(29 nodes) Gamma carboxylation, hypusine formation and arylsulfatase activation network (Ciona intestinalis)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Predicted Interactions

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Your Input:
	LOC100181968	TP_methylase domain-containing protein. (285 aa)
	F6XKZ0_CIOIN	EFG_C domain-containing protein. (162 aa)
	F6XKY1_CIOIN	Tr-type G domain-containing protein. (836 aa)
	F6XKX5_CIOIN	GTP_EFTU_D2 domain-containing protein. (333 aa)
	F6UAS2_CIOIN	Sulfatase domain-containing protein. (527 aa)
	F6RX41_CIOIN	Uncharacterized protein. (148 aa)
	F7BEW6_CIOIN	Sulfatase domain-containing protein. (260 aa)
	LOC100187300	Leucine-rich repeat and IQ domain-containing protein 4-like isoform X3. (605 aa)
	F6PT55_CIOIN	FGE-sulfatase domain-containing protein. (377 aa)
	F6UE78_CIOIN	Diphthami_syn_2 domain-containing protein. (536 aa)
	F6TD07_CIOIN	Uncharacterized protein. (369 aa)
	Ggcx	Uncharacterized protein. (354 aa)
	H2XRT9_CIOIN	Sulfatase domain-containing protein. (574 aa)
	H2XSF5_CIOIN	Sulfatase domain-containing protein. (491 aa)
	H2XSS0_CIOIN	eIF-5a domain-containing protein. (99 aa)
	LOC100181314	2-(3-amino-3-carboxypropyl)histidine synthase subunit 2. (510 aa)
	F6YUN5_CIOIN	WD_REPEATS_REGION domain-containing protein. (355 aa)
	F6TN28_CIOIN	Uncharacterized protein; Belongs to the fructosamine kinase family. (308 aa)
	LOC100187202	Sulfatase domain-containing protein. (515 aa)
	F6TJ09_CIOIN	Sulfatase domain-containing protein. (238 aa)
	F6ZL08_CIOIN	HTTM domain-containing protein. (234 aa)
	F6YWW9_CIOIN	P/Homo B domain-containing protein; Belongs to the peptidase S8 family. (688 aa)
	LOC113474034	P/Homo B domain-containing protein; Belongs to the peptidase S8 family. (607 aa)
	F6TZG1_CIOIN	Sulfatase domain-containing protein. (492 aa)
	F6VZF6_CIOIN	2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2. (397 aa)
	F7AJZ2_CIOIN	Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor; Belongs to the deoxyhypusine hydroxylase family. (313 aa)
	F6WYJ4_CIOIN	Tr-type G domain-containing protein. (117 aa)
	LOC100181424	Uncharacterized protein. (719 aa)
	F6QYI8_CIOIN	Sulfatase domain-containing protein. (244 aa)

Your Current Organism:

Ciona intestinalis

NCBI taxonomy Id: 7719
Other names: Ascidia intestinalis, C. intestinalis, sea vase, vase tunicate, yellow sea squirt

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F6PT55_CIOIN	F6QYI8_CIOIN	ENSCINP00000023886	ENSCINP00000018053	FGE-sulfatase domain-containing protein.	Sulfatase domain-containing protein.	0.560
F6PT55_CIOIN	F6TZG1_CIOIN	ENSCINP00000023886	ENSCINP00000013992	FGE-sulfatase domain-containing protein.	Sulfatase domain-containing protein.	0.554
F6PT55_CIOIN	F6UAS2_CIOIN	ENSCINP00000023886	ENSCINP00000021407	FGE-sulfatase domain-containing protein.	Sulfatase domain-containing protein.	0.677
F6PT55_CIOIN	F7BEW6_CIOIN	ENSCINP00000023886	ENSCINP00000023003	FGE-sulfatase domain-containing protein.	Sulfatase domain-containing protein.	0.560
F6PT55_CIOIN	H2XRT9_CIOIN	ENSCINP00000023886	ENSCINP00000032373	FGE-sulfatase domain-containing protein.	Sulfatase domain-containing protein.	0.726
F6PT55_CIOIN	H2XSF5_CIOIN	ENSCINP00000023886	ENSCINP00000032589	FGE-sulfatase domain-containing protein.	Sulfatase domain-containing protein.	0.549
F6PT55_CIOIN	LOC100181424	ENSCINP00000023886	ENSCINP00000017836	FGE-sulfatase domain-containing protein.	Uncharacterized protein.	0.476
F6PT55_CIOIN	LOC100187202	ENSCINP00000023886	ENSCINP00000007178	FGE-sulfatase domain-containing protein.	Sulfatase domain-containing protein.	0.562
F6QYI8_CIOIN	F6PT55_CIOIN	ENSCINP00000018053	ENSCINP00000023886	Sulfatase domain-containing protein.	FGE-sulfatase domain-containing protein.	0.560
F6QYI8_CIOIN	F6TJ09_CIOIN	ENSCINP00000018053	ENSCINP00000007764	Sulfatase domain-containing protein.	Sulfatase domain-containing protein.	0.941
F6QYI8_CIOIN	F6UAS2_CIOIN	ENSCINP00000018053	ENSCINP00000021407	Sulfatase domain-containing protein.	Sulfatase domain-containing protein.	0.432
F6QYI8_CIOIN	H2XRT9_CIOIN	ENSCINP00000018053	ENSCINP00000032373	Sulfatase domain-containing protein.	Sulfatase domain-containing protein.	0.403
F6TD07_CIOIN	F7AJZ2_CIOIN	ENSCINP00000025651	ENSCINP00000017057	Uncharacterized protein.	Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor; Belongs to the deoxyhypusine hydroxylase family.	0.915
F6TD07_CIOIN	H2XSS0_CIOIN	ENSCINP00000025651	ENSCINP00000032704	Uncharacterized protein.	eIF-5a domain-containing protein.	0.990
F6TJ09_CIOIN	F6QYI8_CIOIN	ENSCINP00000007764	ENSCINP00000018053	Sulfatase domain-containing protein.	Sulfatase domain-containing protein.	0.941
F6TJ09_CIOIN	F6UAS2_CIOIN	ENSCINP00000007764	ENSCINP00000021407	Sulfatase domain-containing protein.	Sulfatase domain-containing protein.	0.565
F6TJ09_CIOIN	F7BEW6_CIOIN	ENSCINP00000007764	ENSCINP00000023003	Sulfatase domain-containing protein.	Sulfatase domain-containing protein.	0.940
F6TJ09_CIOIN	H2XRT9_CIOIN	ENSCINP00000007764	ENSCINP00000032373	Sulfatase domain-containing protein.	Sulfatase domain-containing protein.	0.571
F6TZG1_CIOIN	F6PT55_CIOIN	ENSCINP00000013992	ENSCINP00000023886	Sulfatase domain-containing protein.	FGE-sulfatase domain-containing protein.	0.554
F6TZG1_CIOIN	F6UAS2_CIOIN	ENSCINP00000013992	ENSCINP00000021407	Sulfatase domain-containing protein.	Sulfatase domain-containing protein.	0.449