(95 nodes) Thioredoxin-like superfamily network (Ciona intestinalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	H2XYK0_CIOIN	L51_S25_CI-B8 domain-containing protein. (140 aa)
	LOC100187268	Thioredoxin domain-containing protein. (302 aa)
	Txnrd3	Glutaredoxin domain-containing protein. (596 aa)
	H2Y1S7_CIOIN	Thioredoxin domain-containing protein; Belongs to the protein disulfide isomerase family. (177 aa)
	gpx_d	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (165 aa)
	H2XZE7_CIOIN	Glutaredoxin domain-containing protein. (133 aa)
	LOC100181030	Thioredoxin; Belongs to the thioredoxin family. (106 aa)
	H2XXK5_CIOIN	Thioredoxin domain-containing protein. (429 aa)
	H2XWK0_CIOIN	Uncharacterized protein. (90 aa)
	LOC101243377	Migration and invasion enhancer 1. (76 aa)
	LOC100175802	Peroxiredoxin-like. (235 aa)
	H2XTK8_CIOIN	Thioredoxin domain-containing protein. (221 aa)
	H2XTI3_CIOIN	Thioredoxin domain-containing protein. (143 aa)
	LOC100181245	Glutaredoxin-like. (107 aa)
	LOC100175262	Thioredoxin domain-containing protein 17-like. (124 aa)
	LOC100184789	SH3 domain-binding glutamic acid-rich-like protein 2. (116 aa)
	H2XQS5_CIOIN	Thioredoxin domain-containing protein. (223 aa)
	H2XQD9_CIOIN	Uncharacterized protein; Belongs to the GST superfamily. (222 aa)
	H2XPC7_CIOIN	Uncharacterized protein. (175 aa)
	H2XP81_CIOIN	Thioredoxin domain-containing protein. (144 aa)
	LOC100186348	Glutathione S-transferase kappa. (225 aa)
	dsba	DSBA domain-containing protein. (186 aa)
	H2XLA5_CIOIN	Uncharacterized protein; Belongs to the GST superfamily. (224 aa)
	H2XK87_CIOIN	Uncharacterized protein. (231 aa)
	LOC100175288	Thioredoxin domain-containing protein. (168 aa)
	F7AK54_CIOIN	Glutaredoxin domain-containing protein. (100 aa)
	F6QU62_CIOIN	J domain-containing protein. (430 aa)
	F6Z6P7_CIOIN	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (264 aa)
	LOC100186966	Uncharacterized protein. (202 aa)
	F7BGP0_CIOIN	Thioredoxin domain-containing protein. (191 aa)
	F6TYK2_CIOIN	L51_S25_CI-B8 domain-containing protein. (49 aa)
	F6PWH2_CIOIN	Uncharacterized protein. (201 aa)
	LOC100180334	Uncharacterized protein LOC100180334 isoform X1. (409 aa)
	LOC100177239	Hematopoietic prostaglandin D synthase; Belongs to the GST superfamily. (197 aa)
	F7AI05_CIOIN	Glutaredoxin; Belongs to the glutaredoxin family. Monothiol subfamily. (153 aa)
	LOC100183957	Thioredoxin; Belongs to the thioredoxin family. (107 aa)
	F7BMH5_CIOIN	UBX domain-containing protein. (447 aa)
	LOC100179175	Uncharacterized protein. (817 aa)
	gpx7	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (190 aa)
	LOC100185726	Thioredoxin domain-containing protein. (466 aa)
	F6XUL4_CIOIN	Uncharacterized protein; Belongs to the GST superfamily. (223 aa)
	LOC100178653	Glutathione S-transferase Mu 1-like. (225 aa)
	LOC100180700	Thioredoxin domain-containing protein 9-like. (219 aa)
	F7AY96_CIOIN	Uncharacterized protein; Belongs to the GST superfamily. (241 aa)
	F6QDM9_CIOIN	Uncharacterized protein; Belongs to the GST superfamily. (221 aa)
	F6RAJ1_CIOIN	Uncharacterized protein; Belongs to the GST superfamily. (254 aa)
	LOC100177610	Peroxiredoxin-6-like isoform X1. (222 aa)
