa)
	LOC100177266	Uncharacterized protein. (211 aa)
	LOC100178332	Ras-related protein Rab-9B-like. (206 aa)
	LOC100176818	GTP-binding protein SAR1b; Belongs to the small GTPase superfamily. SAR1 family. (192 aa)
	rcl2	Rac and Cdc42-like 2 protein isoform X1. (192 aa)
	LOC100184292	ADP-ribosylation factor-related protein 1-like. (201 aa)
	LOC100178355	ADP-ribosylation factor-like protein 2; Belongs to the small GTPase superfamily. Arf family. (184 aa)
	LOC104266462	ADP-ribosylation factor-like; Belongs to the small GTPase superfamily. Arf family. (200 aa)
	F7A669_CIOIN	Uncharacterized protein. (157 aa)
	LOC448958	Rac5 protein. (193 aa)
	Rac3a	Uncharacterized protein. (194 aa)
	LOC448957	Rac4 protein. (193 aa)
	LOC100179217	GTP-binding protein Rheb. (183 aa)
	F6XTJ3_CIOIN	Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (639 aa)
	LOC100185814	Ras-related protein Rap-2a. (180 aa)
	LOC100182595	Ras-related protein Rab-23. (243 aa)
	rbj	Ras-associated protein Rap1 isoform X1. (267 aa)
	F6PGW6_CIOIN	Tr-type G domain-containing protein. (457 aa)
	LOC100176223	Tr-type G domain-containing protein. (549 aa)
	LOC100178018	Uncharacterized protein. (225 aa)
	LOC445702	Rac1 protein isoform X1. (192 aa)
	LOC100179994	Developmentally-regulated GTP-binding protein 2-like. (364 aa)
	LOC100177212	Uncharacterized protein. (227 aa)
	F6XMN3_CIOIN	Uncharacterized protein. (223 aa)
	LOC100184914	Uncharacterized protein. (206 aa)
	LOC100178081	Ras-related protein Rab-6A. (209 aa)
	rhoc	RhoA protein. (193 aa)
	F6QIK7_CIOIN	Translation factor GUF1 homolog, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner. (625 aa)
	H2XNN6_CIOIN	Uncharacterized protein. (267 aa)
	F6QE09_CIOIN	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (184 aa)
	LOC100177117	Developmentally-regulated GTP-binding protein 1. (367 aa)
	LOC100182193	Ras-related protein Rab-5B. (217 aa)
	F7A713_CIOIN	Tr-type G domain-containing protein. (736 aa)
	F7ABK2_CIOIN	Uncharacterized protein. (585 aa)
	LOC100185418	ADP-ribosylation factor 6-like; Belongs to the small GTPase superfamily. Arf family. (189 aa)
	F6ZKW1_CIOIN	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (161 aa)
	LOC100185758	Ras-related protein Rab-10-like. (202 aa)
	F6VY76_CIOIN	Uncharacterized protein. (210 aa)
	H2XMI8_CIOIN	Uncharacterized protein. (210 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
COS41.2	H2XNN6_CIOIN	ENSCINP00000035150	ENSCINP00000031269	Putative Ras-related protein Rab-33.	Uncharacterized protein.	0.526
COS41.2	LOC100175425	ENSCINP00000035150	ENSCINP00000023724	Putative Ras-related protein Rab-33.	Ras-related protein Rab-11B-like.	0.460
COS41.2	LOC100176818	ENSCINP00000035150	ENSCINP00000011986	Putative Ras-related protein Rab-33.	GTP-binding protein SAR1b; Belongs to the small GTPase superfamily. SAR1 family.	0.454
COS41.2	LOC100178018	ENSCINP00000035150	ENSCINP00000011127	Putative Ras-related protein Rab-33.	Uncharacterized protein.	0.468
COS41.2	LOC100178081	ENSCINP00000035150	ENSCINP00000006041	Putative Ras-related protein Rab-33.	Ras-related protein Rab-6A.	0.509
COS41.2	LOC100178332	ENSCINP00000035150	ENSCINP00000012228	Putative Ras-related protein Rab-33.	Ras-related protein Rab-9B-like.	0.495
COS41.2	LOC100180756	ENSCINP00000035150	ENSCINP00000033812	Putative Ras-related protein Rab-33.	Ras-related protein RABF2b-like.	0.410
COS41.2	LOC100183149	ENSCINP00000035150	ENSCINP00000010211	Putative Ras-related protein Rab-33.	Uncharacterized protein.	0.473
COS41.2	LOC100184914	ENSCINP00000035150	ENSCINP00000005841	Putative Ras-related protein Rab-33.	Uncharacterized protein.	0.484
F6PGW6_CIOIN	F6TX56_CIOIN	ENSCINP00000001445	ENSCINP00000022307	Tr-type G domain-containing protein.	Tr-type G domain-containing protein.	0.627
F6PGW6_CIOIN	F6XTJ3_CIOIN	ENSCINP00000001445	ENSCINP00000003955	Tr-type G domain-containing protein.	Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.	0.440
F6PGW6_CIOIN	LOC100176223	ENSCINP00000001445	ENSCINP00000000257	Tr-type G domain-containing protein.	Tr-type G domain-containing protein.	0.673
F6QE09_CIOIN	LOC100185850	ENSCINP00000006473	ENSCINP00000030419	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.	Ras-related protein ORAB-1.	0.444
F6QIK7_CIOIN	F7A713_CIOIN	ENSCINP00000006440	ENSCINP00000006920	Translation factor GUF1 homolog, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.	Tr-type G domain-containing protein.	0.593
F6QIK7_CIOIN	LOC100176223	ENSCINP00000006440	ENSCINP00000000257	Translation factor GUF1 homolog, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.	Tr-type G domain-containing protein.	0.627
F6RLS6_CIOIN	LOC100185850	ENSCINP00000009643	ENSCINP00000030419	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.	Ras-related protein ORAB-1.	0.444
F6S959_CIOIN	LOC100185850	ENSCINP00000026636	ENSCINP00000030419	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.	Ras-related protein ORAB-1.	0.444
F6TX56_CIOIN	F6PGW6_CIOIN	ENSCINP00000022307	ENSCINP00000001445	Tr-type G domain-containing protein.	Tr-type G domain-containing protein.	0.627
F6TX56_CIOIN	F6WYJ4_CIOIN	ENSCINP00000022307	ENSCINP00000017752	Tr-type G domain-containing protein.	Tr-type G domain-containing protein.	0.705
F6TX56_CIOIN	F6XKY1_CIOIN	ENSCINP00000022307	ENSCINP00000019008	Tr-type G domain-containing protein.	Tr-type G domain-containing protein.	0.713