(9 nodes) Actin/actin-like conserved site network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100184134	Actin, muscle-type. (378 aa)
	F6QBJ1_CIOIN	Uncharacterized protein. (378 aa)
	F6SCP4_CIOIN	Uncharacterized protein. (377 aa)
	H2XW16_CIOIN	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (216 aa)
	act	Act protein isoform X1. (375 aa)
	F6Q662_CIOIN	Uncharacterized protein. (370 aa)
	LOC100176797	Actin, muscle-like. (378 aa)
	LOC100183636	Actin, muscle. (378 aa)
	F6TVZ8_CIOIN	Uncharacterized protein; Belongs to the actin family. (378 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6Q662_CIOIN	F6TVZ8_CIOIN	ENSCINP00000018172	ENSCINP00000015449	Uncharacterized protein.	Uncharacterized protein; Belongs to the actin family.	0.440
F6Q662_CIOIN	H2XW16_CIOIN	ENSCINP00000018172	ENSCINP00000033850	Uncharacterized protein.	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	0.633
F6Q662_CIOIN	LOC100176797	ENSCINP00000018172	ENSCINP00000014691	Uncharacterized protein.	Actin, muscle-like.	0.543
F6Q662_CIOIN	LOC100183636	ENSCINP00000018172	ENSCINP00000002686	Uncharacterized protein.	Actin, muscle.	0.543
F6Q662_CIOIN	LOC100184134	ENSCINP00000018172	ENSCINP00000015480	Uncharacterized protein.	Actin, muscle-type.	0.543
F6QBJ1_CIOIN	F6TVZ8_CIOIN	ENSCINP00000018112	ENSCINP00000015449	Uncharacterized protein.	Uncharacterized protein; Belongs to the actin family.	0.438
F6QBJ1_CIOIN	H2XW16_CIOIN	ENSCINP00000018112	ENSCINP00000033850	Uncharacterized protein.	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	0.631
F6SCP4_CIOIN	F6TVZ8_CIOIN	ENSCINP00000017903	ENSCINP00000015449	Uncharacterized protein.	Uncharacterized protein; Belongs to the actin family.	0.438
F6SCP4_CIOIN	H2XW16_CIOIN	ENSCINP00000017903	ENSCINP00000033850	Uncharacterized protein.	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	0.631
F6TVZ8_CIOIN	F6Q662_CIOIN	ENSCINP00000015449	ENSCINP00000018172	Uncharacterized protein; Belongs to the actin family.	Uncharacterized protein.	0.440
F6TVZ8_CIOIN	F6QBJ1_CIOIN	ENSCINP00000015449	ENSCINP00000018112	Uncharacterized protein; Belongs to the actin family.	Uncharacterized protein.	0.438
F6TVZ8_CIOIN	F6SCP4_CIOIN	ENSCINP00000015449	ENSCINP00000017903	Uncharacterized protein; Belongs to the actin family.	Uncharacterized protein.	0.438
F6TVZ8_CIOIN	H2XW16_CIOIN	ENSCINP00000015449	ENSCINP00000033850	Uncharacterized protein; Belongs to the actin family.	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	0.654
F6TVZ8_CIOIN	LOC100176797	ENSCINP00000015449	ENSCINP00000014691	Uncharacterized protein; Belongs to the actin family.	Actin, muscle-like.	0.439
F6TVZ8_CIOIN	LOC100183636	ENSCINP00000015449	ENSCINP00000002686	Uncharacterized protein; Belongs to the actin family.	Actin, muscle.	0.438
F6TVZ8_CIOIN	LOC100184134	ENSCINP00000015449	ENSCINP00000015480	Uncharacterized protein; Belongs to the actin family.	Actin, muscle-type.	0.438
F6TVZ8_CIOIN	act	ENSCINP00000015449	ENSCINP00000001538	Uncharacterized protein; Belongs to the actin family.	Act protein isoform X1.	0.438
H2XW16_CIOIN	F6Q662_CIOIN	ENSCINP00000033850	ENSCINP00000018172	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	Uncharacterized protein.	0.633
H2XW16_CIOIN	F6QBJ1_CIOIN	ENSCINP00000033850	ENSCINP00000018112	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	Uncharacterized protein.	0.631
H2XW16_CIOIN	F6SCP4_CIOIN	ENSCINP00000033850	ENSCINP00000017903	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	Uncharacterized protein.	0.631