	LOC100184221	Protein SCO1 homolog, mitochondrial-like. (291 aa)
	LOC100177836	Thioredoxin domain-containing protein 16-like. (457 aa)
	LOC100179669	Glutathione S-transferase omega-1-like; Belongs to the GST superfamily. (245 aa)
	F7AHC2_CIOIN	Uncharacterized protein. (219 aa)
	F7AHD2_CIOIN	Uncharacterized protein; Belongs to the GST superfamily. (221 aa)
	LOC100178265	Glutathione S-transferase 1; Belongs to the GST superfamily. (224 aa)
	LOC100181381	UBX domain-containing protein. (367 aa)
	F7AEM1_CIOIN	Uncharacterized protein. (520 aa)
	F6ZCR7_CIOIN	Uncharacterized protein. (172 aa)
	LOC100176262	Thioredoxin-like protein AAED1. (213 aa)
	ciic3	Thioredoxin domain-containing protein 3 homolog; May be required during the final stages of sperm tail maturation. May act by reducing disulfide bonds within the sperm components (By similarity). (653 aa)
	LOC100180659	Probable thioredoxin-2. (175 aa)
	F6QQZ3_CIOIN	Thioredoxin domain-containing protein. (202 aa)
	LOC100184179	Protein disulfide-isomerase. (630 aa)
	LOC100179946	Phosducin-like protein. (257 aa)
	F6VQ32_CIOIN	Uncharacterized protein; Belongs to the GST superfamily. (198 aa)
	LOC100176187	Uncharacterized protein; Belongs to the GST superfamily. (244 aa)
	L7N0S5_CIOIN	Uncharacterized protein; Belongs to the GST superfamily. (180 aa)
	F7AV59_CIOIN	Uncharacterized protein; Belongs to the GST superfamily. (250 aa)
	F6V9K6_CIOIN	Uncharacterized protein. (224 aa)
	F6REV8_CIOIN	L51_S25_CI-B8 domain-containing protein. (184 aa)
	LOC100179685	Uncharacterized protein. (276 aa)
	F6Y3D6_CIOIN	Uncharacterized protein; Belongs to the GST superfamily. (222 aa)
	F7BDX5_CIOIN	Uncharacterized protein; Belongs to the GST superfamily. (204 aa)
	F7BPM3_CIOIN	UBX domain-containing protein. (342 aa)
	F6TUR1_CIOIN	Thioredoxin domain-containing protein; Belongs to the protein disulfide isomerase family. (373 aa)
	F6TXN5_CIOIN	Uncharacterized protein. (245 aa)
	LOC100179436	Thioredoxin domain-containing protein isoform X2. (316 aa)
	F7BHL8_CIOIN	Uncharacterized protein. (404 aa)
	LOC104266621	Uncharacterized protein LOC104266621. (357 aa)
	LOC100182315	Protein disulfide-isomerase. (503 aa)
	per-like	Peroxiredoxin-like. (197 aa)
	F6WYW5_CIOIN	Protein disulfide-isomerase. (488 aa)
	F7B496_CIOIN	Phosducin domain-containing protein. (235 aa)
	F6PPC0_CIOIN	Uncharacterized protein. (414 aa)
	F6WRW7_CIOIN	Uncharacterized protein; Belongs to the GST superfamily. (231 aa)
	LOC100184961	Glutathione S-transferase 1-1-like isoform X1; Belongs to the GST superfamily. (226 aa)
	F6WST8_CIOIN	Glutaredoxin domain-containing protein. (487 aa)
	LOC100186125	Glutaredoxin-3. (330 aa)
	LOC100184901	Uncharacterized protein. (330 aa)
	F6X863_CIOIN	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (217 aa)
	LOC100179151	Glutathione S-transferase theta-1-like. (216 aa)
	F6YRS8_CIOIN	Thioredoxin domain-containing protein. (406 aa)
	F7AE92_CIOIN	Uncharacterized protein; Belongs to the GST superfamily. (211 aa)
	Gpx_c	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (139 aa)
	LOC100175706	Glutaredoxin domain-containing protein. (285 aa)
	LOC100182061	Uncharacterized protein; Belongs to the GST superfamily. (202 aa)
	LOC100184425	Glutathione S-transferase 1-like. (199 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6PPC0_CIOIN	F7AV59_CIOIN	ENSCINP00000004711	ENSCINP00000011374	Uncharacterized protein.	Uncharacterized protein; Belongs to the GST superfamily.	0.400
F6PPC0_CIOIN	F7AY96_CIOIN	ENSCINP00000004711	ENSCINP00000021581	Uncharacterized protein.	Uncharacterized protein; Belongs to the GST superfamily.	0.400
F6PPC0_CIOIN	L7N0S5_CIOIN	ENSCINP00000004711	ENSCINP00000011377	Uncharacterized protein.	Uncharacterized protein; Belongs to the GST superfamily.	0.400
F6PPC0_CIOIN	LOC100176187	ENSCINP00000004711	ENSCINP00000011385	Uncharacterized protein.	Uncharacterized protein; Belongs to the GST superfamily.	0.400
F6PPC0_CIOIN	LOC100179175	ENSCINP00000004711	ENSCINP00000024096	Uncharacterized protein.	Uncharacterized protein.	0.644
F6PPC0_CIOIN	LOC100179669	ENSCINP00000004711	ENSCINP00000017658	Uncharacterized protein.	Glutathione S-transferase omega-1-like; Belongs to the GST superfamily.	0.400
F6PPC0_CIOIN	LOC100181030	ENSCINP00000004711	ENSCINP00000034464	Uncharacterized protein.	Thioredoxin; Belongs to the thioredoxin family.	0.534
F6PPC0_CIOIN	LOC100183957	ENSCINP00000004711	ENSCINP00000024533	Uncharacterized protein.	Thioredoxin; Belongs to the thioredoxin family.	0.534
F6PPC0_CIOIN	LOC104266621	ENSCINP00000004711	ENSCINP00000006796	Uncharacterized protein.	Uncharacterized protein LOC104266621.	0.611
F6PPC0_CIOIN	ciic3	ENSCINP00000004711	ENSCINP00000013583	Uncharacterized protein.	Thioredoxin domain-containing protein 3 homolog; May be required during the final stages of sperm tail maturation. May act by reducing disulfide bonds within the sperm components (By similarity).	0.770
F6PWH2_CIOIN	F6VQ32_CIOIN	ENSCINP00000025320	ENSCINP00000012909	Uncharacterized protein.	Uncharacterized protein; Belongs to the GST superfamily.	0.902
F6PWH2_CIOIN	F7BDX5_CIOIN	ENSCINP00000025320	ENSCINP00000009038	Uncharacterized protein.	Uncharacterized protein; Belongs to the GST superfamily.	0.902
F6PWH2_CIOIN	LOC100175706	ENSCINP00000025320	ENSCINP00000001257	Uncharacterized protein.	Glutaredoxin domain-containing protein.	0.900
F6PWH2_CIOIN	LOC100177239	ENSCINP00000025320	ENSCINP00000025179	Uncharacterized protein.	Hematopoietic prostaglandin D synthase; Belongs to the GST superfamily.	0.902
F6PWH2_CIOIN	LOC100182061	ENSCINP00000025320	ENSCINP00000001243	Uncharacterized protein.	Uncharacterized protein; Belongs to the GST superfamily.	0.902
F6PWH2_CIOIN	LOC100184425	ENSCINP00000025320	ENSCINP00000000153	Uncharacterized protein.	Glutathione S-transferase 1-like.	0.902
F6PWH2_CIOIN	LOC100186966	ENSCINP00000025320	ENSCINP00000027377	Uncharacterized protein.	Uncharacterized protein.	0.902
F6QQZ3_CIOIN	F6TUR1_CIOIN	ENSCINP00000013246	ENSCINP00000008588	Thioredoxin domain-containing protein.	Thioredoxin domain-containing protein; Belongs to the protein disulfide isomerase family.	0.637
F6QQZ3_CIOIN	F6YRS8_CIOIN	ENSCINP00000013246	ENSCINP00000002784	Thioredoxin domain-containing protein.	Thioredoxin domain-containing protein.	0.844
F6QQZ3_CIOIN	F7BHL8_CIOIN	ENSCINP00000013246	ENSCINP00000007213	Thioredoxin domain-containing protein.	Uncharacterized protein.	0.730